Click here to switch to the map view.

The map label for this gene is nodT [H]

Identifier: 66766774

GI number: 66766774

Start: 511621

End: 513093

Strand: Reverse

Name: nodT [H]

Synonym: XC_0432

Alternate gene names: 66766774

Gene position: 513093-511621 (Counterclockwise)

Preceding gene: 66766780

Following gene: 66766771

Centisome position: 9.97

GC content: 72.78

Gene sequence:

>1473_bases
ATGCCCTCTTTGCGCACCCTCACCGTGCTGCTCACCGCCAGCCTTGCCAGCTGCGCGGTCGGCCCCGAGTACGCTCGCCC
CGACGCCCCACTGCCGGACCGTTACCTGGCCCAGGACGCCGCCGAGCAGCGCAGTGCCGCTGCCCCGGTCGACCTGTCGC
GCTGGTGGGCCGGCTTTGGCGACCCGGCCCTGGACCGGTATGTCACAGCGGCGCTGGCGCAGAACCTGGACCTGGCCCAG
GCCGCCGCGCGCGTGACCCAGGCGCGCGCAGGGCTGGGCGCGGCCAACGCCGCCCTGCTGCCCTCCGGCAGCATCAATGG
CCAGGCCACCCGCACCTACCAATCGCTGGAAACCCCGCTGGGGCAGGTGCTGCGCAACACCCCGGACTTCGACCGCTATG
CCAGCGTTTACGACGCCACTGCCAACGCCAGCTGGGAGATCGATGTGTTCGGCGGGCTGCGCCGTGGCCGCCAGGCGGCA
CTGGCCGATTACCAGGCCAGCGCTGCCGGTGCGGCCGCCACGCGGCTGGCGGTGGCGGCGCAGACCGCCGACACCTACAT
CAGCATCCGTGGCCTGCAGGCACGGCTGGCGGTGGCCCAGCGCCAGGTCGCCACCCAACAGCAGCTGCTCGCCATGGTGA
CGCTGCTGCAGGGCAAGGGGCTGGCGGCCGACCTGCAGGTGCATCAGGCGCAGGGCGCGCTGACCCAGGCCCAGGCCGGC
GTGCCCGCGCTGGAGACCGCGCTGACCGCAGCGATGAACGCCCTGGACGTGATGCTGGGCGCCACGCCCGGCACCCACCG
GGCCGAGCTGGTGGCCAGCACGCCGATCCCGACCGCCCCGCAGGTGACCGGCGCCGCCTCGCCGGGGGACCTGTTGCGGC
GGCGGCCGGACCTGATCGTGGCCGAGCGCCGGCTGGCCGTGGCCAACGCGCGCATCGGCGTGGCCATGGCCGAGTACTAC
CCCAAATTCTCGCTGAGTGGATTGATCGGCAGTGCCACCGCCATCTCCGGCGCCAACCTGTTCACCGGCGACGCCGCGCA
GTCGGCCGGCGTGCTCGGGCTGCGTTGGCGGCTGTTCGATTTCGGCCGCATCAACGCGCAGATTGCACAGGCCAAGGGCC
AGGAAGCCGAACAGCTGGCCGCCTACCGGCTCGCCGTGCTGCGCGCCACCGAAGATGTGGAAAACGCGCTCACCGCGCTG
GTCAAACGCGAGCAGCAGGCCACCGTGCTGGCACAAGGCGTGGACGCGCTGGGCAAGGCACGCGGCGCCTCCGCCGCAGC
CTACGAGAAGGGCGTGGTCAGCCTGATCGAAGTCCTCAACGCCGACGACGCCTTGCTGCGCACCTCCGATGCGCAACTGC
AGGCGCAGACCGAGGCGGCCCGCAGCGCGGTAGCCGCGTTCAAGGCGCTGGGCGGCGGCTGGGAGAGCACGCCCGCCACC
GCAGTGGCGGTGCAGGAACCCGCGCAGCGCTGA

Upstream 100 bases:

>100_bases
CTTTGTTCATGCGCACAGCTTAACGCTCCAACGCGGGACATACAAAAGTGACCAATCCGTATTATAGTCACTGCACTTCC
ACTGCCAGACCGGCCCTGCC

Downstream 100 bases:

>100_bases
GACTGCGCGTACGGTCACGGGCCGTGCAGGGCGATAGCGCTGCCGGTGCCTGTGCTGTGGTTGCGTGCAGGGTGCAGGGT
GCAGGGTGGTAGCGGAGCAC

Product: outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPSLRTLTVLLTASLASCAVGPEYARPDAPLPDRYLAQDAAEQRSAAAPVDLSRWWAGFGDPALDRYVTAALAQNLDLAQ
AAARVTQARAGLGAANAALLPSGSINGQATRTYQSLETPLGQVLRNTPDFDRYASVYDATANASWEIDVFGGLRRGRQAA
LADYQASAAGAAATRLAVAAQTADTYISIRGLQARLAVAQRQVATQQQLLAMVTLLQGKGLAADLQVHQAQGALTQAQAG
VPALETALTAAMNALDVMLGATPGTHRAELVASTPIPTAPQVTGAASPGDLLRRRPDLIVAERRLAVANARIGVAMAEYY
PKFSLSGLIGSATAISGANLFTGDAAQSAGVLGLRWRLFDFGRINAQIAQAKGQEAEQLAAYRLAVLRATEDVENALTAL
VKREQQATVLAQGVDALGKARGASAAAYEKGVVSLIEVLNADDALLRTSDAQLQAQTEAARSAVAAFKALGGGWESTPAT
AVAVQEPAQR

Sequences:

>Translated_490_residues
MPSLRTLTVLLTASLASCAVGPEYARPDAPLPDRYLAQDAAEQRSAAAPVDLSRWWAGFGDPALDRYVTAALAQNLDLAQ
AAARVTQARAGLGAANAALLPSGSINGQATRTYQSLETPLGQVLRNTPDFDRYASVYDATANASWEIDVFGGLRRGRQAA
LADYQASAAGAAATRLAVAAQTADTYISIRGLQARLAVAQRQVATQQQLLAMVTLLQGKGLAADLQVHQAQGALTQAQAG
VPALETALTAAMNALDVMLGATPGTHRAELVASTPIPTAPQVTGAASPGDLLRRRPDLIVAERRLAVANARIGVAMAEYY
PKFSLSGLIGSATAISGANLFTGDAAQSAGVLGLRWRLFDFGRINAQIAQAKGQEAEQLAAYRLAVLRATEDVENALTAL
VKREQQATVLAQGVDALGKARGASAAAYEKGVVSLIEVLNADDALLRTSDAQLQAQTEAARSAVAAFKALGGGWESTPAT
AVAVQEPAQR
>Mature_489_residues
PSLRTLTVLLTASLASCAVGPEYARPDAPLPDRYLAQDAAEQRSAAAPVDLSRWWAGFGDPALDRYVTAALAQNLDLAQA
AARVTQARAGLGAANAALLPSGSINGQATRTYQSLETPLGQVLRNTPDFDRYASVYDATANASWEIDVFGGLRRGRQAAL
ADYQASAAGAAATRLAVAAQTADTYISIRGLQARLAVAQRQVATQQQLLAMVTLLQGKGLAADLQVHQAQGALTQAQAGV
PALETALTAAMNALDVMLGATPGTHRAELVASTPIPTAPQVTGAASPGDLLRRRPDLIVAERRLAVANARIGVAMAEYYP
KFSLSGLIGSATAISGANLFTGDAAQSAGVLGLRWRLFDFGRINAQIAQAKGQEAEQLAAYRLAVLRATEDVENALTALV
KREQQATVLAQGVDALGKARGASAAAYEKGVVSLIEVLNADDALLRTSDAQLQAQTEAARSAVAAFKALGGGWESTPATA
VAVQEPAQR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=474, Percent_Identity=25.5274261603376, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI2367348, Length=481, Percent_Identity=24.7401247401247, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50855; Mature: 50724

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLRTLTVLLTASLASCAVGPEYARPDAPLPDRYLAQDAAEQRSAAAPVDLSRWWAGFG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCC
DPALDRYVTAALAQNLDLAQAAARVTQARAGLGAANAALLPSGSINGQATRTYQSLETPL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
GQVLRNTPDFDRYASVYDATANASWEIDVFGGLRRGRQAALADYQASAAGAAATRLAVAA
HHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
QTADTYISIRGLQARLAVAQRQVATQQQLLAMVTLLQGKGLAADLQVHQAQGALTQAQAG
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHCC
VPALETALTAAMNALDVMLGATPGTHRAELVASTPIPTAPQVTGAASPGDLLRRRPDLIV
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEE
AERRLAVANARIGVAMAEYYPKFSLSGLIGSATAISGANLFTGDAAQSAGVLGLRWRLFD
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHCCCCCEECCCCHHCCCEEEEEEEEEE
FGRINAQIAQAKGQEAEQLAAYRLAVLRATEDVENALTALVKREQQATVLAQGVDALGKA
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGASAAAYEKGVVSLIEVLNADDALLRTSDAQLQAQTEAARSAVAAFKALGGGWESTPAT
CCCCHHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
AVAVQEPAQR
EEEECCCCCC
>Mature Secondary Structure 
PSLRTLTVLLTASLASCAVGPEYARPDAPLPDRYLAQDAAEQRSAAAPVDLSRWWAGFG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCC
DPALDRYVTAALAQNLDLAQAAARVTQARAGLGAANAALLPSGSINGQATRTYQSLETPL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
GQVLRNTPDFDRYASVYDATANASWEIDVFGGLRRGRQAALADYQASAAGAAATRLAVAA
HHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
QTADTYISIRGLQARLAVAQRQVATQQQLLAMVTLLQGKGLAADLQVHQAQGALTQAQAG
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHCC
VPALETALTAAMNALDVMLGATPGTHRAELVASTPIPTAPQVTGAASPGDLLRRRPDLIV
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEE
AERRLAVANARIGVAMAEYYPKFSLSGLIGSATAISGANLFTGDAAQSAGVLGLRWRLFD
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHCCCCCEECCCCHHCCCEEEEEEEEEE
FGRINAQIAQAKGQEAEQLAAYRLAVLRATEDVENALTALVKREQQATVLAQGVDALGKA
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGASAAAYEKGVVSLIEVLNADDALLRTSDAQLQAQTEAARSAVAAFKALGGGWESTPAT
CCCCHHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
AVAVQEPAQR
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2303029; 2338917 [H]