Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 66767106

GI number: 66767106

Start: 926819

End: 927538

Strand: Reverse

Name: ompR [H]

Synonym: XC_0770

Alternate gene names: 66767106

Gene position: 927538-926819 (Counterclockwise)

Preceding gene: 66767108

Following gene: 66767105

Centisome position: 18.01

GC content: 66.11

Gene sequence:

>720_bases
ATGGACATGCAACAACCCTGCGTTCTTGTGGTCGACGACGACCCCGACCTGCGCAAGCTGATCGGCGAGTTCCTGAGCGC
CCATGGCTACCAGGTGGATGTGGCCGAGAATGTCGCCGAAATGCGCAAGCGCATCACACAACGGCGTCCGGACCTCATCG
TACTCGACGTGATGATGCCGGGAGAAGACGGGCTGAGTGCGGCGCGTTCGCTGGCCAGCGAACGCGGCTCGCCTGCGGTG
ATCATGCTGAGCGCGCTGGGCAATGATACAGACCGCATCATCGGGCTGGAGGTTGGCGCCGACGATTACCTGGCCAAACC
CTGCAACCCGCGCGAGCTGCTGGCGCGGGTGCGCGCCCTGCTGCGCCGCAGCCAGGTCACCAGCGACCAGGCCGAGCCGC
GCGGCAATGTCTACGAGTTCGCCGGTTGGCGGCTGGACGTGGTGCGGCGCGACCTGCGCGACCCCACCGGTATCTTCATC
AACCTCTCCGACGGCGAATTCGCCCTGCTGCGCACCTTCGTGGAGCATCCGCAACGCGTGCTGAGCCGCGACCAACTGCT
CGACTACGCGCGCGGCCGCGATACCGACGTCTATGACCGCGCCATCGACAGCCAGATCAGCCGGCTGCGCCGCAAGATCA
ACGAACGCGTGCACACCGAGCTGATTCGCACCGTGCGCAACGAGGGCTACATGCTGCTGCCGAGCGTCGCGCGTCTGTGA

Upstream 100 bases:

>100_bases
GATCATTATGATGCGTGCTCCCGTCCTGCACCTTGCGAGCACCATGTTTCCGGTAGCCACCCCGCGCAGCCCGACCGTTG
CGCCTCCGACGATGACCTCC

Downstream 100 bases:

>100_bases
GTGAACCGGCACGCCGCGGGCTGTCGATCTTTGCCCGCACCTTCGTCCTGCTGGCGGTGGCCCTGGTCACCGCACAGGCG
GTCGGCATCGCCCTGCTGGT

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDMQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDVAENVAEMRKRITQRRPDLIVLDVMMPGEDGLSAARSLASERGSPAV
IMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQVTSDQAEPRGNVYEFAGWRLDVVRRDLRDPTGIFI
NLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTELIRTVRNEGYMLLPSVARL

Sequences:

>Translated_239_residues
MDMQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDVAENVAEMRKRITQRRPDLIVLDVMMPGEDGLSAARSLASERGSPAV
IMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQVTSDQAEPRGNVYEFAGWRLDVVRRDLRDPTGIFI
NLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTELIRTVRNEGYMLLPSVARL
>Mature_239_residues
MDMQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDVAENVAEMRKRITQRRPDLIVLDVMMPGEDGLSAARSLASERGSPAV
IMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRALLRRSQVTSDQAEPRGNVYEFAGWRLDVVRRDLRDPTGIFI
NLSDGEFALLRTFVEHPQRVLSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTELIRTVRNEGYMLLPSVARL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=44.6351931330472, Blast_Score=183, Evalue=7e-48,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=38.0952380952381, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.6812227074236, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=35.7142857142857, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=37.1794871794872, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=38.4615384615385, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=34.0336134453782, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.1880341880342, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.7510917030568, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786911, Length=208, Percent_Identity=31.7307692307692, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=32.6086956521739, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=31.0606060606061, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27140; Mature: 27140

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDVAENVAEMRKRITQRRPDLIVLDVMMP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEC
GEDGLSAARSLASERGSPAVIMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRAL
CCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHH
LRRSQVTSDQAEPRGNVYEFAGWRLDVVRRDLRDPTGIFINLSDGEFALLRTFVEHPQRV
HHHHHCCCCCCCCCCCEEHHCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTELIRTVRNEGYMLLPSVARL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCC
>Mature Secondary Structure
MDMQQPCVLVVDDDPDLRKLIGEFLSAHGYQVDVAENVAEMRKRITQRRPDLIVLDVMMP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEC
GEDGLSAARSLASERGSPAVIMLSALGNDTDRIIGLEVGADDYLAKPCNPRELLARVRAL
CCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHH
LRRSQVTSDQAEPRGNVYEFAGWRLDVVRRDLRDPTGIFINLSDGEFALLRTFVEHPQRV
HHHHHCCCCCCCCCCCEEHHCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSRDQLLDYARGRDTDVYDRAIDSQISRLRRKINERVHTELIRTVRNEGYMLLPSVARL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]