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The map label for this gene is aroK

Identifier: 71892341

GI number: 71892341

Start: 711475

End: 712038

Strand: Reverse

Name: aroK

Synonym: BPEN_592

Alternate gene names: 71892341

Gene position: 712038-711475 (Counterclockwise)

Preceding gene: 71892343

Following gene: 71892340

Centisome position: 89.94

GC content: 34.93

Gene sequence:

>564_bases
ATGAAGAAATCATTTTCATATAATAATATGTTAAAAAAAAATAATATTTTTTTAATCGGCCCTATGGGGGCTGGGAAAAG
TACCATCGGGCGTCAACTAGCAAATCAATTAAATATGGAGTTTTTTGATTCTGATCAAGAAATTGAGACTCGTACCGGAG
CAAATATTAGCTGGGTTTTCGACGTAGAAGGAGAAGAGAGATTCCGCGATCGTGAAGAAAAAATTATCGATGAATTAACA
AAAAAACAGGGAATTATATTAGCTACCGGAGGTGGTTCTGTTAAATCTCACATAACACGGAATAATCTTTCCGATCGTGG
ATTCGTGGTATACTTAGAAACGACTATTGAAAAACAATTAATTCGAACGCAACATGATAAAAGGCGTCCATTGCTGAGAT
CCTCATCAGCATCAGGAAATACTCGCGACTTACTACAAGTATTAGCAAAAGAACGTAATCCGTTGTACGAGGAAATTGCA
GATATAAGAATTTCTACAGACGAACAAAATGTCAGGGTTGTCGTTAATAAAATTATTATTCTTCGTAAAAAAAGCAGTTT
ATGA

Upstream 100 bases:

>100_bases
TACATTTATAAAAAATAAGATGATTTTAATGCTTTATATTTTTTGTATCTGTACGTTTATTGATCAGTTGGGTCTTCATA
TAAAGTGATGAAACGATAAA

Downstream 100 bases:

>100_bases
CGTTTGTCATTATAAATTCATCATTTTAATATTAAAAGCTTTTATAATTTTGTTATGGAAAAAATTATCATAAAATTAGA
AAAAAGAAGCTATCCAATTA

Product: shikimate kinase I

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKKSFSYNNMLKKNNIFLIGPMGAGKSTIGRQLANQLNMEFFDSDQEIETRTGANISWVFDVEGEERFRDREEKIIDELT
KKQGIILATGGGSVKSHITRNNLSDRGFVVYLETTIEKQLIRTQHDKRRPLLRSSSASGNTRDLLQVLAKERNPLYEEIA
DIRISTDEQNVRVVVNKIIILRKKSSL

Sequences:

>Translated_187_residues
MKKSFSYNNMLKKNNIFLIGPMGAGKSTIGRQLANQLNMEFFDSDQEIETRTGANISWVFDVEGEERFRDREEKIIDELT
KKQGIILATGGGSVKSHITRNNLSDRGFVVYLETTIEKQLIRTQHDKRRPLLRSSSASGNTRDLLQVLAKERNPLYEEIA
DIRISTDEQNVRVVVNKIIILRKKSSL
>Mature_187_residues
MKKSFSYNNMLKKNNIFLIGPMGAGKSTIGRQLANQLNMEFFDSDQEIETRTGANISWVFDVEGEERFRDREEKIIDELT
KKQGIILATGGGSVKSHITRNNLSDRGFVVYLETTIEKQLIRTQHDKRRPLLRSSSASGNTRDLLQVLAKERNPLYEEIA
DIRISTDEQNVRVVVNKIIILRKKSSL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=170, Percent_Identity=72.3529411764706, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=32.0987654320988, Blast_Score=87, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=126, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_BLOPB (Q492A4)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278075.1
- ProteinModelPortal:   Q492A4
- SMR:   Q492A4
- STRING:   Q492A4
- GeneID:   3563065
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_592
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- BioCyc:   CBLO291272:BPEN_592-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR003593
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100
- SMART:   SM00382

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 21385; Mature: 21385

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 45-45 BINDING 69-69 BINDING 91-91 BINDING 129-129 BINDING 152-152 BINDING 169-169

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSFSYNNMLKKNNIFLIGPMGAGKSTIGRQLANQLNMEFFDSDQEIETRTGANISWVF
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEE
DVEGEERFRDREEKIIDELTKKQGIILATGGGSVKSHITRNNLSDRGFVVYLETTIEKQL
ECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCCCCEEEEEEHHHHHHH
IRTQHDKRRPLLRSSSASGNTRDLLQVLAKERNPLYEEIADIRISTDEQNVRVVVNKIII
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCEECCCCCCHHHEEEHHHE
LRKKSSL
EEECCCC
>Mature Secondary Structure
MKKSFSYNNMLKKNNIFLIGPMGAGKSTIGRQLANQLNMEFFDSDQEIETRTGANISWVF
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEE
DVEGEERFRDREEKIIDELTKKQGIILATGGGSVKSHITRNNLSDRGFVVYLETTIEKQL
ECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCCCCEEEEEEHHHHHHH
IRTQHDKRRPLLRSSSASGNTRDLLQVLAKERNPLYEEIADIRISTDEQNVRVVVNKIII
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCEECCCCCCHHHEEEHHHE
LRKKSSL
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA