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The map label for this gene is nudF [H]

Identifier: 68535949

GI number: 68535949

Start: 1042838

End: 1043494

Strand: Direct

Name: nudF [H]

Synonym: jk0872

Alternate gene names: 68535949

Gene position: 1042838-1043494 (Clockwise)

Preceding gene: 68535948

Following gene: 68535950

Centisome position: 42.35

GC content: 65.14

Gene sequence:

>657_bases
ATGAGCAACGACAGCACCCCGTACCGCGTTGTAGATAGCGAACTGCTGCTGGACGCGCCGATCATCGGCGTGCGCCGCGA
TACGATCACCACCGCCACCGGCGAGGCGAAGCGCGAGATCGTGGAGCACTTCTCCGCCGTCGCCGTCGCCGCTGTGCGCG
ATAACCACGTGATGATGATCCGCCAGTATCGCCATGGCGTGGGCCGCCAACTGTGGGAGATTCCCGCCGGCCTGCTGGAC
CTGGTGGGGGAGGATCCCCTGGAAGCCGCCCGCCGGGAGCTAGCAGAGGAAGCAGGGCTGCGCGCCCACACCTGGCACCT
GCTGGGGGATGTCGTGACCTCCCCGGGTTTCAGTGAGGAAATGTGCCGGATCTACCTGGCCGAAGACTTGGACGATGACC
TCTCCGGCCTCGACCTACCCGAGGCAGAATTCGAAGAGGCGGAGATTGAAACCCGCTGGGTGCCGATCCCCGAAGCCATC
GAATGGGTGCAGACGGGCAAGGTCGAAAACTCCATCGCCACCATCGCCCTGCTGCACCTGGCCGCAGGTACCCGCCGGGA
CGTTTCAGAGCCATTCAACTACCACTCCGGCCTCGCCGATCGCCGCTCCGCCAGCGCGGAAGCCAAGCCCGGCACGGACA
TGAAGTTCATCCGTTGA

Upstream 100 bases:

>100_bases
CCACCCGCTGTTCCAGGGACTGGTGGACGCTGCGCTGAAGCACCAGGCTGGGCGCTCCTAATTCAGCGCGCCTAGGCTTC
CACTCCTAAACTGGGGAGTC

Downstream 100 bases:

>100_bases
GCGCAGAAGCCAACCGCAAGCTCGTCACGGCCTACATCCGGCATCTGAAGACCGAGCGCGATGTTTCCGTACACACTCTG
TCGAACTACCAGCGCGACCT

Product: putative NTP pyrophosphohydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSNDSTPYRVVDSELLLDAPIIGVRRDTITTATGEAKREIVEHFSAVAVAAVRDNHVMMIRQYRHGVGRQLWEIPAGLLD
LVGEDPLEAARRELAEEAGLRAHTWHLLGDVVTSPGFSEEMCRIYLAEDLDDDLSGLDLPEAEFEEAEIETRWVPIPEAI
EWVQTGKVENSIATIALLHLAAGTRRDVSEPFNYHSGLADRRSASAEAKPGTDMKFIR

Sequences:

>Translated_218_residues
MSNDSTPYRVVDSELLLDAPIIGVRRDTITTATGEAKREIVEHFSAVAVAAVRDNHVMMIRQYRHGVGRQLWEIPAGLLD
LVGEDPLEAARRELAEEAGLRAHTWHLLGDVVTSPGFSEEMCRIYLAEDLDDDLSGLDLPEAEFEEAEIETRWVPIPEAI
EWVQTGKVENSIATIALLHLAAGTRRDVSEPFNYHSGLADRRSASAEAKPGTDMKFIR
>Mature_217_residues
SNDSTPYRVVDSELLLDAPIIGVRRDTITTATGEAKREIVEHFSAVAVAAVRDNHVMMIRQYRHGVGRQLWEIPAGLLDL
VGEDPLEAARRELAEEAGLRAHTWHLLGDVVTSPGFSEEMCRIYLAEDLDDDLSGLDLPEAEFEEAEIETRWVPIPEAIE
WVQTGKVENSIATIALLHLAAGTRRDVSEPFNYHSGLADRRSASAEAKPGTDMKFIR

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 24214; Mature: 24083

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDSTPYRVVDSELLLDAPIIGVRRDTITTATGEAKREIVEHFSAVAVAAVRDNHVMMI
CCCCCCCEEEECHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEHH
RQYRHGVGRQLWEIPAGLLDLVGEDPLEAARRELAEEAGLRAHTWHLLGDVVTSPGFSEE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHH
MCRIYLAEDLDDDLSGLDLPEAEFEEAEIETRWVPIPEAIEWVQTGKVENSIATIALLHL
HHHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHH
AAGTRRDVSEPFNYHSGLADRRSASAEAKPGTDMKFIR
HCCCCCCHHCCHHHHCCCCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNDSTPYRVVDSELLLDAPIIGVRRDTITTATGEAKREIVEHFSAVAVAAVRDNHVMMI
CCCCCCEEEECHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEHH
RQYRHGVGRQLWEIPAGLLDLVGEDPLEAARRELAEEAGLRAHTWHLLGDVVTSPGFSEE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHH
MCRIYLAEDLDDDLSGLDLPEAEFEEAEIETRWVPIPEAIEWVQTGKVENSIATIALLHL
HHHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHH
AAGTRRDVSEPFNYHSGLADRRSASAEAKPGTDMKFIR
HCCCCCCHHCCHHHHCCCCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]