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The map label for this gene is kdsA [H]

Identifier: 71892129

GI number: 71892129

Start: 426212

End: 427045

Strand: Direct

Name: kdsA [H]

Synonym: BPEN_361

Alternate gene names: 71892129

Gene position: 426212-427045 (Clockwise)

Preceding gene: 71892128

Following gene: 71892130

Centisome position: 53.84

GC content: 33.93

Gene sequence:

>834_bases
ATGCAACAATTAATAGTCAATATCTCTGACATAAAAGTATCCAACAATTTACCGTTCGTATTATTTGGAGGAATGAATGT
TTTGGAGTCACGAGACATAACCATGAAAGTTTGCGAACATTATGCAAAAATAACTCATAAACTCAATATACCTCATATAT
TCAAAGCATCTTTCGACAAAGCAAATCGTTCATCAATTGACTCATATCGTGGACCAGGATTAGAAGAAGGGTTGCGTTTA
TTTCAAGAATTACAGGAAATATTTGGAGTTAAACTTATGACTGATGTACATGAAATTTACCAAGTAAAAACTGTATCGGA
AGTAGTAGACGTACTACAGATTCCTGCGTTTTTAGCTCGTCAAACTGATTTAATTGCATCCATTGCGCAGACTGGTATGC
CAATTAATATAAAAAAACCACAATATATGAGTCCTACACAAATCATACATATTGTTAAGAAATGTCGCTCATTTAGCAAT
AAAAACATTATTTTATGTGAACGAGGCACTGTATTTGGTTATGATAACTTGGTAGTGGATATGCTAGGATTCAACGTAAT
GAATCACGTTTCCAAAGGTTGTCCAATAATAGTAGATGTCACGCATGCTTTGCAAAAACGTAATCCATTAAGTCCTATTT
CTGGAGGAAGAAACAGACAAATTTATGATATGGCTAGAGCCAGCACAGCAGTAGGCATAGCCGGATTATTTCTTGAGGCG
CACCCTAATCCTCATCGTGCTAAATGTGATGGATCTTCTGCATTACCTTTAAATCAATTAGAAAATTTTTTAACACAAAT
AAAATCTATTGATGAACTAGTCAAATCTTTTTAA

Upstream 100 bases:

>100_bases
GTAACTGATACACTATGGTTGTCTTTAATAAATATTAAAGCTATTACTAATAAATTTACAGTTTTATAATATTAAAATTA
AAAATATTGGATGTATATGC

Downstream 100 bases:

>100_bases
AATCTTACACTAGACTAAAATTTTAAATTAATAATAAAAAATTTTCTGATTGAAAATCATTTTTTTAAAAAACCTGAATT
TTTTATATTTCATATAAATA

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MQQLIVNISDIKVSNNLPFVLFGGMNVLESRDITMKVCEHYAKITHKLNIPHIFKASFDKANRSSIDSYRGPGLEEGLRL
FQELQEIFGVKLMTDVHEIYQVKTVSEVVDVLQIPAFLARQTDLIASIAQTGMPINIKKPQYMSPTQIIHIVKKCRSFSN
KNIILCERGTVFGYDNLVVDMLGFNVMNHVSKGCPIIVDVTHALQKRNPLSPISGGRNRQIYDMARASTAVGIAGLFLEA
HPNPHRAKCDGSSALPLNQLENFLTQIKSIDELVKSF

Sequences:

>Translated_277_residues
MQQLIVNISDIKVSNNLPFVLFGGMNVLESRDITMKVCEHYAKITHKLNIPHIFKASFDKANRSSIDSYRGPGLEEGLRL
FQELQEIFGVKLMTDVHEIYQVKTVSEVVDVLQIPAFLARQTDLIASIAQTGMPINIKKPQYMSPTQIIHIVKKCRSFSN
KNIILCERGTVFGYDNLVVDMLGFNVMNHVSKGCPIIVDVTHALQKRNPLSPISGGRNRQIYDMARASTAVGIAGLFLEA
HPNPHRAKCDGSSALPLNQLENFLTQIKSIDELVKSF
>Mature_277_residues
MQQLIVNISDIKVSNNLPFVLFGGMNVLESRDITMKVCEHYAKITHKLNIPHIFKASFDKANRSSIDSYRGPGLEEGLRL
FQELQEIFGVKLMTDVHEIYQVKTVSEVVDVLQIPAFLARQTDLIASIAQTGMPINIKKPQYMSPTQIIHIVKKCRSFSN
KNIILCERGTVFGYDNLVVDMLGFNVMNHVSKGCPIIVDVTHALQKRNPLSPISGGRNRQIYDMARASTAVGIAGLFLEA
HPNPHRAKCDGSSALPLNQLENFLTQIKSIDELVKSF

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=277, Percent_Identity=63.898916967509, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30963; Mature: 30963

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLIVNISDIKVSNNLPFVLFGGMNVLESRDITMKVCEHYAKITHKLNIPHIFKASFDK
CCCEEEEEEEEEECCCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCC
ANRSSIDSYRGPGLEEGLRLFQELQEIFGVKLMTDVHEIYQVKTVSEVVDVLQIPAFLAR
CCHHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTDLIASIAQTGMPINIKKPQYMSPTQIIHIVKKCRSFSNKNIILCERGTVFGYDNLVVD
HHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEECCHHHHHH
MLGFNVMNHVSKGCPIIVDVTHALQKRNPLSPISGGRNRQIYDMARASTAVGIAGLFLEA
HHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEC
HPNPHRAKCDGSSALPLNQLENFLTQIKSIDELVKSF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQLIVNISDIKVSNNLPFVLFGGMNVLESRDITMKVCEHYAKITHKLNIPHIFKASFDK
CCCEEEEEEEEEECCCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCC
ANRSSIDSYRGPGLEEGLRLFQELQEIFGVKLMTDVHEIYQVKTVSEVVDVLQIPAFLAR
CCHHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTDLIASIAQTGMPINIKKPQYMSPTQIIHIVKKCRSFSNKNIILCERGTVFGYDNLVVD
HHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEECCHHHHHH
MLGFNVMNHVSKGCPIIVDVTHALQKRNPLSPISGGRNRQIYDMARASTAVGIAGLFLEA
HHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEC
HPNPHRAKCDGSSALPLNQLENFLTQIKSIDELVKSF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]