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The map label for this gene is can [H]

Identifier: 66044114

GI number: 66044114

Start: 978220

End: 978858

Strand: Direct

Name: can [H]

Synonym: Psyr_0859

Alternate gene names: 66044114

Gene position: 978220-978858 (Clockwise)

Preceding gene: 66044112

Following gene: 66044118

Centisome position: 16.05

GC content: 58.06

Gene sequence:

>639_bases
ATGAACGAGCTACAAGACCTGATTGATAACAATGCACGCTGGGCCGATGCGATAAAGCAGGAAGATCCTGAGTTCTTTGC
CAAACTGGCCCGCCAGCAAACCCCTGAGTTCCTGTGGATCGGTTGCTCCGATGCACGCGTTCCGGCCAACGAAATCGTCG
GCATGCTGCCGGGTGATCTGTTCGTGCACCGCAACGTGGCCAACGTCGTGCTGCATACCGACCTGAATTGCCTGTCAGTG
ATTCAGTACGCAGTGGACGTATTGAAGGTCAAACACATTCTGGTCACAGGCCACTACGGTTGCGGTGGTGTGCGGGCGTC
CATGCAGGACCGCCAGTTCGGCCTGATCGACGGCTGGTTGCGCACGATTCGTGACCTGTATTACGAAAACCGCGAGTTGC
TGGCCAAGCTGCCGACCGAGGAAGAGCGCGTCGACCGCCTGTGTGAGTTGAACGTGATTCAGCAAGTGGCCAACGTCGGT
CACACCAGCATTGTGCAGAACGCCTGGCACCGTGGGCAGAGCCTGTCCGTGCATGGCTGCATCTATGGCATCAAGGATGG
CCGCTGGAAAAGCCTCGACGTGACCATCAGTGGTTTCGAGCAATTGCCCCCGCAGTACCGTCTGCGTCCGCAGGACTGA

Upstream 100 bases:

>100_bases
GTGGACCGGCCATGACTTTGAAGATTCCTTTTTTGTTGACCGTGACTTGAAGGATCTGACACCAGTCCAAGGCTGGGCAT
CATTATCGAGGCGTCAAAGC

Downstream 100 bases:

>100_bases
CAGCTGCTTATCGTCAGCCAGCCTGTGGCGCAGGCTGGCTGGCGAGTTTCAACCCATCACAGCACGAAACGCTGCACCAT
CAGGTTCAGATCAGTCGCCA

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNELQDLIDNNARWADAIKQEDPEFFAKLARQQTPEFLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRTIRDLYYENRELLAKLPTEEERVDRLCELNVIQQVANVG
HTSIVQNAWHRGQSLSVHGCIYGIKDGRWKSLDVTISGFEQLPPQYRLRPQD

Sequences:

>Translated_212_residues
MNELQDLIDNNARWADAIKQEDPEFFAKLARQQTPEFLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRTIRDLYYENRELLAKLPTEEERVDRLCELNVIQQVANVG
HTSIVQNAWHRGQSLSVHGCIYGIKDGRWKSLDVTISGFEQLPPQYRLRPQD
>Mature_212_residues
MNELQDLIDNNARWADAIKQEDPEFFAKLARQQTPEFLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSV
IQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWLRTIRDLYYENRELLAKLPTEEERVDRLCELNVIQQVANVG
HTSIVQNAWHRGQSLSVHGCIYGIKDGRWKSLDVTISGFEQLPPQYRLRPQD

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=207, Percent_Identity=56.5217391304348, Blast_Score=261, Evalue=2e-71,
Organism=Escherichia coli, GI1786534, Length=212, Percent_Identity=28.7735849056604, Blast_Score=80, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=210, Percent_Identity=31.4285714285714, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24164; Mature: 24164

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELQDLIDNNARWADAIKQEDPEFFAKLARQQTPEFLWIGCSDARVPANEIVGMLPGDL
CCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCHH
FVHRNVANVVLHTDLNCLSVIQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWL
EEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHH
RTIRDLYYENRELLAKLPTEEERVDRLCELNVIQQVANVGHTSIVQNAWHRGQSLSVHGC
HHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEE
IYGIKDGRWKSLDVTISGFEQLPPQYRLRPQD
EEECCCCCEEEEEEEECCHHHCCCCCCCCCCC
>Mature Secondary Structure
MNELQDLIDNNARWADAIKQEDPEFFAKLARQQTPEFLWIGCSDARVPANEIVGMLPGDL
CCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCHH
FVHRNVANVVLHTDLNCLSVIQYAVDVLKVKHILVTGHYGCGGVRASMQDRQFGLIDGWL
EEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHH
RTIRDLYYENRELLAKLPTEEERVDRLCELNVIQQVANVGHTSIVQNAWHRGQSLSVHGC
HHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEE
IYGIKDGRWKSLDVTISGFEQLPPQYRLRPQD
EEECCCCCEEEEEEEECCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]