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The map label for this gene is ttdR [H]

Identifier: 66043926

GI number: 66043926

Start: 747153

End: 748076

Strand: Direct

Name: ttdR [H]

Synonym: Psyr_0659

Alternate gene names: 66043926

Gene position: 747153-748076 (Clockwise)

Preceding gene: 66043924

Following gene: 66043927

Centisome position: 12.26

GC content: 62.88

Gene sequence:

>924_bases
ATGCTGCGTTTTGATGACTTGCAGTTGTTCGTACGTGCGGCGGATCTGGGCAGCCTTTCTGCCGCAGCGCGGGTCATGGA
CATGTCTGCGGCGGTTGCCAGCGCGGCGCTCAAGCGTATTGAACGGCAGTTGGGGACGCGCTTGCTGGCCCGCTCGACGC
GCAGCCTGCGCCTGACCGCCGAAGGTGAGGGGTTTCTGGAATACGCCCGCGCTGCACTGGGCAGCCTCGAGGAGGGGCGG
CGCTTGCTGGCCAGCAGCCAGGACCGTTGCGAGGGCGTGCTGCAACTCTCGGCGCCGTCGGACCTGGGGCGCAACGTGCT
GTTGCCGTGGCTCGACGAATTTCAACAGCAGCATCCGCAACTGACCGTGCGTCTGCTGCTGGGTGATCGTATTGCCGATC
TGTTCCGCCAGCCTGTCGACGTGGCGCTGCGCTACGGCGAGCCGGAAGATTCCAGCCTGGTCGCACTGCCAGTGTTGCCT
GACAACCGCCGGGTATTGTGTGCGGCGCCGAGTTACCTGCAGCGTCATGGCGAGCCGCATCAGGTCGAGCAACTGGCGCA
GCATAACTGCTTGCTGTTCATGCTCGGCGATCGCGTTCATGACCGTTGGACGCTGAACGACGGCAAGCGCGAAATCAGTC
TGACGGTCAGCGGCAACCGGTTCAGCGACGATGCCGACGTCGTGCGCCGCTGGGCGGTTGCAGGTGAAGGTGTGGCGTAC
AAATCCTGGCTGGACGTGGCCGCAGATGTGCGGGCCGGGCACCTGAAAGTCTTGATGCCTGACCTGGTCGGGGAGCGGGC
GCCGTTGAACCTGTTGTGTGCGCATCGGGCGCAACTCAGTAAGCCTGTCATTCTGTTACTGGAAATGCTCAGGTCACGGT
GTAAGCAACATGCTGTAGGTCTGTCGTCCGCAAACTTGTTTTAA

Upstream 100 bases:

>100_bases
AGAAAAAAGTGATGAAGAGATCATTGGCTATTTCCAGTAAAGATAAAACCCGCTAAAACGGCAGGCTCTTTCAATTTTAT
TTTGATAATACGAGGGCATG

Downstream 100 bases:

>100_bases
TCGCCGCGTCCCGGTAGGAAATAGCCTTCGGAAGTGTCGGAAAATATAATTTTCAAAGGCATTTCAATAACGCGAAGTTT
CACTGCCGGGACAAAGTTGA

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLRFDDLQLFVRAADLGSLSAAARVMDMSAAVASAALKRIERQLGTRLLARSTRSLRLTAEGEGFLEYARAALGSLEEGR
RLLASSQDRCEGVLQLSAPSDLGRNVLLPWLDEFQQQHPQLTVRLLLGDRIADLFRQPVDVALRYGEPEDSSLVALPVLP
DNRRVLCAAPSYLQRHGEPHQVEQLAQHNCLLFMLGDRVHDRWTLNDGKREISLTVSGNRFSDDADVVRRWAVAGEGVAY
KSWLDVAADVRAGHLKVLMPDLVGERAPLNLLCAHRAQLSKPVILLLEMLRSRCKQHAVGLSSANLF

Sequences:

>Translated_307_residues
MLRFDDLQLFVRAADLGSLSAAARVMDMSAAVASAALKRIERQLGTRLLARSTRSLRLTAEGEGFLEYARAALGSLEEGR
RLLASSQDRCEGVLQLSAPSDLGRNVLLPWLDEFQQQHPQLTVRLLLGDRIADLFRQPVDVALRYGEPEDSSLVALPVLP
DNRRVLCAAPSYLQRHGEPHQVEQLAQHNCLLFMLGDRVHDRWTLNDGKREISLTVSGNRFSDDADVVRRWAVAGEGVAY
KSWLDVAADVRAGHLKVLMPDLVGERAPLNLLCAHRAQLSKPVILLLEMLRSRCKQHAVGLSSANLF
>Mature_307_residues
MLRFDDLQLFVRAADLGSLSAAARVMDMSAAVASAALKRIERQLGTRLLARSTRSLRLTAEGEGFLEYARAALGSLEEGR
RLLASSQDRCEGVLQLSAPSDLGRNVLLPWLDEFQQQHPQLTVRLLLGDRIADLFRQPVDVALRYGEPEDSSLVALPVLP
DNRRVLCAAPSYLQRHGEPHQVEQLAQHNCLLFMLGDRVHDRWTLNDGKREISLTVSGNRFSDDADVVRRWAVAGEGVAY
KSWLDVAADVRAGHLKVLMPDLVGERAPLNLLCAHRAQLSKPVILLLEMLRSRCKQHAVGLSSANLF

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=30.0341296928328, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=28.9036544850498, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786401, Length=262, Percent_Identity=29.7709923664122, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=28.6689419795222, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=27.6450511945392, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=28.5234899328859, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=23.3676975945017, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786448, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=27.8810408921933, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=235, Percent_Identity=24.6808510638298, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=209, Percent_Identity=24.8803827751196, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34053; Mature: 34053

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFDDLQLFVRAADLGSLSAAARVMDMSAAVASAALKRIERQLGTRLLARSTRSLRLTA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EGEGFLEYARAALGSLEEGRRLLASSQDRCEGVLQLSAPSDLGRNVLLPWLDEFQQQHPQ
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
LTVRLLLGDRIADLFRQPVDVALRYGEPEDSSLVALPVLPDNRRVLCAAPSYLQRHGEPH
EEEHHHHHHHHHHHHHCCHHHEEECCCCCCCCEEEEEECCCCCEEEEECCHHHHHCCCHH
QVEQLAQHNCLLFMLGDRVHDRWTLNDGKREISLTVSGNRFSDDADVVRRWAVAGEGVAY
HHHHHHHCCEEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCH
KSWLDVAADVRAGHLKVLMPDLVGERAPLNLLCAHRAQLSKPVILLLEMLRSRCKQHAVG
HHHHHHHHHCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
LSSANLF
CCCCCCC
>Mature Secondary Structure
MLRFDDLQLFVRAADLGSLSAAARVMDMSAAVASAALKRIERQLGTRLLARSTRSLRLTA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EGEGFLEYARAALGSLEEGRRLLASSQDRCEGVLQLSAPSDLGRNVLLPWLDEFQQQHPQ
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
LTVRLLLGDRIADLFRQPVDVALRYGEPEDSSLVALPVLPDNRRVLCAAPSYLQRHGEPH
EEEHHHHHHHHHHHHHCCHHHEEECCCCCCCCEEEEEECCCCCEEEEECCHHHHHCCCHH
QVEQLAQHNCLLFMLGDRVHDRWTLNDGKREISLTVSGNRFSDDADVVRRWAVAGEGVAY
HHHHHHHCCEEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCH
KSWLDVAADVRAGHLKVLMPDLVGERAPLNLLCAHRAQLSKPVILLLEMLRSRCKQHAVG
HHHHHHHHHCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
LSSANLF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]