The gene/protein map for NC_007347 is currently unavailable.
Definition Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession NC_007347
Length 3,806,533

Click here to switch to the map view.

The map label for this gene is hmuV [H]

Identifier: 73540362

GI number: 73540362

Start: 705433

End: 706269

Strand: Direct

Name: hmuV [H]

Synonym: Reut_A0656

Alternate gene names: 73540362

Gene position: 705433-706269 (Clockwise)

Preceding gene: 73540361

Following gene: 73540363

Centisome position: 18.53

GC content: 69.53

Gene sequence:

>837_bases
ATGACGCACTGGTCCGAACCCGCAGCCGCATGCTCCACGCTGTCCCTGCACGACGTGAGCCTGCGCACCGGCACGCGCGT
GCTGGTCGATGGCCTGTCGCTCGAGATCGCACCGGGACAGCTCTGGTGCGTGGCCGGACCCAATGGCGTCGGCAAATCCA
CGCTGATGGGCGTGCTTTCGGGCCTGCGCCGCGCCGATGGTGGCAGCGCCAGCCTGGACGGCACGTCACTGGAGCGACTG
TCGCCGGCCGCACTGGCACGCCAGCGTGCCTACCTGCCACAGGCCCTGCATGACACGTTCTCGATGTCCGTGCTCGACGC
GGTGCGCGTGGGCCGCCATCCGCACCTGTCCGGCTGGGGCTGGACCGGGCGCGATGACGATGCCGTGGTACGCGCCGCCA
TTGATGCCATGGACCTTGAAACGCTGTCCGCACGCGACGTACTGACGCTGTCCGGCGGTGAACGCCAGCGCGCGGCGCTG
GCCGCCGTGCTTGCGCAGCAGGCGCCGCTGCTGCTGCTCGACGAACCCGTCTCGCACCTGGACTTGCGGCACCAGATCAT
GGTGCTCGAAGTGCTCGCGTCGCTGGCGCGTGCGGGCCGCCATGCGATCGTCGTGATCCTGCACGACCTGAACCTGGCGC
GCCGCTACGCCACCCATGCGCTGCTGATGGCCGAAGACGGCACGGCGCTGCATGGCCCGGCACAGCAGGTGCTGACCCCC
GAACAATGCTCGCGCGCGCTGCGCACGCCGATCGTCAGCGTGACTGACGGCGTCCACACCGCGCTGATTCCCGATGGATT
TCCCCGCCCGCGGGCGGGCACGAACGAACAATCATGA

Upstream 100 bases:

>100_bases
TCGCACGTACCGTGATCGCGCCCGCACAGCTGCCAGTGGGCGTCATTACTGCGTTGCTTGGCGTGCCGACCTTCCTCTAC
CTGCTGTTGCGGAGGCCGCG

Downstream 100 bases:

>100_bases
ACGACAACACGACAGCACAGGGCGGCGGCACGGACGATGGCGGCCGCGACGAGCGCCACAAGGCCCGCATGGTCCGCAAG
AAGGAAGTGGTCGACGCGAA

Product: ABC transporter related

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTHWSEPAAACSTLSLHDVSLRTGTRVLVDGLSLEIAPGQLWCVAGPNGVGKSTLMGVLSGLRRADGGSASLDGTSLERL
SPAALARQRAYLPQALHDTFSMSVLDAVRVGRHPHLSGWGWTGRDDDAVVRAAIDAMDLETLSARDVLTLSGGERQRAAL
AAVLAQQAPLLLLDEPVSHLDLRHQIMVLEVLASLARAGRHAIVVILHDLNLARRYATHALLMAEDGTALHGPAQQVLTP
EQCSRALRTPIVSVTDGVHTALIPDGFPRPRAGTNEQS

Sequences:

>Translated_278_residues
MTHWSEPAAACSTLSLHDVSLRTGTRVLVDGLSLEIAPGQLWCVAGPNGVGKSTLMGVLSGLRRADGGSASLDGTSLERL
SPAALARQRAYLPQALHDTFSMSVLDAVRVGRHPHLSGWGWTGRDDDAVVRAAIDAMDLETLSARDVLTLSGGERQRAAL
AAVLAQQAPLLLLDEPVSHLDLRHQIMVLEVLASLARAGRHAIVVILHDLNLARRYATHALLMAEDGTALHGPAQQVLTP
EQCSRALRTPIVSVTDGVHTALIPDGFPRPRAGTNEQS
>Mature_277_residues
THWSEPAAACSTLSLHDVSLRTGTRVLVDGLSLEIAPGQLWCVAGPNGVGKSTLMGVLSGLRRADGGSASLDGTSLERLS
PAALARQRAYLPQALHDTFSMSVLDAVRVGRHPHLSGWGWTGRDDDAVVRAAIDAMDLETLSARDVLTLSGGERQRAALA
AVLAQQAPLLLLDEPVSHLDLRHQIMVLEVLASLARAGRHAIVVILHDLNLARRYATHALLMAEDGTALHGPAQQVLTPE
QCSRALRTPIVSVTDGVHTALIPDGFPRPRAGTNEQS

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI108773784, Length=180, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI108773782, Length=180, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI46592956, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI46592964, Length=188, Percent_Identity=30.3191489361702, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI46592971, Length=188, Percent_Identity=30.3191489361702, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI46592978, Length=188, Percent_Identity=30.3191489361702, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI46592898, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI46592915, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI42741659, Length=241, Percent_Identity=29.8755186721992, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI9665248, Length=256, Percent_Identity=26.953125, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4505771, Length=259, Percent_Identity=28.957528957529, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI215820660, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20143975, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI9961252, Length=259, Percent_Identity=28.957528957529, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI156105685, Length=216, Percent_Identity=30.5555555555556, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9961250, Length=266, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI47078218, Length=208, Percent_Identity=25, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI45446740, Length=208, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI153792144, Length=171, Percent_Identity=28.6549707602339, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9955968, Length=230, Percent_Identity=27.3913043478261, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI9955966, Length=230, Percent_Identity=27.3913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI45243524, Length=230, Percent_Identity=27.3913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9955963, Length=190, Percent_Identity=31.0526315789474, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI21536378, Length=239, Percent_Identity=28.8702928870293, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=228, Percent_Identity=36.8421052631579, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786803, Length=236, Percent_Identity=36.0169491525424, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1786345, Length=208, Percent_Identity=39.9038461538462, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788002, Length=222, Percent_Identity=34.2342342342342, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787712, Length=258, Percent_Identity=29.8449612403101, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=29.1079812206573, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=30.5936073059361, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788761, Length=244, Percent_Identity=27.8688524590164, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790544, Length=218, Percent_Identity=29.8165137614679, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=243, Percent_Identity=29.2181069958848, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788165, Length=204, Percent_Identity=30.3921568627451, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789873, Length=212, Percent_Identity=30.6603773584906, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789864, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789032, Length=234, Percent_Identity=30.3418803418803, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789751, Length=214, Percent_Identity=31.3084112149533, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788506, Length=222, Percent_Identity=29.2792792792793, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789891, Length=200, Percent_Identity=32, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786698, Length=198, Percent_Identity=26.2626262626263, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082267, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787972, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786398, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787143, Length=203, Percent_Identity=28.0788177339901, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788450, Length=226, Percent_Identity=27.8761061946903, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790525, Length=211, Percent_Identity=28.9099526066351, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788472, Length=186, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787500, Length=209, Percent_Identity=28.7081339712919, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786563, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790467, Length=210, Percent_Identity=28.0952380952381, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786872, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790162, Length=223, Percent_Identity=27.8026905829596, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=230, Percent_Identity=26.9565217391304, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788210, Length=187, Percent_Identity=29.9465240641711, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994883, Length=224, Percent_Identity=28.125, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786319, Length=155, Percent_Identity=29.6774193548387, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787112, Length=239, Percent_Identity=27.1966527196653, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786975, Length=208, Percent_Identity=25, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787105, Length=210, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789593, Length=235, Percent_Identity=25.531914893617, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=205, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71992285, Length=241, Percent_Identity=27.3858921161826, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=245, Percent_Identity=29.3877551020408, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558664, Length=226, Percent_Identity=28.7610619469027, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555800, Length=176, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=197, Percent_Identity=25.8883248730964, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539902, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=225, Percent_Identity=30.2222222222222, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324498, Length=256, Percent_Identity=24.21875, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161076682, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI161076684, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24581617, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24581615, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI85816269, Length=264, Percent_Identity=26.1363636363636, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24580553, Length=264, Percent_Identity=26.1363636363636, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85724864, Length=264, Percent_Identity=26.1363636363636, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24580555, Length=264, Percent_Identity=26.1363636363636, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24661270, Length=180, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355589, Length=180, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574744, Length=222, Percent_Identity=27.9279279279279, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24650853, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362751, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650855, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85726357, Length=222, Percent_Identity=28.8288288288288, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29536; Mature: 29405

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTHWSEPAAACSTLSLHDVSLRTGTRVLVDGLSLEIAPGQLWCVAGPNGVGKSTLMGVLS
CCCCCCCHHHHHCCEEEEEECCCCCEEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHH
GLRRADGGSASLDGTSLERLSPAALARQRAYLPQALHDTFSMSVLDAVRVGRHPHLSGWG
HHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WTGRDDDAVVRAAIDAMDLETLSARDVLTLSGGERQRAALAAVLAQQAPLLLLDEPVSHL
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHH
DLRHQIMVLEVLASLARAGRHAIVVILHDLNLARRYATHALLMAEDGTALHGPAQQVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHEEEEECCCCCCCCCHHHCCCH
EQCSRALRTPIVSVTDGVHTALIPDGFPRPRAGTNEQS
HHHHHHHHCCEEEECCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THWSEPAAACSTLSLHDVSLRTGTRVLVDGLSLEIAPGQLWCVAGPNGVGKSTLMGVLS
CCCCCCHHHHHCCEEEEEECCCCCEEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHH
GLRRADGGSASLDGTSLERLSPAALARQRAYLPQALHDTFSMSVLDAVRVGRHPHLSGWG
HHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WTGRDDDAVVRAAIDAMDLETLSARDVLTLSGGERQRAALAAVLAQQAPLLLLDEPVSHL
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHH
DLRHQIMVLEVLASLARAGRHAIVVILHDLNLARRYATHALLMAEDGTALHGPAQQVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHEEEEECCCCCCCCCHHHCCCH
EQCSRALRTPIVSVTDGVHTALIPDGFPRPRAGTNEQS
HHHHHHHHCCEEEECCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA