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The map label for this gene is infC [H]

Identifier: 71892131

GI number: 71892131

Start: 430465

End: 431004

Strand: Direct

Name: infC [H]

Synonym: BPEN_363

Alternate gene names: 71892131

Gene position: 430465-431004 (Clockwise)

Preceding gene: 71892130

Following gene: 71892132

Centisome position: 54.38

GC content: 33.33

Gene sequence:

>540_bases
ATTAAATTCGCAAAAAAAATACAATCAATACGACTAAATCGTATTAACAGAGAAATTAGTGCTGTAAAAGTCCGACTAAC
CGGAGTAGACGGAAAACAAATTGGTGTAGTCAGTTTACATGAAGCGCTGAAGCAATCCGAAGACATCGGTCTTGATTTAG
TTGAAGTTAGCCCTAATTCCGATCCACCTGTGTGTAGAATTATGAACTACGGTAAATTTTTATACGAAAAGAACAAATCT
ACAAAAGAACAAAAGAAAAAACAAAAGGTGATTCACGTCAAAGAAATAAAATTTAGACCAAGTACTGATGAAGGAGATTA
TCAAGTCAAATTGCGTAATTTAATTAAATTCCTTAATGAAGGAGATAAAGTCAAAATCACCTTACGTTTTAGAGGAGGGG
AATTGGTGCACCACCAACTTGGAGCAAAAATATTATACCGAATACGTCACGAATTGCATGAATTAACAACAGTAGAATTT
TTTTCTAATAAAATTGAAGGGCGCCAAATGACTATGATTTTAGCGCCAAAAAAGAAATAA

Upstream 100 bases:

>100_bases
AGGTCAAACATTAAAAAACTGTAATATTGATATATTTATAAAAAAATTACTTTGTGAAATTAACAGTTACAGTCTTTATC
AAATGGAGGAATAACATATT

Downstream 100 bases:

>100_bases
TAATTCACATTATCTATACATCAGCGTCAACGCATATAATGAAAAATTATAGGGGTTAATTTATGCCTAAAATTAAAACA
CTTCAAGCAGCTAGTAAACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKFAKKIQSIRLNRINREISAVKVRLTGVDGKQIGVVSLHEALKQSEDIGLDLVEVSPNSDPPVCRIMNYGKFLYEKNKS
TKEQKKKQKVIHVKEIKFRPSTDEGDYQVKLRNLIKFLNEGDKVKITLRFRGGELVHHQLGAKILYRIRHELHELTTVEF
FSNKIEGRQMTMILAPKKK

Sequences:

>Translated_179_residues
MKFAKKIQSIRLNRINREISAVKVRLTGVDGKQIGVVSLHEALKQSEDIGLDLVEVSPNSDPPVCRIMNYGKFLYEKNKS
TKEQKKKQKVIHVKEIKFRPSTDEGDYQVKLRNLIKFLNEGDKVKITLRFRGGELVHHQLGAKILYRIRHELHELTTVEF
FSNKIEGRQMTMILAPKKK
>Mature_179_residues
MKFAKKIQSIRLNRINREISAVKVRLTGVDGKQIGVVSLHEALKQSEDIGLDLVEVSPNSDPPVCRIMNYGKFLYEKNKS
TKEQKKKQKVIHVKEIKFRPSTDEGDYQVKLRNLIKFLNEGDKVKITLRFRGGELVHHQLGAKILYRIRHELHELTTVEF
FSNKIEGRQMTMILAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=179, Percent_Identity=68.7150837988827, Blast_Score=238, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20751; Mature: 20751

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAKKIQSIRLNRINREISAVKVRLTGVDGKQIGVVSLHEALKQSEDIGLDLVEVSPNS
CCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCC
DPPVCRIMNYGKFLYEKNKSTKEQKKKQKVIHVKEIKFRPSTDEGDYQVKLRNLIKFLNE
CCCEEEHHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEECCCCCCCCEEEHHHHHHHHHCC
GDKVKITLRFRGGELVHHQLGAKILYRIRHELHELTTVEFFSNKIEGRQMTMILAPKKK
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKFAKKIQSIRLNRINREISAVKVRLTGVDGKQIGVVSLHEALKQSEDIGLDLVEVSPNS
CCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCC
DPPVCRIMNYGKFLYEKNKSTKEQKKKQKVIHVKEIKFRPSTDEGDYQVKLRNLIKFLNE
CCCEEEHHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEECCCCCCCCEEEHHHHHHHHHCC
GDKVKITLRFRGGELVHHQLGAKILYRIRHELHELTTVEFFSNKIEGRQMTMILAPKKK
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405963 [H]