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The map label for this gene is thrS [H]

Identifier: 71892130

GI number: 71892130

Start: 429232

End: 430458

Strand: Direct

Name: thrS [H]

Synonym: BPEN_362

Alternate gene names: 71892130

Gene position: 429232-430458 (Clockwise)

Preceding gene: 71892129

Following gene: 71892131

Centisome position: 54.22

GC content: 31.3

Gene sequence:

>1227_bases
ATGTCACAAGTACCTAAAAAAAATGATCATCGCAACCTTGCGAAACAACTACACTTATACCATACACAAAAAGATGCTCC
CGGTATGGTATTTTGGCATCAAAATGGATGGATTTTATTACAAGAATTAAAAAAAATTATAAGAACGCAACTTAAAGAAT
ATAAATATCAAGAAGTGAAAAGTCCTACCATGATTAATCATACATTATGGAAAAAAACAGGCCATTGGGATAATTATCAT
GAACATATATTTACTACTTCTTCAGAAAGTCATGAATATTGTATTAAACCGATGAATTGCCCAGGACATATTCAAATTTT
TAATCAAGGTATTAAGTCTTATAAAGATTTGCCTTATCGTATAGCTGAATTTGGAAATTGTCATAGAAACGAACCATCTG
GGTCTTTACATGGACTCATGAGAACACGCGAATTTACCCAAGATGATGGTCATATTTTTTGTACAAAAACACAAATATTC
GACGAATTAAACCACTGTATCAAAATGATGTATGATATATATAATACATTCGGTTTTAAAACGATTTTGGTAAAATTATC
TACTCGTCCTGCAAAGCGAATTGGTACAGATTCGATATGGGATACGGCAGAACAACATTTATCTACTGTACTTCAGCATA
ATAATATCTCATTTCAATATCAACCTAATGATGGTGCATTTTATGGTCCTAAAATAGAATTTGCTTTACTTGATTCTTTA
GATAGAACTTGGCAATGTGGTACAATACAATTGGATTTTTCTTTACCAAATCTATTAAACGCACGGTATATTGATCGTCA
TAATAGTCGCGTAGTCCCCGTAATGATTCACAGAGCAATTCTTGGTTCCATGGAACGATTTATTGGTTTAATAACAGAAG
AATACGCAGGATTTTTCCCGACGTGGTTAGCCCCGACACAGGTTGTGCTCATGAATGTCACTGATCAACAATCTGAATAT
GTTTCTGTTATAGAAAAAAAGCTAATAAATAAAAAAATAAGAACGAAAGTAGACTTGAGAAATGAGAAAATAGGATTTAA
AATTCGTTATTATACCTTGCAACGCATACCTTATATGTTGATTTGCGGAAATAAAGAAATGAATCAAAATACAGTAGCTA
TACGTACATATCGAGGTCAAACATTAAAAAACTGTAATATTGATATATTTATAAAAAAATTACTTTGTGAAATTAACAGT
TACAGTCTTTATCAAATGGAGGAATAA

Upstream 100 bases:

>100_bases
ATTTCTAAGTTTTACTGGATTAAAAACAGTAAAATTAAAAATTGCACATACTTGTAGTCTCTACAGAACAAAAAATAAAT
AATGTATAACTCACAAAAAT

Downstream 100 bases:

>100_bases
CATATTATTAAATTCGCAAAAAAAATACAATCAATACGACTAAATCGTATTAACAGAGAAATTAGTGCTGTAAAAGTCCG
ACTAACCGGAGTAGACGGAA

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSQVPKKNDHRNLAKQLHLYHTQKDAPGMVFWHQNGWILLQELKKIIRTQLKEYKYQEVKSPTMINHTLWKKTGHWDNYH
EHIFTTSSESHEYCIKPMNCPGHIQIFNQGIKSYKDLPYRIAEFGNCHRNEPSGSLHGLMRTREFTQDDGHIFCTKTQIF
DELNHCIKMMYDIYNTFGFKTILVKLSTRPAKRIGTDSIWDTAEQHLSTVLQHNNISFQYQPNDGAFYGPKIEFALLDSL
DRTWQCGTIQLDFSLPNLLNARYIDRHNSRVVPVMIHRAILGSMERFIGLITEEYAGFFPTWLAPTQVVLMNVTDQQSEY
VSVIEKKLINKKIRTKVDLRNEKIGFKIRYYTLQRIPYMLICGNKEMNQNTVAIRTYRGQTLKNCNIDIFIKKLLCEINS
YSLYQMEE

Sequences:

>Translated_408_residues
MSQVPKKNDHRNLAKQLHLYHTQKDAPGMVFWHQNGWILLQELKKIIRTQLKEYKYQEVKSPTMINHTLWKKTGHWDNYH
EHIFTTSSESHEYCIKPMNCPGHIQIFNQGIKSYKDLPYRIAEFGNCHRNEPSGSLHGLMRTREFTQDDGHIFCTKTQIF
DELNHCIKMMYDIYNTFGFKTILVKLSTRPAKRIGTDSIWDTAEQHLSTVLQHNNISFQYQPNDGAFYGPKIEFALLDSL
DRTWQCGTIQLDFSLPNLLNARYIDRHNSRVVPVMIHRAILGSMERFIGLITEEYAGFFPTWLAPTQVVLMNVTDQQSEY
VSVIEKKLINKKIRTKVDLRNEKIGFKIRYYTLQRIPYMLICGNKEMNQNTVAIRTYRGQTLKNCNIDIFIKKLLCEINS
YSLYQMEE
>Mature_407_residues
SQVPKKNDHRNLAKQLHLYHTQKDAPGMVFWHQNGWILLQELKKIIRTQLKEYKYQEVKSPTMINHTLWKKTGHWDNYHE
HIFTTSSESHEYCIKPMNCPGHIQIFNQGIKSYKDLPYRIAEFGNCHRNEPSGSLHGLMRTREFTQDDGHIFCTKTQIFD
ELNHCIKMMYDIYNTFGFKTILVKLSTRPAKRIGTDSIWDTAEQHLSTVLQHNNISFQYQPNDGAFYGPKIEFALLDSLD
RTWQCGTIQLDFSLPNLLNARYIDRHNSRVVPVMIHRAILGSMERFIGLITEEYAGFFPTWLAPTQVVLMNVTDQQSEYV
SVIEKKLINKKIRTKVDLRNEKIGFKIRYYTLQRIPYMLICGNKEMNQNTVAIRTYRGQTLKNCNIDIFIKKLLCEINSY
SLYQMEE

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38202255, Length=405, Percent_Identity=38.0246913580247, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI38570111, Length=389, Percent_Identity=38.8174807197943, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI20070344, Length=419, Percent_Identity=35.5608591885441, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1788013, Length=402, Percent_Identity=66.4179104477612, Blast_Score=602, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI71984192, Length=396, Percent_Identity=37.8787878787879, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI71984184, Length=396, Percent_Identity=37.8787878787879, Blast_Score=305, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6322112, Length=393, Percent_Identity=39.1857506361323, Blast_Score=307, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6322654, Length=393, Percent_Identity=37.4045801526718, Blast_Score=281, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24583839, Length=395, Percent_Identity=38.4810126582278, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24583842, Length=395, Percent_Identity=38.4810126582278, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI28574141, Length=395, Percent_Identity=38.4810126582278, Blast_Score=309, Evalue=3e-84,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 48046; Mature: 47915

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00024 HEMOPEXIN ; PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVPKKNDHRNLAKQLHLYHTQKDAPGMVFWHQNGWILLQELKKIIRTQLKEYKYQEVK
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC
SPTMINHTLWKKTGHWDNYHEHIFTTSSESHEYCIKPMNCPGHIQIFNQGIKSYKDLPYR
CCCCCHHHHHHCCCCCCCCHHEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHH
IAEFGNCHRNEPSGSLHGLMRTREFTQDDGHIFCTKTQIFDELNHCIKMMYDIYNTFGFK
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCE
TILVKLSTRPAKRIGTDSIWDTAEQHLSTVLQHNNISFQYQPNDGAFYGPKIEFALLDSL
EEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCEEEEHHHHCC
DRTWQCGTIQLDFSLPNLLNARYIDRHNSRVVPVMIHRAILGSMERFIGLITEEYAGFFP
CCCCCCCEEEEECCCCCHHCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TWLAPTQVVLMNVTDQQSEYVSVIEKKLINKKIRTKVDLRNEKIGFKIRYYTLQRIPYML
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEE
ICGNKEMNQNTVAIRTYRGQTLKNCNIDIFIKKLLCEINSYSLYQMEE
EECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
SQVPKKNDHRNLAKQLHLYHTQKDAPGMVFWHQNGWILLQELKKIIRTQLKEYKYQEVK
CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC
SPTMINHTLWKKTGHWDNYHEHIFTTSSESHEYCIKPMNCPGHIQIFNQGIKSYKDLPYR
CCCCCHHHHHHCCCCCCCCHHEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHH
IAEFGNCHRNEPSGSLHGLMRTREFTQDDGHIFCTKTQIFDELNHCIKMMYDIYNTFGFK
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCE
TILVKLSTRPAKRIGTDSIWDTAEQHLSTVLQHNNISFQYQPNDGAFYGPKIEFALLDSL
EEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCEEEEHHHHCC
DRTWQCGTIQLDFSLPNLLNARYIDRHNSRVVPVMIHRAILGSMERFIGLITEEYAGFFP
CCCCCCCEEEEECCCCCHHCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TWLAPTQVVLMNVTDQQSEYVSVIEKKLINKKIRTKVDLRNEKIGFKIRYYTLQRIPYML
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEE
ICGNKEMNQNTVAIRTYRGQTLKNCNIDIFIKKLLCEINSYSLYQMEE
EECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA