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The map label for this gene is xerD [H]

Identifier: 161611265

GI number: 161611265

Start: 629204

End: 630121

Strand: Reverse

Name: xerD [H]

Synonym: Reut_A0577

Alternate gene names: 161611265

Gene position: 630121-629204 (Counterclockwise)

Preceding gene: 73540284

Following gene: 73540282

Centisome position: 16.55

GC content: 66.99

Gene sequence:

>918_bases
ATGGTCGCCCTCGATGCGGCCATCGCCCCCGAACTCGATCTCGTCAGCCGTTTCTGCGACGCACTGTGGCTGGAGGATGG
CCTGTCGCGCAACACCATGGACGCCTATCGGCGCGATCTGTCGATGCTCGCGCGCTGGCTGCATCAGTCCAGCAATGGCG
GCTTGCTGGGCATCGGCGACACGGAACTGAACGCCTATTTCCTGGCGCGGCACCCCGAGACCCGCGCCTCATCCTCGAAC
CGCCGGCTCGCTGTATTCCGCCGCTTCTACCAGTGGGCACTGCGCGAGCAAATGATCGAGGCCGATCCGTGCATCCTGCT
GCGCCCCGCCAAGCAGCCGCCGCGCGTGCCCAAGACGCTAAGCGAAGCGCAGGTTGAAGCGCTGCTCGAAGCGCCCGACA
CCACCACGCCGCTCGGCCTGCGCGACCGCACCATGCTCGAGCTGATGTACGCGAGCGGACTGCGCGTGTCGGAGCTGACG
CAGATGAAAACCGTCGAGATCGGCCTGAACGAAGGCGTTGCGCGCGTGGTTGGCGGCAAGGGCGACAAGGAGCGGCTGGT
GCCTTTCGGCATGCAGGCCAGCGACTGGCTGCGCCGCTATCTGGGGAGCGCGCGCCCTGCCCTTCTTGCCGGCCGCGCGT
GCGACGCGCTATTCGTCACGCAGCGTGGCGAGGGCATGACGCGTCAGGCGTTCTGGCACCTGATCAAGCGCCATGCGCGC
GATGCCGGCATTACCGCGCCGCTGTCGCCGCATACGCTGCGGCATGCGTTTGCCACGCACCTGCTGAACCACGGCGCCGA
CCTGCGCGTGGTGCAACTGCTGCTTGGCCATGCCGATATCTCCACTACACAGATCTACACCCACGTGGCGCGCGAACGGC
TGCGCGAACTGCACCAGCAGCACCATCCACGCGGGTAA

Upstream 100 bases:

>100_bases
GCTGGCTGTTGCGCCATGAAGGCGCCATGCTGATATGAAGCGCCCGGCCGGCGCAAGCCAGACCACACGCAAGCCGCGCG
CGGTGCATGCCGATGCGGAG

Downstream 100 bases:

>100_bases
GACGAGCCGGGCTCGCCCCTGGCGCGACGAGAAGCGACAATGAGCAAAGCGAAACATATCTCCGAAACCCCGGCCACGCA
GTTCCTGCGCCGCCACAACG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MVALDAAIAPELDLVSRFCDALWLEDGLSRNTMDAYRRDLSMLARWLHQSSNGGLLGIGDTELNAYFLARHPETRASSSN
RRLAVFRRFYQWALREQMIEADPCILLRPAKQPPRVPKTLSEAQVEALLEAPDTTTPLGLRDRTMLELMYASGLRVSELT
QMKTVEIGLNEGVARVVGGKGDKERLVPFGMQASDWLRRYLGSARPALLAGRACDALFVTQRGEGMTRQAFWHLIKRHAR
DAGITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHQQHHPRG

Sequences:

>Translated_305_residues
MVALDAAIAPELDLVSRFCDALWLEDGLSRNTMDAYRRDLSMLARWLHQSSNGGLLGIGDTELNAYFLARHPETRASSSN
RRLAVFRRFYQWALREQMIEADPCILLRPAKQPPRVPKTLSEAQVEALLEAPDTTTPLGLRDRTMLELMYASGLRVSELT
QMKTVEIGLNEGVARVVGGKGDKERLVPFGMQASDWLRRYLGSARPALLAGRACDALFVTQRGEGMTRQAFWHLIKRHAR
DAGITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHQQHHPRG
>Mature_305_residues
MVALDAAIAPELDLVSRFCDALWLEDGLSRNTMDAYRRDLSMLARWLHQSSNGGLLGIGDTELNAYFLARHPETRASSSN
RRLAVFRRFYQWALREQMIEADPCILLRPAKQPPRVPKTLSEAQVEALLEAPDTTTPLGLRDRTMLELMYASGLRVSELT
QMKTVEIGLNEGVARVVGGKGDKERLVPFGMQASDWLRRYLGSARPALLAGRACDALFVTQRGEGMTRQAFWHLIKRHAR
DAGITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHQQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=57.1428571428571, Blast_Score=317, Evalue=7e-88,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=34.2372881355932, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790768, Length=170, Percent_Identity=30, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=29.6511627906977, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34274; Mature: 34274

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALDAAIAPELDLVSRFCDALWLEDGLSRNTMDAYRRDLSMLARWLHQSSNGGLLGIGD
CEECCCHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECC
TELNAYFLARHPETRASSSNRRLAVFRRFYQWALREQMIEADPCILLRPAKQPPRVPKTL
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHH
SEAQVEALLEAPDTTTPLGLRDRTMLELMYASGLRVSELTQMKTVEIGLNEGVARVVGGK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCHHHHHCCC
GDKERLVPFGMQASDWLRRYLGSARPALLAGRACDALFVTQRGEGMTRQAFWHLIKRHAR
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
DAGITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHQQ
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HHPRG
HCCCC
>Mature Secondary Structure
MVALDAAIAPELDLVSRFCDALWLEDGLSRNTMDAYRRDLSMLARWLHQSSNGGLLGIGD
CEECCCHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECC
TELNAYFLARHPETRASSSNRRLAVFRRFYQWALREQMIEADPCILLRPAKQPPRVPKTL
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHH
SEAQVEALLEAPDTTTPLGLRDRTMLELMYASGLRVSELTQMKTVEIGLNEGVARVVGGK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCHHHHHCCC
GDKERLVPFGMQASDWLRRYLGSARPALLAGRACDALFVTQRGEGMTRQAFWHLIKRHAR
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
DAGITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHQQ
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HHPRG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]