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The map label for this gene is fabZ

Identifier: 66044602

GI number: 66044602

Start: 1534928

End: 1535368

Strand: Direct

Name: fabZ

Synonym: Psyr_1354

Alternate gene names: 66044602

Gene position: 1534928-1535368 (Clockwise)

Preceding gene: 66044601

Following gene: 66044603

Centisome position: 25.19

GC content: 53.29

Gene sequence:

>441_bases
ATGATGGACATCAAAGAAATTCGCGAATACCTGCCTCATCGTTACCCGTTCCTGCTGGTGGATCGCGTGACCGAGCTGGA
TATCGAGAACAAGAACATTCGCGCCTACAAGAATGTCAGCGTCAATGAGCCTTTTTTCAACGGTCACTTCCCTGAGCATC
CCATCATGCCGGGCGTGCTGATCATCGAAGCGATGGCACAGGCTGCCGGTATCCTCGCGTTCAAGATGCTCGATTCCAAG
CCGTCGGACGGTACGCTCTATTATTTCGTCGGTTCGGACAAACTGCGTTTCCGTCAGCCGGTTCTGCCGGGCGACCAACT
GGTTCTCGAGGCGAAATTCCTGAGCAGCAAGCGTCAGATCTGGAAGTTCGAATGCAAGGCTACCGTTGATGGCAAGGCAG
TCTGCTCTGCCGAAATCATTTGTGCGGAACGCAAACTATGA

Upstream 100 bases:

>100_bases
AATATCAAGCGTGCTCAGTCGATAAACTGCCTCCTTGATGTAGAGGGGTGCTGCGCAGTCGCGACGCACTCCTAATCTTT
ACTACAGGCTTCCCCTCGAA

Downstream 100 bases:

>100_bases
GTTTGATTGACCCTCGCGCAATCATCGATCCGACGGCCGTTCTGGCCGACAATGTTGAGGTCGGCCCCTGGTCGATCATC
GGACCCGGTGTGGAAATTGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVLIIEAMAQAAGILAFKMLDSK
PSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQIWKFECKATVDGKAVCSAEIICAERKL

Sequences:

>Translated_146_residues
MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVLIIEAMAQAAGILAFKMLDSK
PSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQIWKFECKATVDGKAVCSAEIICAERKL
>Mature_146_residues
MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVLIIEAMAQAAGILAFKMLDSK
PSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQIWKFECKATVDGKAVCSAEIICAERKL

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=144, Percent_Identity=56.9444444444444, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PSE14 (Q48F70)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_275967.1
- ProteinModelPortal:   Q48F70
- SMR:   Q48F70
- STRING:   Q48F70
- GeneID:   3557645
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_3829
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q48F70
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16722; Mature: 16722

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: ACT_SITE 49-49

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVL
CCCHHHHHHHCCCCCCEEEEECHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQAAGILAFKMLDSKPSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQI
HHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEHHHHCCCCCE
WKFECKATVDGKAVCSAEIICAERKL
EEEEEEEEECCCEEEEEEEEEECCCC
>Mature Secondary Structure
MMDIKEIREYLPHRYPFLLVDRVTELDIENKNIRAYKNVSVNEPFFNGHFPEHPIMPGVL
CCCHHHHHHHCCCCCCEEEEECHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQAAGILAFKMLDSKPSDGTLYYFVGSDKLRFRQPVLPGDQLVLEAKFLSSKRQI
HHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEHHHHCCCCCE
WKFECKATVDGKAVCSAEIICAERKL
EEEEEEEEECCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA