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The map label for this gene is btuC [C]

Identifier: 73540361

GI number: 73540361

Start: 704429

End: 705436

Strand: Direct

Name: btuC [C]

Synonym: Reut_A0655

Alternate gene names: 73540361

Gene position: 704429-705436 (Clockwise)

Preceding gene: 73540360

Following gene: 73540362

Centisome position: 18.51

GC content: 69.74

Gene sequence:

>1008_bases
ATGTCTGACTTCCGGCGCGCCCTCGCGGTGTGGCTGGCGCTCGCTGCGGTCGCGGTGGCGGTGTTCCTGCTGTCGCTGGC
GTTTGGCAGCGTGCGCATGGACGCCGCGCAACTCTGGCAGGCGCTGACGGGCGCAGACACCGGCACCGCGGGCGCCATCG
TGCGCGACCTGCGCCTGCCACGTGCCGCCGCGGCATTTGCCTGCGGCGGCCTGCTGGCCTTGTCCGGTGCATTGATGCAG
GTGCTGCTGCGCAATCCGCTGGCCGAGCCCTATGTGCTGGGCGTGTCCGGCGGCGCCGCCACCGGTGCGCTCGGCGCCAT
GCTGCTGATGCTGCCGCTATGGGCCGTGCAGGCCGGCGCGGCGAGTGGTGCGTTGCTGTCGATGGTGCTGGTCGCCACGC
TCGCGCGGCGTGACCTGCTGCTTCCGCAGGTGCAGGGCGGCCACCACGAGGCCGGTGCGCGCCTGCTGCTGACGGGCGTG
ATCCTGGCCTCGGGCTGGGGCGCGCTGATTACGCTGATTCTTGCCGTTGCGCCGGAAGCGCGTCTGCGCGGCATGCTGTT
CTGGCTTACGGGCGATCTGGGCGGCACGGCTGAATATGGCGTCGCGCTGGCCATGCTGGCGCTCGCTGTCTTGCTCGCCA
TGCCGATGGCGCGCTCGCTCAATGTGATGCTCCTCGGTGAAACCGTGGCGCAGTCGTTGGGTGTTCGCGTCGGCCGCGTG
CGACTGGCCACGTTCGTGCTCGCCTCACTGTCGATTGCCGTGGCCATCACCACGGCGGGTTCGATCGGCTTTGTCGGCCT
GGTGGTGCCGCATCTGGTGCGCCTCGCATGGGGCAATGATCAGCGCCTGCTGCTGCCAGCCTCCGCGCTGCTCGGCGGGG
CGTTGTTGATGGCCGCCGATCTCATCGCACGTACCGTGATCGCGCCCGCACAGCTGCCAGTGGGCGTCATTACTGCGTTG
CTTGGCGTGCCGACCTTCCTCTACCTGCTGTTGCGGAGGCCGCGATGA

Upstream 100 bases:

>100_bases
CGACAAGAACTACCAGCTGGTCTACCCCTACAACACGCAGGGCCGGGCCGGCTATATCACGCTGGGCTGGCGCCAGAAAT
GACGGGCGGTGTGGCGCGCC

Downstream 100 bases:

>100_bases
CGCACTGGTCCGAACCCGCAGCCGCATGCTCCACGCTGTCCCTGCACGACGTGAGCCTGCGCACCGGCACGCGCGTGCTG
GTCGATGGCCTGTCGCTCGA

Product: transport system permease protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSDFRRALAVWLALAAVAVAVFLLSLAFGSVRMDAAQLWQALTGADTGTAGAIVRDLRLPRAAAAFACGGLLALSGALMQ
VLLRNPLAEPYVLGVSGGAATGALGAMLLMLPLWAVQAGAASGALLSMVLVATLARRDLLLPQVQGGHHEAGARLLLTGV
ILASGWGALITLILAVAPEARLRGMLFWLTGDLGGTAEYGVALAMLALAVLLAMPMARSLNVMLLGETVAQSLGVRVGRV
RLATFVLASLSIAVAITTAGSIGFVGLVVPHLVRLAWGNDQRLLLPASALLGGALLMAADLIARTVIAPAQLPVGVITAL
LGVPTFLYLLLRRPR

Sequences:

>Translated_335_residues
MSDFRRALAVWLALAAVAVAVFLLSLAFGSVRMDAAQLWQALTGADTGTAGAIVRDLRLPRAAAAFACGGLLALSGALMQ
VLLRNPLAEPYVLGVSGGAATGALGAMLLMLPLWAVQAGAASGALLSMVLVATLARRDLLLPQVQGGHHEAGARLLLTGV
ILASGWGALITLILAVAPEARLRGMLFWLTGDLGGTAEYGVALAMLALAVLLAMPMARSLNVMLLGETVAQSLGVRVGRV
RLATFVLASLSIAVAITTAGSIGFVGLVVPHLVRLAWGNDQRLLLPASALLGGALLMAADLIARTVIAPAQLPVGVITAL
LGVPTFLYLLLRRPR
>Mature_334_residues
SDFRRALAVWLALAAVAVAVFLLSLAFGSVRMDAAQLWQALTGADTGTAGAIVRDLRLPRAAAAFACGGLLALSGALMQV
LLRNPLAEPYVLGVSGGAATGALGAMLLMLPLWAVQAGAASGALLSMVLVATLARRDLLLPQVQGGHHEAGARLLLTGVI
LASGWGALITLILAVAPEARLRGMLFWLTGDLGGTAEYGVALAMLALAVLLAMPMARSLNVMLLGETVAQSLGVRVGRVR
LATFVLASLSIAVAITTAGSIGFVGLVVPHLVRLAWGNDQRLLLPASALLGGALLMAADLIARTVIAPAQLPVGVITALL
GVPTFLYLLLRRPR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=39.9305555555556, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790740, Length=334, Percent_Identity=36.2275449101796, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790741, Length=344, Percent_Identity=34.8837209302326, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786347, Length=298, Percent_Identity=32.8859060402685, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786805, Length=315, Percent_Identity=36.1904761904762, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786804, Length=335, Percent_Identity=34.0298507462687, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34359; Mature: 34228

Theoretical pI: Translated: 11.85; Mature: 11.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFRRALAVWLALAAVAVAVFLLSLAFGSVRMDAAQLWQALTGADTGTAGAIVRDLRLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RAAAAFACGGLLALSGALMQVLLRNPLAEPYVLGVSGGAATGALGAMLLMLPLWAVQAGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
ASGALLSMVLVATLARRDLLLPQVQGGHHEAGARLLLTGVILASGWGALITLILAVAPEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
RLRGMLFWLTGDLGGTAEYGVALAMLALAVLLAMPMARSLNVMLLGETVAQSLGVRVGRV
HHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHH
RLATFVLASLSIAVAITTAGSIGFVGLVVPHLVRLAWGNDQRLLLPASALLGGALLMAAD
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
LIARTVIAPAQLPVGVITALLGVPTFLYLLLRRPR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDFRRALAVWLALAAVAVAVFLLSLAFGSVRMDAAQLWQALTGADTGTAGAIVRDLRLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RAAAAFACGGLLALSGALMQVLLRNPLAEPYVLGVSGGAATGALGAMLLMLPLWAVQAGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
ASGALLSMVLVATLARRDLLLPQVQGGHHEAGARLLLTGVILASGWGALITLILAVAPEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
RLRGMLFWLTGDLGGTAEYGVALAMLALAVLLAMPMARSLNVMLLGETVAQSLGVRVGRV
HHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHH
RLATFVLASLSIAVAITTAGSIGFVGLVVPHLVRLAWGNDQRLLLPASALLGGALLMAAD
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
LIARTVIAPAQLPVGVITALLGVPTFLYLLLRRPR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]