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The map label for this gene is ispA [H]

Identifier: 71892019

GI number: 71892019

Start: 276175

End: 277095

Strand: Reverse

Name: ispA [H]

Synonym: BPEN_245

Alternate gene names: 71892019

Gene position: 277095-276175 (Counterclockwise)

Preceding gene: 71892021

Following gene: 71892018

Centisome position: 35.0

GC content: 34.2

Gene sequence:

>921_bases
ATGCTTATGATTGATTTTGCTAATGAGTTACGTGAAAGCCATCAACGAGTAGACGAAGCTATTAGTCGTTATTTGATTAT
GTTTCTTAAACAAGATGTATCTCTCCTTATGCAAGCAATACGTTATAGTGTTCTGTTAGGAGGAAAACGGTTACGTCCTT
TTTTAGTTTATCAAACAGGTAAATTATTTGGTATTAGATCGTCAAATCTTAATGCTCCAGCAGCAGCCATTGAATGCATA
CATGCTTATTCTTTAATTCATGATGATTTACCTATTATGGATAATGATAAACTGCGTAGAGGGCATCCAACATGTCATGT
CAAATTTGGAGAATCTATTGCTGTTTTAGCAGGTGATGCTCTACATACATTGGCTTTTACCATTCTTTCAGAAGCACATA
TGCCAACTATCACAGATCAAGATCGTTTAAAAATGATTGCTACATTAGCTTCTGCCAGCGGAGCTAATGGAATGTGCTTA
GGTCAGTCTTTAGATTTAATTAATAAAAATAATAAAAATATATCAGCCACACAGTTAGAAACCATATATCAGTACAAAAC
AGGATCGTTAATTCGAGCTGCAGTTCGCATTGGAGCGTTAGCAGCAGGCAACAAAAGCTGCGACGACGTATTGTCATTTC
TAGACCACTATGCTACAACTATAGGTTTAGCTTTTCAAATACAAGACGACATTATAGATATTTCACATGCATATGATCAG
AAAAAAAAACACAGTATGCAATCGCAACATAACGATGTCAACAACACTTATCCAAAAATATTAGGATTAAGCACAGCTCG
CACTAAAGCTCAAGATTTATATTGTGAGTCATTAACATCTTTAAAATACATTGCGAAATTAGGCTATAACGTTAATATTT
TATCTGCATTTTCGCGTTATATTATTAAACGTAACAACTAA

Upstream 100 bases:

>100_bases
ATATTTTTATTATGTAATATTATTATATACTGTGTATGTCATTTAAATACACATATCTAATAGTGTTTATTTTATGATTT
TATGGTATTAGTACAATACT

Downstream 100 bases:

>100_bases
AATTACATAAATAAACAATATTAAATAAATTTAATATGAACTGTAATTCAAATAAATACCCCATATTAGGTTTAATCAAT
ACTCCTAAAGAATTAAGACA

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLMIDFANELRESHQRVDEAISRYLIMFLKQDVSLLMQAIRYSVLLGGKRLRPFLVYQTGKLFGIRSSNLNAPAAAIECI
HAYSLIHDDLPIMDNDKLRRGHPTCHVKFGESIAVLAGDALHTLAFTILSEAHMPTITDQDRLKMIATLASASGANGMCL
GQSLDLINKNNKNISATQLETIYQYKTGSLIRAAVRIGALAAGNKSCDDVLSFLDHYATTIGLAFQIQDDIIDISHAYDQ
KKKHSMQSQHNDVNNTYPKILGLSTARTKAQDLYCESLTSLKYIAKLGYNVNILSAFSRYIIKRNN

Sequences:

>Translated_306_residues
MLMIDFANELRESHQRVDEAISRYLIMFLKQDVSLLMQAIRYSVLLGGKRLRPFLVYQTGKLFGIRSSNLNAPAAAIECI
HAYSLIHDDLPIMDNDKLRRGHPTCHVKFGESIAVLAGDALHTLAFTILSEAHMPTITDQDRLKMIATLASASGANGMCL
GQSLDLINKNNKNISATQLETIYQYKTGSLIRAAVRIGALAAGNKSCDDVLSFLDHYATTIGLAFQIQDDIIDISHAYDQ
KKKHSMQSQHNDVNNTYPKILGLSTARTKAQDLYCESLTSLKYIAKLGYNVNILSAFSRYIIKRNN
>Mature_306_residues
MLMIDFANELRESHQRVDEAISRYLIMFLKQDVSLLMQAIRYSVLLGGKRLRPFLVYQTGKLFGIRSSNLNAPAAAIECI
HAYSLIHDDLPIMDNDKLRRGHPTCHVKFGESIAVLAGDALHTLAFTILSEAHMPTITDQDRLKMIATLASASGANGMCL
GQSLDLINKNNKNISATQLETIYQYKTGSLIRAAVRIGALAAGNKSCDDVLSFLDHYATTIGLAFQIQDDIIDISHAYDQ
KKKHSMQSQHNDVNNTYPKILGLSTARTKAQDLYCESLTSLKYIAKLGYNVNILSAFSRYIIKRNN

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=304, Percent_Identity=51.9736842105263, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1789578, Length=232, Percent_Identity=29.7413793103448, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 34070; Mature: 34070

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMIDFANELRESHQRVDEAISRYLIMFLKQDVSLLMQAIRYSVLLGGKRLRPFLVYQTG
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
KLFGIRSSNLNAPAAAIECIHAYSLIHDDLPIMDNDKLRRGHPTCHVKFGESIAVLAGDA
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECHH
LHTLAFTILSEAHMPTITDQDRLKMIATLASASGANGMCLGQSLDLINKNNKNISATQLE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCCCCCHHHHH
TIYQYKTGSLIRAAVRIGALAAGNKSCDDVLSFLDHYATTIGLAFQIQDDIIDISHAYDQ
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHH
KKKHSMQSQHNDVNNTYPKILGLSTARTKAQDLYCESLTSLKYIAKLGYNVNILSAFSRY
HHHHHHHHHCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IIKRNN
HHCCCC
>Mature Secondary Structure
MLMIDFANELRESHQRVDEAISRYLIMFLKQDVSLLMQAIRYSVLLGGKRLRPFLVYQTG
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
KLFGIRSSNLNAPAAAIECIHAYSLIHDDLPIMDNDKLRRGHPTCHVKFGESIAVLAGDA
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECHH
LHTLAFTILSEAHMPTITDQDRLKMIATLASASGANGMCLGQSLDLINKNNKNISATQLE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCCCCCHHHHH
TIYQYKTGSLIRAAVRIGALAAGNKSCDDVLSFLDHYATTIGLAFQIQDDIIDISHAYDQ
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHH
KKKHSMQSQHNDVNNTYPKILGLSTARTKAQDLYCESLTSLKYIAKLGYNVNILSAFSRY
HHHHHHHHHCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IIKRNN
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2089044; 9278503 [H]