Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 71892343

GI number: 71892343

Start: 714278

End: 715384

Strand: Reverse

Name: asd [H]

Synonym: BPEN_594

Alternate gene names: 71892343

Gene position: 715384-714278 (Counterclockwise)

Preceding gene: 71892345

Following gene: 71892341

Centisome position: 90.37

GC content: 33.97

Gene sequence:

>1107_bases
ATGAAAAATATTGGGTTTGTTGGTTGGAGAGGAATGGTAGGTTCAGTATTAATGAATCGCATGAAAGAAGAAAATGATTT
TAACTATTTTCACTCAATATTTCTTTCGACATCACAAATAGGAGAACATGCTCCAAACATTCAAGCATCACAAGAATTAT
TATTACAAGACGCTTGTAATATCGATCTGCTTAATTCTTTAGATATTATTATTACGTGTCAAGGCAGCGCATATAGTAAA
ATTATTTATCCAAAATTAAGAAAAATTGGATGGACAGGATATTGGATTGATAGCGCCTCATTTTTACGAATGAATGATGA
TGCGATTATTGTTTTGGACCCTGTTAATCAAGTATTGATAAAACAAAGTATAAATAACGGTATTAAAACATTTGTAGGAG
GTAATTGCACTGTAAGTTTAATGTTAATGTCTTTAGGTGGATTGTTTGCTCATAATTTAATCGAATGGGTTTTTGCCTCT
ACGTATCAGGCAGCTTCTGGATGTGGAGCACGCGCCATGCGTGAGCTATTAATACAAATGGGCCAAGTGTACAATACAGT
AACTGATTTGTTAACGTCCCCGTCAATGGCTATTTTAGATATTGAACATATAATTACTAAATTTAGTAAAACTGATTCCT
TGTTAGTAGATTGCTTTAAAGTTCCTTTGATAGGCAACGTCATTCCGTGGATTGGTGATTATATGTATAATGGTCAAACT
CAAGAAGAATGGAAAGGTCAAGCAGAAACTAATAAAATCCTCAATACTTCTAAAATTATAACAGTAGACAGTTTATGTGT
ACGTGTGGGCTCATTACGTTGTCATAGCCAAGCATTTGTTTTAAAACTTAAAAAAGACATTTGTTTAAAAGAAATAGAAG
AATTACTCCAATCTCATAATAAATGGGTAGAAGTTATCTCAAATGATGTTACGCAATCATTAAATAAATTAACTCCTGTT
ATGGTATCCGGAACACTCAACATACCCATCGGTCGGTTACGCAAATTGCACGCAGGTAACAAATATATTTCAGCTTTTAG
CGTGGGCGATCAGTTACTTTGGGGAGCTGCTGAGCCATTACGCAGGATATTGCGTCAATTACTATAA

Upstream 100 bases:

>100_bases
CACCACGCTTTTTATAAAGTAAATTACAAAATATTATTATAAACGTATTACATCATATTACATATATTTTTGATACTTAA
TAATGACTGTGAGATTGATA

Downstream 100 bases:

>100_bases
ATTTTATTTGTTCTACAAAAAACAGATTTACAAATATATAATTTAGGAGCATTTCAAATAGAAATGCAATGCTGAAAATT
TTAAATAAATTAACTCAATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKNIGFVGWRGMVGSVLMNRMKEENDFNYFHSIFLSTSQIGEHAPNIQASQELLLQDACNIDLLNSLDIIITCQGSAYSK
IIYPKLRKIGWTGYWIDSASFLRMNDDAIIVLDPVNQVLIKQSINNGIKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFAS
TYQAASGCGARAMRELLIQMGQVYNTVTDLLTSPSMAILDIEHIITKFSKTDSLLVDCFKVPLIGNVIPWIGDYMYNGQT
QEEWKGQAETNKILNTSKIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHNKWVEVISNDVTQSLNKLTPV
MVSGTLNIPIGRLRKLHAGNKYISAFSVGDQLLWGAAEPLRRILRQLL

Sequences:

>Translated_368_residues
MKNIGFVGWRGMVGSVLMNRMKEENDFNYFHSIFLSTSQIGEHAPNIQASQELLLQDACNIDLLNSLDIIITCQGSAYSK
IIYPKLRKIGWTGYWIDSASFLRMNDDAIIVLDPVNQVLIKQSINNGIKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFAS
TYQAASGCGARAMRELLIQMGQVYNTVTDLLTSPSMAILDIEHIITKFSKTDSLLVDCFKVPLIGNVIPWIGDYMYNGQT
QEEWKGQAETNKILNTSKIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHNKWVEVISNDVTQSLNKLTPV
MVSGTLNIPIGRLRKLHAGNKYISAFSVGDQLLWGAAEPLRRILRQLL
>Mature_368_residues
MKNIGFVGWRGMVGSVLMNRMKEENDFNYFHSIFLSTSQIGEHAPNIQASQELLLQDACNIDLLNSLDIIITCQGSAYSK
IIYPKLRKIGWTGYWIDSASFLRMNDDAIIVLDPVNQVLIKQSINNGIKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFAS
TYQAASGCGARAMRELLIQMGQVYNTVTDLLTSPSMAILDIEHIITKFSKTDSLLVDCFKVPLIGNVIPWIGDYMYNGQT
QEEWKGQAETNKILNTSKIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHNKWVEVISNDVTQSLNKLTPV
MVSGTLNIPIGRLRKLHAGNKYISAFSVGDQLLWGAAEPLRRILRQLL

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=63.4877384196185, Blast_Score=503, Evalue=1e-144,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 41134; Mature: 41134

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIGFVGWRGMVGSVLMNRMKEENDFNYFHSIFLSTSQIGEHAPNIQASQELLLQDACN
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
IDLLNSLDIIITCQGSAYSKIIYPKLRKIGWTGYWIDSASFLRMNDDAIIVLDPVNQVLI
CEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCEEEEECCHHHHHH
KQSINNGIKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFASTYQAASGCGARAMRELLIQM
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GQVYNTVTDLLTSPSMAILDIEHIITKFSKTDSLLVDCFKVPLIGNVIPWIGDYMYNGQT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QEEWKGQAETNKILNTSKIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHN
HHHHCCCHHHHHHCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KWVEVISNDVTQSLNKLTPVMVSGTLNIPIGRLRKLHAGNKYISAFSVGDQLLWGAAEPL
HHHHHHHHHHHHHHHHCCCEEEECEECCCHHHHHHHHCCCCEEEEHHCCHHHHHCCHHHH
RRILRQLL
HHHHHHHC
>Mature Secondary Structure
MKNIGFVGWRGMVGSVLMNRMKEENDFNYFHSIFLSTSQIGEHAPNIQASQELLLQDACN
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
IDLLNSLDIIITCQGSAYSKIIYPKLRKIGWTGYWIDSASFLRMNDDAIIVLDPVNQVLI
CEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCEEEEECCHHHHHH
KQSINNGIKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFASTYQAASGCGARAMRELLIQM
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GQVYNTVTDLLTSPSMAILDIEHIITKFSKTDSLLVDCFKVPLIGNVIPWIGDYMYNGQT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QEEWKGQAETNKILNTSKIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHN
HHHHCCCHHHHHHCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KWVEVISNDVTQSLNKLTPVMVSGTLNIPIGRLRKLHAGNKYISAFSVGDQLLWGAAEPL
HHHHHHHHHHHHHHHHCCCEEEECEECCCHHHHHHHHCCCCEEEEHHCCHHHHHCCHHHH
RRILRQLL
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]