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The map label for this gene is rnc

Identifier: 71892313

GI number: 71892313

Start: 669812

End: 670501

Strand: Reverse

Name: rnc

Synonym: BPEN_560

Alternate gene names: 71892313

Gene position: 670501-669812 (Counterclockwise)

Preceding gene: 71892314

Following gene: 71892312

Centisome position: 84.7

GC content: 33.77

Gene sequence:

>690_bases
ATGTTAGTTAATGCATTGCAAGAAAAACTTGGTTATATTTTTAATCGATATGACTTATTATTACAAGCGCTAACTCATAG
AAGCTCTAGCAATCAACACAATGAAAGACTAGAATTTTTGGGCGACGCCATATTAAACTATGTAATAGCTAATTTGTTAT
ATCATAGGTTTCCTCATATTAGTGAAGGAGGTATGAGTAGAATGCGTGCAAATTTGGTACGCGAAAATACATTGGCAACA
CTAGCACGAGAATTTAATTTAGGAGATTATCTACAATTAGGACAAGGAGAACTAAAAAGCGGGGGATATCAACGTGAATC
CATTTTGGCCAATACAATAGAAGCGTTGATAGGCGGTATATTTTTAGATAGTAATATTCAAACTATTGAAATATTAATTA
TTAATTGGTATAAAATTCGTATAGATCATATGGATCCTTATGCTTCTTATGATACACAAAAAGATCCAAAAACTCGTCTG
CAAGAATATATGCAACGCCGTCGTTTGCCGTTACCTGTATATTGGATTAATCAAATAATTGGAGAGGCGCACAATCAAAT
ATTTACGATAAATTGTCAAGTTAGTGAATTAACACAACCGATTATTGGATGCGGTTCTAGTCGGCGTAGAGCTGAACAAA
ATGCAGCAGCAAAAGTTTTAGAGGCACTAGAACATAACCAAAACATATGA

Upstream 100 bases:

>100_bases
TAAAATTATTTTATTACATTTGTTGTAATCAATCTGGTTAAAATTGATTACAAAAAATTTTCTCCATGAACATTGGAAGA
ATATATAATACATAAATATT

Downstream 100 bases:

>100_bases
TTTAATGACGCGGTCATAGACCGTAAATTGCTTAATATATTATTAGGATCTTAAACAAAATTAACTCATGTTATTAAGTT
TATTCAATAAATAAACATAC

Product: RNase III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHISEGGMSRMRANLVRENTLAT
LAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGIFLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRL
QEYMQRRRLPLPVYWINQIIGEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI

Sequences:

>Translated_229_residues
MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHISEGGMSRMRANLVRENTLAT
LAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGIFLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRL
QEYMQRRRLPLPVYWINQIIGEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI
>Mature_229_residues
MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHISEGGMSRMRANLVRENTLAT
LAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGIFLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRL
QEYMQRRRLPLPVYWINQIIGEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030234, Length=231, Percent_Identity=26.8398268398268, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI155030236, Length=231, Percent_Identity=26.8398268398268, Blast_Score=84, Evalue=7e-17,
Organism=Escherichia coli, GI1788920, Length=224, Percent_Identity=67.4107142857143, Blast_Score=307, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI17506883, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193202651, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323895, Length=98, Percent_Identity=38.7755102040816, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17137682, Length=236, Percent_Identity=25.4237288135593, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_BLOPB (Q492D1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278047.1
- STRING:   Q492D1
- GeneID:   3562922
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_560
- eggNOG:   COG0571
- HOGENOM:   HBG744556
- OMA:   THRSFAG
- BioCyc:   CBLO291272:BPEN_560-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 26359; Mature: 26359

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SEGGMSRMRANLVRENTLATLAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHH
FLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRLQEYMQRRRLPLPVYWINQII
HCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
GEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI
HHHCCEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SEGGMSRMRANLVRENTLATLAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHH
FLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRLQEYMQRRRLPLPVYWINQII
HCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
GEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI
HHHCCEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA