Click here to switch to the map view.

The map label for this gene is cobO [H]

Identifier: 73540363

GI number: 73540363

Start: 706266

End: 706907

Strand: Direct

Name: cobO [H]

Synonym: Reut_A0657

Alternate gene names: 73540363

Gene position: 706266-706907 (Clockwise)

Preceding gene: 73540362

Following gene: 73540364

Centisome position: 18.55

GC content: 66.98

Gene sequence:

>642_bases
ATGAACGACAACACGACAGCACAGGGCGGCGGCACGGACGATGGCGGCCGCGACGAGCGCCACAAGGCCCGCATGGTCCG
CAAGAAGGAAGTGGTCGACGCGAAAATCGCCGCCGCGCAGGACGAGCGCGGCGTGATCGTCATCACGACCGGCAATGGCA
AGGGAAAGTCGAGCTCAGGCTTCGGCATGGTGGTGCGTGCGCTCGGCCACGGCATGCGGACCGGCGTGGTGCAGTTCATC
AAGGGCGAGCAGCCCACCGGCGAGGAGATGTTCCTTCGCCGCTTCCCCGATGTCTGCGACTTCCATGTGATGGGCGAAGG
CTACACGTGGGAGACGCAGGACCGCGCGCGTGATGTGGCCAAGGCAGAAGCGGCCTGGGAAGTGGCGCGCGGCATGCTGC
GCGACCCGTCGATCGGGCTCGTGCTGTTCGACGAACTCAACATCGCGCTCAAGCTGCACTATCTTGATGTGGAGCGCGTG
GTCGAGGACCTGCGCGCGCGGCCACCGATGCAGCACGTGGTCATCACCGGCCGTGGCGCGCCGCCGGCGCTGGTGGAAGC
AGCGGACACCGTCACCGACATGGTGCCGGTCAAGCACGCGTTCCAGCAGGGCATCAAGGCGCAGCGCGGCGTGGAGATGT
AG

Upstream 100 bases:

>100_bases
GCGCGCTGCGCACGCCGATCGTCAGCGTGACTGACGGCGTCCACACCGCGCTGATTCCCGATGGATTTCCCCGCCCGCGG
GCGGGCACGAACGAACAATC

Downstream 100 bases:

>100_bases
CGGTACACTGCGCCCGATTCATTTTTATCCGTATTCATTGCGCACCATGCTGTTTCCAGAAATCGCCCCCCTCGACGACG
CGCTGCGTCCGGCCCTGCGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNDNTTAQGGGTDDGGRDERHKARMVRKKEVVDAKIAAAQDERGVIVITTGNGKGKSSSGFGMVVRALGHGMRTGVVQFI
KGEQPTGEEMFLRRFPDVCDFHVMGEGYTWETQDRARDVAKAEAAWEVARGMLRDPSIGLVLFDELNIALKLHYLDVERV
VEDLRARPPMQHVVITGRGAPPALVEAADTVTDMVPVKHAFQQGIKAQRGVEM

Sequences:

>Translated_213_residues
MNDNTTAQGGGTDDGGRDERHKARMVRKKEVVDAKIAAAQDERGVIVITTGNGKGKSSSGFGMVVRALGHGMRTGVVQFI
KGEQPTGEEMFLRRFPDVCDFHVMGEGYTWETQDRARDVAKAEAAWEVARGMLRDPSIGLVLFDELNIALKLHYLDVERV
VEDLRARPPMQHVVITGRGAPPALVEAADTVTDMVPVKHAFQQGIKAQRGVEM
>Mature_213_residues
MNDNTTAQGGGTDDGGRDERHKARMVRKKEVVDAKIAAAQDERGVIVITTGNGKGKSSSGFGMVVRALGHGMRTGVVQFI
KGEQPTGEEMFLRRFPDVCDFHVMGEGYTWETQDRARDVAKAEAAWEVARGMLRDPSIGLVLFDELNIALKLHYLDVERV
VEDLRARPPMQHVVITGRGAPPALVEAADTVTDMVPVKHAFQQGIKAQRGVEM

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=50.2564102564103, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23324; Mature: 23324

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNTTAQGGGTDDGGRDERHKARMVRKKEVVDAKIAAAQDERGVIVITTGNGKGKSSSG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
FGMVVRALGHGMRTGVVQFIKGEQPTGEEMFLRRFPDVCDFHVMGEGYTWETQDRARDVA
HHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHCEEEECCCCEECCHHHHHHHH
KAEAAWEVARGMLRDPSIGLVLFDELNIALKLHYLDVERVVEDLRARPPMQHVVITGRGA
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECHHHHHHHHHCCCCCCEEEEECCCC
PPALVEAADTVTDMVPVKHAFQQGIKAQRGVEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDNTTAQGGGTDDGGRDERHKARMVRKKEVVDAKIAAAQDERGVIVITTGNGKGKSSSG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
FGMVVRALGHGMRTGVVQFIKGEQPTGEEMFLRRFPDVCDFHVMGEGYTWETQDRARDVA
HHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHCEEEECCCCEECCHHHHHHHH
KAEAAWEVARGMLRDPSIGLVLFDELNIALKLHYLDVERVVEDLRARPPMQHVVITGRGA
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECHHHHHHHHHCCCCCCEEEEECCCC
PPALVEAADTVTDMVPVKHAFQQGIKAQRGVEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]