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The map label for this gene is lpxP [H]

Identifier: 73539906

GI number: 73539906

Start: 224666

End: 225553

Strand: Reverse

Name: lpxP [H]

Synonym: Reut_A0200

Alternate gene names: 73539906

Gene position: 225553-224666 (Counterclockwise)

Preceding gene: 73539910

Following gene: 73539905

Centisome position: 5.93

GC content: 66.22

Gene sequence:

>888_bases
ATGACTTTCCTGTTCTGGCTGATCTCCCGCTTGCCGCTGCGCCTGCTCCAGGCCGTGGGCGGTGCGCTCGGACTGCTGGC
AGCGCGTGTGCCGGGGCGTTATGGACGTCGGCTGCGAGAGAACTTCCTGCTCGCGTTCCCGGACGCGACCGAACAGATGA
TTGCCGAAGCGGCCCGCTCGAGCGGCCGGATGATCCTGGAAATGCCGTACTTCTGGAGCCGAAAGACCATCGCCGCGCGC
CTGTACGGCTTTGACGATTACCTGTGGCCGGAACTGGAAAAGCTTCAGGCCCGCGGCAACGGCATCATCATCCTGACGCC
TCACCTGGGCTGCTTCGAGGTGCTGCCGCAATCGCATGCGCTCTTGCGCCCCGTTACCGCCCTGTTCAAGCCGCCGCACC
AGGCGTGGCTGCGCGACTGGATCGAACGCATGCGCACCCGGCCCAATTTGGCAATGGCGCCGGCAACGCCGCGCGGCGTG
CGCATGCTGGTGAAAGCGCTCAAGCGGGGCCAGGCTGTCGGCATCCTTCCTGACCAGGTACCGAGCGGCGGCGAAGGCAA
CTGGGCGCCGTTCTTCGGCAAACCCGCCTATACCATGGCGCTGGTCCACCGCCTGCAGCAACTGACCAGAGCGCCGGTTG
TCGCCATCTTCGGCGAACGGCTCCCTCGCGGCGCTGGCTACCGCGGCCATCTGTGCGTCATCAACGATGGCGGCATGTTG
CCCGAAGACCCGGCCGAAGCTGCCGCCATCATCAACCGGACCATAGAGGCACTCGTGGCCATCGCGCCCACGCAGTACCT
CTGGGGCTATCACCGCTACAAGACTCCGTCCGGCGTGCAGGACCCCGATCGGGGCACGCTGGCGGCTACCGAATCCTCCC
GCTCATGA

Upstream 100 bases:

>100_bases
GGTTAGCGGCAGGAATCCTACGGATCCTTAGCCCTGAACGACGGCTTGCTCCAGCATTGATGACCCTTTCCACAAGGGAC
CCGACATCCACCGCCACGCA

Downstream 100 bases:

>100_bases
GCCGTATCTTTACCTGGCTCGGCATCGGTCTGCTGACCGTGCTGGGCAAGCTGCCCTACCCGTTCGTCGCCCGTTTCGGC
GAGGGGCTGGGCAGCCTGCT

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTFLFWLISRLPLRLLQAVGGALGLLAARVPGRYGRRLRENFLLAFPDATEQMIAEAARSSGRMILEMPYFWSRKTIAAR
LYGFDDYLWPELEKLQARGNGIIILTPHLGCFEVLPQSHALLRPVTALFKPPHQAWLRDWIERMRTRPNLAMAPATPRGV
RMLVKALKRGQAVGILPDQVPSGGEGNWAPFFGKPAYTMALVHRLQQLTRAPVVAIFGERLPRGAGYRGHLCVINDGGML
PEDPAEAAAIINRTIEALVAIAPTQYLWGYHRYKTPSGVQDPDRGTLAATESSRS

Sequences:

>Translated_295_residues
MTFLFWLISRLPLRLLQAVGGALGLLAARVPGRYGRRLRENFLLAFPDATEQMIAEAARSSGRMILEMPYFWSRKTIAAR
LYGFDDYLWPELEKLQARGNGIIILTPHLGCFEVLPQSHALLRPVTALFKPPHQAWLRDWIERMRTRPNLAMAPATPRGV
RMLVKALKRGQAVGILPDQVPSGGEGNWAPFFGKPAYTMALVHRLQQLTRAPVVAIFGERLPRGAGYRGHLCVINDGGML
PEDPAEAAAIINRTIEALVAIAPTQYLWGYHRYKTPSGVQDPDRGTLAATESSRS
>Mature_294_residues
TFLFWLISRLPLRLLQAVGGALGLLAARVPGRYGRRLRENFLLAFPDATEQMIAEAARSSGRMILEMPYFWSRKTIAARL
YGFDDYLWPELEKLQARGNGIIILTPHLGCFEVLPQSHALLRPVTALFKPPHQAWLRDWIERMRTRPNLAMAPATPRGVR
MLVKALKRGQAVGILPDQVPSGGEGNWAPFFGKPAYTMALVHRLQQLTRAPVVAIFGERLPRGAGYRGHLCVINDGGMLP
EDPAEAAAIINRTIEALVAIAPTQYLWGYHRYKTPSGVQDPDRGTLAATESSRS

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=282, Percent_Identity=31.5602836879433, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787292, Length=290, Percent_Identity=28.6206896551724, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 32844; Mature: 32713

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLFWLISRLPLRLLQAVGGALGLLAARVPGRYGRRLRENFLLAFPDATEQMIAEAARS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCHHHHHHHHHHHC
SGRMILEMPYFWSRKTIAARLYGFDDYLWPELEKLQARGNGIIILTPHLGCFEVLPQSHA
CCCEEEECCCHHCHHHHHHHHHCCCHHHCHHHHHHHHCCCCEEEECCCCCHHHHCCCCHH
LLRPVTALFKPPHQAWLRDWIERMRTRPNLAMAPATPRGVRMLVKALKRGQAVGILPDQV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEECCCCCC
PSGGEGNWAPFFGKPAYTMALVHRLQQLTRAPVVAIFGERLPRGAGYRGHLCVINDGGML
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCC
PEDPAEAAAIINRTIEALVAIAPTQYLWGYHRYKTPSGVQDPDRGTLAATESSRS
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
TFLFWLISRLPLRLLQAVGGALGLLAARVPGRYGRRLRENFLLAFPDATEQMIAEAARS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCHHHHHHHHHHHC
SGRMILEMPYFWSRKTIAARLYGFDDYLWPELEKLQARGNGIIILTPHLGCFEVLPQSHA
CCCEEEECCCHHCHHHHHHHHHCCCHHHCHHHHHHHHCCCCEEEECCCCCHHHHCCCCHH
LLRPVTALFKPPHQAWLRDWIERMRTRPNLAMAPATPRGVRMLVKALKRGQAVGILPDQV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEECCCCCC
PSGGEGNWAPFFGKPAYTMALVHRLQQLTRAPVVAIFGERLPRGAGYRGHLCVINDGGML
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCC
PEDPAEAAAIINRTIEALVAIAPTQYLWGYHRYKTPSGVQDPDRGTLAATESSRS
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]