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The map label for this gene is xerD [H]

Identifier: 68535950

GI number: 68535950

Start: 1043491

End: 1044390

Strand: Direct

Name: xerD [H]

Synonym: jk0873

Alternate gene names: 68535950

Gene position: 1043491-1044390 (Clockwise)

Preceding gene: 68535949

Following gene: 68535951

Centisome position: 42.38

GC content: 65.33

Gene sequence:

>900_bases
TTGAGCGCAGAAGCCAACCGCAAGCTCGTCACGGCCTACATCCGGCATCTGAAGACCGAGCGCGATGTTTCCGTACACAC
TCTGTCGAACTACCAGCGCGACCTCGACCGCTACCTGGTGTGGCTAGGCTCCAAGGCACTGCAGGAAGTCACCGCCACAG
ACATCGAGGATCACCTGGTTTACCTCCGCAAGGATCTTAACCTCGCGGCATCCTCCGCTGCCCGCGGGCTGGCTGCGATC
CGCGGCCTACACTCCTTCGCTCATGCCGATGGCCGTCTGCCCTTCGACGTTGCGGTCGACGTACCCACGCCCTCGCAGGG
CGGTTCCATCCCGAAGGCCCTAAGCCTGGCACAGGTCGAGGCTTTGCTGAACGCGGTGCCGGCGGGCGACGGGGCGTCAC
AAATAAACATCCGCGACCGTGCGCTGCTCGAGATGCTCTACTCGACCGGCGCGCGCATCACCGAGCTACTAGACCTCGAC
GTCGACGACCTCGACCGAGAACAGCGCGTGCTGCTGGTGCGTGGCAAGGGCGGCAAGGAGCGCATCGTGCCCCTCGGGCG
CCCCGCGCTGCAGGCGGTGGAGCGCTACCTGGTGAGGGCGCGGCCGAGCCTGAACAAGAAAGGCAGCCCCGCGCTGTTCC
TCAACAACCGCGGGGCGCGCCTGGGTCGCCAATCGGGCTTCAAGATCGTTTCGCAGGCGGCGGAGGCGGCGGGGCTGGAG
CACGTCTCGCCGCACAGCCTCCGACACAGCTTCGCCACGCACCTATTGGAGGGCGGCGCAGATATTCGCGTGGTGCAGGA
ACTTCTCGGCCACGCTAGCGTGGCCACCACGCAGATTTACACCAAGGTCAGCCCTGAGCACTTGAGGGAAATTTGGGCCT
CATCTCACCCCCGTACCTAG

Upstream 100 bases:

>100_bases
GCCGGGACGTTTCAGAGCCATTCAACTACCACTCCGGCCTCGCCGATCGCCGCTCCGCCAGCGCGGAAGCCAAGCCCGGC
ACGGACATGAAGTTCATCCG

Downstream 100 bases:

>100_bases
TGCGCCTGATAATCTCTAGGGTGTAATTAAAGGCTATTTATCACAATCAAGGGAAAGGGCTTGACGGGATCGCCGATGTC
ACGTTCACAGTCACACGCGG

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSAEANRKLVTAYIRHLKTERDVSVHTLSNYQRDLDRYLVWLGSKALQEVTATDIEDHLVYLRKDLNLAASSAARGLAAI
RGLHSFAHADGRLPFDVAVDVPTPSQGGSIPKALSLAQVEALLNAVPAGDGASQINIRDRALLEMLYSTGARITELLDLD
VDDLDREQRVLLVRGKGGKERIVPLGRPALQAVERYLVRARPSLNKKGSPALFLNNRGARLGRQSGFKIVSQAAEAAGLE
HVSPHSLRHSFATHLLEGGADIRVVQELLGHASVATTQIYTKVSPEHLREIWASSHPRT

Sequences:

>Translated_299_residues
MSAEANRKLVTAYIRHLKTERDVSVHTLSNYQRDLDRYLVWLGSKALQEVTATDIEDHLVYLRKDLNLAASSAARGLAAI
RGLHSFAHADGRLPFDVAVDVPTPSQGGSIPKALSLAQVEALLNAVPAGDGASQINIRDRALLEMLYSTGARITELLDLD
VDDLDREQRVLLVRGKGGKERIVPLGRPALQAVERYLVRARPSLNKKGSPALFLNNRGARLGRQSGFKIVSQAAEAAGLE
HVSPHSLRHSFATHLLEGGADIRVVQELLGHASVATTQIYTKVSPEHLREIWASSHPRT
>Mature_298_residues
SAEANRKLVTAYIRHLKTERDVSVHTLSNYQRDLDRYLVWLGSKALQEVTATDIEDHLVYLRKDLNLAASSAARGLAAIR
GLHSFAHADGRLPFDVAVDVPTPSQGGSIPKALSLAQVEALLNAVPAGDGASQINIRDRALLEMLYSTGARITELLDLDV
DDLDREQRVLLVRGKGGKERIVPLGRPALQAVERYLVRARPSLNKKGSPALFLNNRGARLGRQSGFKIVSQAAEAAGLEH
VSPHSLRHSFATHLLEGGADIRVVQELLGHASVATTQIYTKVSPEHLREIWASSHPRT

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=40.6143344709898, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=37.2013651877133, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790768, Length=189, Percent_Identity=35.4497354497354, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=30.939226519337, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32666; Mature: 32534

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEANRKLVTAYIRHLKTERDVSVHTLSNYQRDLDRYLVWLGSKALQEVTATDIEDHLV
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRKDLNLAASSAARGLAAIRGLHSFAHADGRLPFDVAVDVPTPSQGGSIPKALSLAQVE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
ALLNAVPAGDGASQINIRDRALLEMLYSTGARITELLDLDVDDLDREQRVLLVRGKGGKE
HHHHHCCCCCCCCEECHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCCEEEEEECCCCCC
RIVPLGRPALQAVERYLVRARPSLNKKGSPALFLNNRGARLGRQSGFKIVSQAAEAAGLE
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
HVSPHSLRHSFATHLLEGGADIRVVQELLGHASVATTQIYTKVSPEHLREIWASSHPRT
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAEANRKLVTAYIRHLKTERDVSVHTLSNYQRDLDRYLVWLGSKALQEVTATDIEDHLV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRKDLNLAASSAARGLAAIRGLHSFAHADGRLPFDVAVDVPTPSQGGSIPKALSLAQVE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
ALLNAVPAGDGASQINIRDRALLEMLYSTGARITELLDLDVDDLDREQRVLLVRGKGGKE
HHHHHCCCCCCCCEECHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCCEEEEEECCCCCC
RIVPLGRPALQAVERYLVRARPSLNKKGSPALFLNNRGARLGRQSGFKIVSQAAEAAGLE
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
HVSPHSLRHSFATHLLEGGADIRVVQELLGHASVATTQIYTKVSPEHLREIWASSHPRT
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]