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The map label for this gene is lepB [H]

Identifier: 71892314

GI number: 71892314

Start: 670628

End: 671623

Strand: Reverse

Name: lepB [H]

Synonym: BPEN_561

Alternate gene names: 71892314

Gene position: 671623-670628 (Counterclockwise)

Preceding gene: 71892315

Following gene: 71892313

Centisome position: 84.84

GC content: 28.92

Gene sequence:

>996_bases
ATGATTAACGCATTTTCTTTGATCTTAGCAATTATTACAGGAATATCAGGTATTTTCTGGAGTATAAAAAAATTATATAC
ATTAATGTATGATCGCGATCAACATAAAAAAATATTCCTTCAACAATCAACCAAGACTTATCAACAATCAAAAAATGCTT
ATTCATTGATAATCTCATATTGTTCAATAATTTCTGAATTTATATCCTCAATTTTTCCGATATTATTATTAGTATTTATA
ATACGATCATTTGTTTTTGAACCATTCCGAATACCTTCTGGATCCATGATGCCTACTTTGTTAATAGGAGATTTTATTTT
AGTAAAAAAATTTATATATGGTATTAAAAATCCTATTACTCAAAAAACATTAATTAATACTGGACATCCAAAACGTGGAG
ATATAATAGTGTTTAAGTATCCTAAAAATCCTGAACTAAATTATATTAAACGAGTAATTGGAGAGCCAGGAGACAAAGTA
ATCTATAACATTATTACTAAACAATTAATAATATATGTGAATCATGTTAATAATATTGCATGTATACAACCATTACCCAT
TGTTTATAGCAATGTTGTTCCTAGTAATTTTATTCAAGTATTTGATAATGACGTAGACGGAAGGGTTAATTCTTCCTTTA
TTCAAATAGGACCGCATCAAAAATGTCCTCATGGAATTCGACTCATTCAAACTACAGAATCGTTCAATGGAATAGAACAC
AATATCTTAACAATGATACCGCCTGGTGATCAAAACTTAATAAAAATGTATGATCAACATACAAAACACTTAATATCTGA
GTGGCTAGTGCCCGCAGGTGAGTATTTTGTAATGGGAGATAACAGGGATAACAGCGCAGATAGTCGTTATTGGGGATTTG
TTCCTGAACGCAATATAATAGGAAAAGCAATAATAATTTGGATGAATATAAAGAAACAACAAGAAGGAATATGGCCAATT
AGTATCCAATTCCATAGAATTGGTAATATACAATAA

Upstream 100 bases:

>100_bases
ACGTATGAAACAAATAGGCAATGTTAATTTACCCCATACTGTATTTCTAGCTGTCTTTGATGTCAATAACAATAAAAAAT
AACTAAAGGATTTTATTTGT

Downstream 100 bases:

>100_bases
GATATTCATATTCTCTAATCATAGTTTAAAATTATTTTATTACATTTGTTGTAATCAATCTGGTTAAAATTGATTACAAA
AAATTTTCTCCATGAACATT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MINAFSLILAIITGISGIFWSIKKLYTLMYDRDQHKKIFLQQSTKTYQQSKNAYSLIISYCSIISEFISSIFPILLLVFI
IRSFVFEPFRIPSGSMMPTLLIGDFILVKKFIYGIKNPITQKTLINTGHPKRGDIIVFKYPKNPELNYIKRVIGEPGDKV
IYNIITKQLIIYVNHVNNIACIQPLPIVYSNVVPSNFIQVFDNDVDGRVNSSFIQIGPHQKCPHGIRLIQTTESFNGIEH
NILTMIPPGDQNLIKMYDQHTKHLISEWLVPAGEYFVMGDNRDNSADSRYWGFVPERNIIGKAIIIWMNIKKQQEGIWPI
SIQFHRIGNIQ

Sequences:

>Translated_331_residues
MINAFSLILAIITGISGIFWSIKKLYTLMYDRDQHKKIFLQQSTKTYQQSKNAYSLIISYCSIISEFISSIFPILLLVFI
IRSFVFEPFRIPSGSMMPTLLIGDFILVKKFIYGIKNPITQKTLINTGHPKRGDIIVFKYPKNPELNYIKRVIGEPGDKV
IYNIITKQLIIYVNHVNNIACIQPLPIVYSNVVPSNFIQVFDNDVDGRVNSSFIQIGPHQKCPHGIRLIQTTESFNGIEH
NILTMIPPGDQNLIKMYDQHTKHLISEWLVPAGEYFVMGDNRDNSADSRYWGFVPERNIIGKAIIIWMNIKKQQEGIWPI
SIQFHRIGNIQ
>Mature_331_residues
MINAFSLILAIITGISGIFWSIKKLYTLMYDRDQHKKIFLQQSTKTYQQSKNAYSLIISYCSIISEFISSIFPILLLVFI
IRSFVFEPFRIPSGSMMPTLLIGDFILVKKFIYGIKNPITQKTLINTGHPKRGDIIVFKYPKNPELNYIKRVIGEPGDKV
IYNIITKQLIIYVNHVNNIACIQPLPIVYSNVVPSNFIQVFDNDVDGRVNSSFIQIGPHQKCPHGIRLIQTTESFNGIEH
NILTMIPPGDQNLIKMYDQHTKHLISEWLVPAGEYFVMGDNRDNSADSRYWGFVPERNIIGKAIIIWMNIKKQQEGIWPI
SIQFHRIGNIQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=331, Percent_Identity=47.7341389728097, Blast_Score=326, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 38078; Mature: 38078

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAFSLILAIITGISGIFWSIKKLYTLMYDRDQHKKIFLQQSTKTYQQSKNAYSLIISY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHCCHHHHHHHHH
CSIISEFISSIFPILLLVFIIRSFVFEPFRIPSGSMMPTLLIGDFILVKKFIYGIKNPIT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
QKTLINTGHPKRGDIIVFKYPKNPELNYIKRVIGEPGDKVIYNIITKQLIIYVNHVNNIA
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCEE
CIQPLPIVYSNVVPSNFIQVFDNDVDGRVNSSFIQIGPHQKCPHGIRLIQTTESFNGIEH
EECCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCC
NILTMIPPGDQNLIKMYDQHTKHLISEWLVPAGEYFVMGDNRDNSADSRYWGFVPERNII
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCCCCCC
GKAIIIWMNIKKQQEGIWPISIQFHRIGNIQ
CEEEEEEEECCHHHCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MINAFSLILAIITGISGIFWSIKKLYTLMYDRDQHKKIFLQQSTKTYQQSKNAYSLIISY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHCCHHHHHHHHH
CSIISEFISSIFPILLLVFIIRSFVFEPFRIPSGSMMPTLLIGDFILVKKFIYGIKNPIT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
QKTLINTGHPKRGDIIVFKYPKNPELNYIKRVIGEPGDKVIYNIITKQLIIYVNHVNNIA
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCEE
CIQPLPIVYSNVVPSNFIQVFDNDVDGRVNSSFIQIGPHQKCPHGIRLIQTTESFNGIEH
EECCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCC
NILTMIPPGDQNLIKMYDQHTKHLISEWLVPAGEYFVMGDNRDNSADSRYWGFVPERNII
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCCCCCC
GKAIIIWMNIKKQQEGIWPISIQFHRIGNIQ
CEEEEEEEECCHHHCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6311837; 9278503; 2202591; 1618816; 1546969; 8394311; 2551889; 9823901 [H]