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The map label for this gene is aidB [H]

Identifier: 73539910

GI number: 73539910

Start: 229943

End: 231604

Strand: Reverse

Name: aidB [H]

Synonym: Reut_A0204

Alternate gene names: 73539910

Gene position: 231604-229943 (Counterclockwise)

Preceding gene: 73539917

Following gene: 73539906

Centisome position: 6.08

GC content: 67.51

Gene sequence:

>1662_bases
ATGACCGACGCCGCCACGCATCGCGTCTTCAACCAGGTGCCCGATCTCGCGCACTACAACCTGTTTGGCTGCGATCCCAT
CGTCGGCGACGCGCTGGAGCGCCTCGGTGGCGGGTGGCACGCGGCGGACCTGATGGCCTATGGCGCGCGGCTTGGTGAAC
CGGAAGTGCTCGCGTGGGGTGCCGATGCCAACCGGTACGCCCCCGAACTGCATACGTACAGCCGCACCGGCGAGCGCGTC
GACCAGGTCACGTTCCACCCGAGCTGGCATGCGCTGCTGTCCCTGCTGCGCAGCCAGCAGTTGCAGGCAATGCCGTTCGC
AGAACCGCGCGCCGGTGCCTGGATTGCGCGCACGGCCGGCTATTTCCTGCAGGCGCAAGTCGAGTCGGGATCACTGTGCC
CGATCACCATGACCTTCGCCAGTATTCCCGTGCTACGCAAGGAAACCGCGCTGTTCGCCGACCTGGAGCCGCGCCTGTAC
GCGAAGAACCATGATGCGCGCGATCTGCCGTGGCGCGACAAGACCGCGATCATGATCGGCATGGGCATGACCGAGAAGCA
AGGCGGCTCAGATGTGCGCGCCAACACGACGGTAGCCCATCCCGTGCGCGGCGAGGGCCGCGGCGCCGAATACCTGCTGA
CCGGGCACAAGTGGTTCTTCTCCGCGCCGATGTGCGACGCGCATCTGGTGGTCGCGCGCATGGGCGCCGAAGACGGCCCG
CTGTCCTGCTTCTTCGTGCCGCGCTTTCGCGACGACGGCAGCAAGAACCCGATCCAGATCCAGCGCCTGAAGGACAAGCT
CGGCAACCGCTCCAACAGCAGCAGCGAAGTGGAGTTCCGCGAGGCCAGCGGCATCCTGATCGGCGAGGAGGGCCGCGGCA
TCCCGACCATCATCGAAATGGCCACGAGCACACGGCTCGATTGCGTGATCGGCAGCGCGGCGATCCTGCGCGCAGCGTAC
GTGCAGGCGCTGCACCACACGCGCCACCGCGCCGCCTTCGGCAGCCTGCTCGCGGACCAGCCGCTGATGCGCAACGTGCT
GGCCGACCTCGCGCTCGAAAGCGAGGCCGCCACGCTGCTGATGATGGAACTGGCCCATGCGTTCGAGCACGCCGAGACCG
ATCCGCTTGCCGCCGCGTGGAAGCGCGTGGTGACGCCTGCTGCCAAGTTCTGGATCTGCAAGCGAACGATCGAGGCCACC
GGCGAGGCGATGGAAGTCTGGGGCGGCAACGGCTATGTCGAAGACGGCCCCATGGCACGCCTCTATCGCGAAGCGCCGGT
CAATTCGATCTGGGAAGGATCGGGCAACATCATGTGCCTGGACGTACTGCGCGCGATCCAGCGCACGCCCGACGACGCAG
CGCGCCTGCTGCATGACCTGTCCCGGCGCGCCGCGGCGCATCCTGCGGTTCGCGCCGAACTGGCGTCGCTGCAGGCCATG
CTCCGCGAGCCCGCGGAACAGCTTGAGGCCCATGCGCGGCGCTTTGCGCAGGGACTTGTACTGACCGCGCAGTCCGCCCT
GATGCTCGCACATGCAGACGCCGAGAATGCCGAAGCGTTCGTCGCAAGCCGGCTCGGCCGGCAGCACGGGCGCGTGTTCG
GCACGCTCGACATGGAGCCCGAAGTGCTGAAACGCGTATTCGAACGCGGCTGGACCGCGTGA

Upstream 100 bases:

>100_bases
TTGCGGCGCAGTACGTGCCATAAGGGCACCACGAGGCACTCGCGCGCCGTTCTACGTGCTCTACCATGCAATCAAAGGCC
AGCACAATCCAGGAGACATC

Downstream 100 bases:

>100_bases
AACCCGCGAAGCGACTCAGGCCTCCATCGGCTCGCGAATCCTGAGCAGTACGCGCGGCGCATAGCGGATCAGGTCATGCG
CGCGCTCGCCGATCATGATG

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTDAATHRVFNQVPDLAHYNLFGCDPIVGDALERLGGGWHAADLMAYGARLGEPEVLAWGADANRYAPELHTYSRTGERV
DQVTFHPSWHALLSLLRSQQLQAMPFAEPRAGAWIARTAGYFLQAQVESGSLCPITMTFASIPVLRKETALFADLEPRLY
AKNHDARDLPWRDKTAIMIGMGMTEKQGGSDVRANTTVAHPVRGEGRGAEYLLTGHKWFFSAPMCDAHLVVARMGAEDGP
LSCFFVPRFRDDGSKNPIQIQRLKDKLGNRSNSSSEVEFREASGILIGEEGRGIPTIIEMATSTRLDCVIGSAAILRAAY
VQALHHTRHRAAFGSLLADQPLMRNVLADLALESEAATLLMMELAHAFEHAETDPLAAAWKRVVTPAAKFWICKRTIEAT
GEAMEVWGGNGYVEDGPMARLYREAPVNSIWEGSGNIMCLDVLRAIQRTPDDAARLLHDLSRRAAAHPAVRAELASLQAM
LREPAEQLEAHARRFAQGLVLTAQSALMLAHADAENAEAFVASRLGRQHGRVFGTLDMEPEVLKRVFERGWTA

Sequences:

>Translated_553_residues
MTDAATHRVFNQVPDLAHYNLFGCDPIVGDALERLGGGWHAADLMAYGARLGEPEVLAWGADANRYAPELHTYSRTGERV
DQVTFHPSWHALLSLLRSQQLQAMPFAEPRAGAWIARTAGYFLQAQVESGSLCPITMTFASIPVLRKETALFADLEPRLY
AKNHDARDLPWRDKTAIMIGMGMTEKQGGSDVRANTTVAHPVRGEGRGAEYLLTGHKWFFSAPMCDAHLVVARMGAEDGP
LSCFFVPRFRDDGSKNPIQIQRLKDKLGNRSNSSSEVEFREASGILIGEEGRGIPTIIEMATSTRLDCVIGSAAILRAAY
VQALHHTRHRAAFGSLLADQPLMRNVLADLALESEAATLLMMELAHAFEHAETDPLAAAWKRVVTPAAKFWICKRTIEAT
GEAMEVWGGNGYVEDGPMARLYREAPVNSIWEGSGNIMCLDVLRAIQRTPDDAARLLHDLSRRAAAHPAVRAELASLQAM
LREPAEQLEAHARRFAQGLVLTAQSALMLAHADAENAEAFVASRLGRQHGRVFGTLDMEPEVLKRVFERGWTA
>Mature_552_residues
TDAATHRVFNQVPDLAHYNLFGCDPIVGDALERLGGGWHAADLMAYGARLGEPEVLAWGADANRYAPELHTYSRTGERVD
QVTFHPSWHALLSLLRSQQLQAMPFAEPRAGAWIARTAGYFLQAQVESGSLCPITMTFASIPVLRKETALFADLEPRLYA
KNHDARDLPWRDKTAIMIGMGMTEKQGGSDVRANTTVAHPVRGEGRGAEYLLTGHKWFFSAPMCDAHLVVARMGAEDGPL
SCFFVPRFRDDGSKNPIQIQRLKDKLGNRSNSSSEVEFREASGILIGEEGRGIPTIIEMATSTRLDCVIGSAAILRAAYV
QALHHTRHRAAFGSLLADQPLMRNVLADLALESEAATLLMMELAHAFEHAETDPLAAAWKRVVTPAAKFWICKRTIEATG
EAMEVWGGNGYVEDGPMARLYREAPVNSIWEGSGNIMCLDVLRAIQRTPDDAARLLHDLSRRAAAHPAVRAELASLQAML
REPAEQLEAHARRFAQGLVLTAQSALMLAHADAENAEAFVASRLGRQHGRVFGTLDMEPEVLKRVFERGWTA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=271, Percent_Identity=25.4612546125461, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226958414, Length=271, Percent_Identity=25.4612546125461, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7656849, Length=270, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557233, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4501859, Length=270, Percent_Identity=24.8148148148148, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4557231, Length=274, Percent_Identity=24.8175182481752, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI187960098, Length=274, Percent_Identity=24.8175182481752, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4501857, Length=302, Percent_Identity=23.841059602649, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=527, Percent_Identity=46.2998102466793, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786223, Length=286, Percent_Identity=24.4755244755245, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=544, Percent_Identity=28.6764705882353, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI86563383, Length=544, Percent_Identity=28.6764705882353, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17538396, Length=277, Percent_Identity=25.9927797833935, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=296, Percent_Identity=25.3378378378378, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=270, Percent_Identity=24.8148148148148, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=274, Percent_Identity=23.3576642335766, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=269, Percent_Identity=24.1635687732342, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=307, Percent_Identity=23.4527687296417, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355753, Length=267, Percent_Identity=24.7191011235955, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356377, Length=272, Percent_Identity=25.3676470588235, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363737, Length=325, Percent_Identity=20.9230769230769, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666513, Length=273, Percent_Identity=23.0769230769231, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24660351, Length=270, Percent_Identity=24.8148148148148, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60801; Mature: 60670

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAATHRVFNQVPDLAHYNLFGCDPIVGDALERLGGGWHAADLMAYGARLGEPEVLAWG
CCCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEC
ADANRYAPELHTYSRTGERVDQVTFHPSWHALLSLLRSQQLQAMPFAEPRAGAWIARTAG
CCCCCCCCHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC
YFLQAQVESGSLCPITMTFASIPVLRKETALFADLEPRLYAKNHDARDLPWRDKTAIMIG
EEEEEEECCCCCCEEEEHHHHCCHHHHHHHHEECCCCCEEECCCCCCCCCCCCCCEEEEE
MGMTEKQGGSDVRANTTVAHPVRGEGRGAEYLLTGHKWFFSAPMCDAHLVVARMGAEDGP
CCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHCCCCCCC
LSCFFVPRFRDDGSKNPIQIQRLKDKLGNRSNSSSEVEFREASGILIGEEGRGIPTIIEM
EEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCCHHHHHH
ATSTRLDCVIGSAAILRAAYVQALHHTRHRAAFGSLLADQPLMRNVLADLALESEAATLL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MMELAHAFEHAETDPLAAAWKRVVTPAAKFWICKRTIEATGEAMEVWGGNGYVEDGPMAR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
LYREAPVNSIWEGSGNIMCLDVLRAIQRTPDDAARLLHDLSRRAAAHPAVRAELASLQAM
HHHHCCCCHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LREPAEQLEAHARRFAQGLVLTAQSALMLAHADAENAEAFVASRLGRQHGRVFGTLDMEP
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCH
EVLKRVFERGWTA
HHHHHHHHCCCCC
>Mature Secondary Structure 
TDAATHRVFNQVPDLAHYNLFGCDPIVGDALERLGGGWHAADLMAYGARLGEPEVLAWG
CCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEC
ADANRYAPELHTYSRTGERVDQVTFHPSWHALLSLLRSQQLQAMPFAEPRAGAWIARTAG
CCCCCCCCHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC
YFLQAQVESGSLCPITMTFASIPVLRKETALFADLEPRLYAKNHDARDLPWRDKTAIMIG
EEEEEEECCCCCCEEEEHHHHCCHHHHHHHHEECCCCCEEECCCCCCCCCCCCCCEEEEE
MGMTEKQGGSDVRANTTVAHPVRGEGRGAEYLLTGHKWFFSAPMCDAHLVVARMGAEDGP
CCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHCCCCCCC
LSCFFVPRFRDDGSKNPIQIQRLKDKLGNRSNSSSEVEFREASGILIGEEGRGIPTIIEM
EEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCCHHHHHH
ATSTRLDCVIGSAAILRAAYVQALHHTRHRAAFGSLLADQPLMRNVLADLALESEAATLL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MMELAHAFEHAETDPLAAAWKRVVTPAAKFWICKRTIEATGEAMEVWGGNGYVEDGPMAR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
LYREAPVNSIWEGSGNIMCLDVLRAIQRTPDDAARLLHDLSRRAAAHPAVRAELASLQAM
HHHHCCCCHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LREPAEQLEAHARRFAQGLVLTAQSALMLAHADAENAEAFVASRLGRQHGRVFGTLDMEP
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCH
EVLKRVFERGWTA
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]