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The map label for this gene is pdxJ

Identifier: 71892312

GI number: 71892312

Start: 668433

End: 669167

Strand: Reverse

Name: pdxJ

Synonym: BPEN_559

Alternate gene names: 71892312

Gene position: 669167-668433 (Counterclockwise)

Preceding gene: 71892313

Following gene: 71892311

Centisome position: 84.53

GC content: 32.24

Gene sequence:

>735_bases
ATGTCAAATTTATTATTAGGTGTAAATATTGATCATATCGCAACATTACGTAACGCAAGAAATACTACGTATCCTGATCC
TATATATGCTGCATTCATTGCAGAACAATCAGGAGCAGATAGCATTACTATACATTTAAGAGAAGACCGTCGTCACATTA
CAGATCGAGATGTCGAAATGTTATGTAAAACCATACAAACATCTATGAACTTAGAAATAGCAGCAACAGATGAAATGATT
AATATCGCATGTACGTTAAAACCACATTGTTGTTGCTTAGTACCGGAAAGGCGTCAAGAACTTACAACTGAAGGTGGCTT
AGATATAATTAATAAAGCAAATAAATTACAAGATATAATATTTAAACTTACTGAAGCTGGAATTAGAGTTTCATTGTTTA
TTGATCCTAATGAACAACAAATTAGTGTTGCCTATAATATAGGTGCGCCTTATATAGAACTACATACCGGAATGTATTCT
CATGCTACAGATGCAACAACTCAAAATTTAGAATATAAACGTATCAAAAAAAGTGTGCAATACGCTGTCAATAAGGGTTT
AAAAGTTAATGCTGGACATGGTCTTAATTATTATAACGTACGACCTATTGCGATGTTACCAGGAATACAAGAATTAAATA
TAGGACATGCTATAATTAGCCGATCAATATTTTGTGGATTACCTAAAGCTATTCAAGATATGAAGAAATTGATACAAGAC
TCAAGAAGAGGTTAA

Upstream 100 bases:

>100_bases
ATTAAATAGAAACAACAAAAAATACATTTAAAAAGAAATATATATAATTTATATTTATAGTCGATGACTATCAAGTAACT
ATATTTAAGGCATACATATA

Downstream 100 bases:

>100_bases
TAGTGATTCACGGAATCGGAATAGATATCGTTGATATTAGGAAAATAAAAAAAATAATAACACATAGTGGAGATAAGTTA
GCTACGCGTATACTTAGTAA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSNLLLGVNIDHIATLRNARNTTYPDPIYAAFIAEQSGADSITIHLREDRRHITDRDVEMLCKTIQTSMNLEIAATDEMI
NIACTLKPHCCCLVPERRQELTTEGGLDIINKANKLQDIIFKLTEAGIRVSLFIDPNEQQISVAYNIGAPYIELHTGMYS
HATDATTQNLEYKRIKKSVQYAVNKGLKVNAGHGLNYYNVRPIAMLPGIQELNIGHAIISRSIFCGLPKAIQDMKKLIQD
SRRG

Sequences:

>Translated_244_residues
MSNLLLGVNIDHIATLRNARNTTYPDPIYAAFIAEQSGADSITIHLREDRRHITDRDVEMLCKTIQTSMNLEIAATDEMI
NIACTLKPHCCCLVPERRQELTTEGGLDIINKANKLQDIIFKLTEAGIRVSLFIDPNEQQISVAYNIGAPYIELHTGMYS
HATDATTQNLEYKRIKKSVQYAVNKGLKVNAGHGLNYYNVRPIAMLPGIQELNIGHAIISRSIFCGLPKAIQDMKKLIQD
SRRG
>Mature_243_residues
SNLLLGVNIDHIATLRNARNTTYPDPIYAAFIAEQSGADSITIHLREDRRHITDRDVEMLCKTIQTSMNLEIAATDEMIN
IACTLKPHCCCLVPERRQELTTEGGLDIINKANKLQDIIFKLTEAGIRVSLFIDPNEQQISVAYNIGAPYIELHTGMYSH
ATDATTQNLEYKRIKKSVQYAVNKGLKVNAGHGLNYYNVRPIAMLPGIQELNIGHAIISRSIFCGLPKAIQDMKKLIQDS
RRG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=242, Percent_Identity=60.3305785123967, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_BLOPB (Q492D2)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278046.1
- ProteinModelPortal:   Q492D2
- SMR:   Q492D2
- STRING:   Q492D2
- GeneID:   3562921
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_559
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   CBLO291272:BPEN_559-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 27306; Mature: 27175

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: ACT_SITE 45-45 ACT_SITE 72-72 ACT_SITE 193-193 BINDING 9-9 BINDING 20-20 BINDING 47-47 BINDING 52-52 BINDING 102-102 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLLLGVNIDHIATLRNARNTTYPDPIYAAFIAEQSGADSITIHLREDRRHITDRDVEM
CCCEEEECCHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCEEEEEEECCCCCCCCHHHHH
LCKTIQTSMNLEIAATDEMINIACTLKPHCCCLVPERRQELTTEGGLDIINKANKLQDII
HHHHHHHHCCEEEEECCCEEEEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHH
FKLTEAGIRVSLFIDPNEQQISVAYNIGAPYIELHTGMYSHATDATTQNLEYKRIKKSVQ
HHHHHCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
YAVNKGLKVNAGHGLNYYNVRPIAMLPGIQELNIGHAIISRSIFCGLPKAIQDMKKLIQD
HHHCCCEEEECCCCCCEEECCEEHCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
SRRG
HCCC
>Mature Secondary Structure 
SNLLLGVNIDHIATLRNARNTTYPDPIYAAFIAEQSGADSITIHLREDRRHITDRDVEM
CCEEEECCHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCEEEEEEECCCCCCCCHHHHH
LCKTIQTSMNLEIAATDEMINIACTLKPHCCCLVPERRQELTTEGGLDIINKANKLQDII
HHHHHHHHCCEEEEECCCEEEEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHH
FKLTEAGIRVSLFIDPNEQQISVAYNIGAPYIELHTGMYSHATDATTQNLEYKRIKKSVQ
HHHHHCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
YAVNKGLKVNAGHGLNYYNVRPIAMLPGIQELNIGHAIISRSIFCGLPKAIQDMKKLIQD
HHHCCCEEEECCCCCCEEECCEEHCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
SRRG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA