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The map label for this gene is coaE

Identifier: 68535900

GI number: 68535900

Start: 981491

End: 982075

Strand: Direct

Name: coaE

Synonym: jk0825

Alternate gene names: 68535900

Gene position: 981491-982075 (Clockwise)

Preceding gene: 68535898

Following gene: 68535902

Centisome position: 39.86

GC content: 62.56

Gene sequence:

>585_bases
ATGATCACAATTGGGCTGACTGGTGGAATCGGATCCGGCAAGTCAACCGTTTCTTCGCGGTTGGCGGAGCTCGGTGCTTT
TATTGTTGACGCCGACCTGGTGGCGCGCGAGATCGTCGAACCAGGTCAGCCAGCTTTGGCCGAGCTGGCGGATGCCTTTG
ACGGGGTGCTGAACCCCGACGGCACGTTAAACCGGGGGGAACTAGCCCGGCAGGCCTTTGCCACGCCGGAGGCGACGGAG
AAGCTGAACGCGATCACCCACCCGCGCATTCGTGCCCGCACCGAAGAGCTGTTTAAGCAGGGGAGGGAGTCCGGCGCGCA
GGTGCTCGTTTACGACATGCCGCTGCTTATCGAAAACGGTGAGGTCGACAAGGTCGATCACGTGTTGGTGGTGGACGCTC
CCGACGAGCTGCGCATCGACCGCCTAGTGCAACACCGTGGTTTGGACGAAAATGACGCCCGCCGCCGCATTGCCGCCCAG
ATCGACCGCGCGACCCGCCTCAATGCGGCGGACACGGTTCTGGATAATTCCGGAACCGTGGAACAGCTACTCGAGCAGGT
CGACGGCTTCTGGGGCGGGCTCTAA

Upstream 100 bases:

>100_bases
GGCCTGCGCATGGAGTTCGGCAACCTTGCCGCCAGCTACTACCAGTGCCGCCTGGCCGGAAACACTCTGACCGGCTCGCT
GTAGGCGCTAGCATGGCCTC

Downstream 100 bases:

>100_bases
AGCGCTACCAGAACCGGGGGATACCGGCCCCGAATATCGGCGGCAGGCCATCGGCGACAACCGTCTCCGGGAAGATGAAT
AGCCCCACCGCGTCGCGGTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MITIGLTGGIGSGKSTVSSRLAELGAFIVDADLVAREIVEPGQPALAELADAFDGVLNPDGTLNRGELARQAFATPEATE
KLNAITHPRIRARTEELFKQGRESGAQVLVYDMPLLIENGEVDKVDHVLVVDAPDELRIDRLVQHRGLDENDARRRIAAQ
IDRATRLNAADTVLDNSGTVEQLLEQVDGFWGGL

Sequences:

>Translated_194_residues
MITIGLTGGIGSGKSTVSSRLAELGAFIVDADLVAREIVEPGQPALAELADAFDGVLNPDGTLNRGELARQAFATPEATE
KLNAITHPRIRARTEELFKQGRESGAQVLVYDMPLLIENGEVDKVDHVLVVDAPDELRIDRLVQHRGLDENDARRRIAAQ
IDRATRLNAADTVLDNSGTVEQLLEQVDGFWGGL
>Mature_194_residues
MITIGLTGGIGSGKSTVSSRLAELGAFIVDADLVAREIVEPGQPALAELADAFDGVLNPDGTLNRGELARQAFATPEATE
KLNAITHPRIRARTEELFKQGRESGAQVLVYDMPLLIENGEVDKVDHVLVVDAPDELRIDRLVQHRGLDENDARRRIAAQ
IDRATRLNAADTVLDNSGTVEQLLEQVDGFWGGL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=181, Percent_Identity=38.6740331491713, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI191252795, Length=181, Percent_Identity=38.6740331491713, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI110227607, Length=195, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI110227605, Length=195, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI110227603, Length=195, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI110227601, Length=195, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI205277394, Length=195, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=42.0454545454545, Blast_Score=126, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=37.8238341968912, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25143409, Length=186, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=38.7755102040816, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24644728, Length=184, Percent_Identity=35.8695652173913, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24658602, Length=194, Percent_Identity=28.8659793814433, Blast_Score=94, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_CORJK (Q4JW20)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250605.1
- ProteinModelPortal:   Q4JW20
- SMR:   Q4JW20
- STRING:   Q4JW20
- GeneID:   3432190
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0825
- NMPDR:   fig|306537.3.peg.1913
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   PRK14734
- BioCyc:   CJEI306537:JK0825-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 20974; Mature: 20974

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIGLTGGIGSGKSTVSSRLAELGAFIVDADLVAREIVEPGQPALAELADAFDGVLNPD
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GTLNRGELARQAFATPEATEKLNAITHPRIRARTEELFKQGRESGAQVLVYDMPLLIENG
CCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEECC
EVDKVDHVLVVDAPDELRIDRLVQHRGLDENDARRRIAAQIDRATRLNAADTVLDNSGTV
CCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCH
EQLLEQVDGFWGGL
HHHHHHHHHHHCCC
>Mature Secondary Structure
MITIGLTGGIGSGKSTVSSRLAELGAFIVDADLVAREIVEPGQPALAELADAFDGVLNPD
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GTLNRGELARQAFATPEATEKLNAITHPRIRARTEELFKQGRESGAQVLVYDMPLLIENG
CCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEECC
EVDKVDHVLVVDAPDELRIDRLVQHRGLDENDARRRIAAQIDRATRLNAADTVLDNSGTV
CCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCH
EQLLEQVDGFWGGL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA