Click here to switch to the map view.

The map label for this gene is yvkA [H]

Identifier: 62390249

GI number: 62390249

Start: 1430658

End: 1432109

Strand: Reverse

Name: yvkA [H]

Synonym: cg1545

Alternate gene names: 62390249

Gene position: 1432109-1430658 (Counterclockwise)

Preceding gene: 62390250

Following gene: 62390248

Centisome position: 43.63

GC content: 56.2

Gene sequence:

>1452_bases
ATGTCACTTCCTGTTCAGCCGAGTAAAACCTCGGCCGCCACAGTCATACCATTGATGATCGCCCTGCTGGTCGCGGTATT
CGCCTTCCAGCTCAACGCCTCCATGCTGGCGCCGGCACTGGCCACCATGGAAACTGAACTTAATGCAACAGCTGCCCAAA
TCGGCATGACGCAGACTGCTTTCTTCACCGCGGCGGCGCTGTTTTCCCTGTTCCTGCCACGTTGGGGCGATCTGATTGGT
CGCCGCAAAGTGCTGGTCGGCATGATGATTGTCACCGGTATTGGATGTGTTGTCGCTGCCTTTGCTCCGAATGTGACCAT
CCTCTTCCTGGGCCGCCTGATTCAAGGTGTTGCTGGCCCAACCGTGCCACTGTGTCTGATCATTCTGCGCCAGCAGGTAA
CCAATGAAAAGCAATATGCGCTACTTCTCGGAATTGTTACCTCTGTCAACGGTGGTATCGGCGGCGTGGACGCGCTTGCT
GGTGGCTGGTTGGCTGAAACACTTGGTTTCCGTTCCATCTTCTGGGTCATGGCTGCTTTCTGCGCTGTCGCTGCCCTCGC
ACTGCCTTTCAGCGTGAAGGAATCCACCGCTGAAGAAACCCCGAAGATGGACTGGCTTGGTGTGCTGCCACTGGCGGTGT
CCATTGGATCTTTGCTCATGGCTTTCAACGAGGCCGGCAAACTCGGTGCCGCGAACTGGATTCTGGTGGTTGTGCTGTTC
ATCATCGGTATCGCCGGAGTCATCTTCTTCTACAACATTGAAAAGCGCGTTAAGCACCCGCTGGTCAGTGTTGAATACCT
CGGTCAACGACGCACCTGGGCATTGCTGCTGAGCACCCTTCTCACAATGACCGGTGTATTCGCCGTAATGAATGGTCTGC
TGCCCAACCTTGCGCAGGATGCTGCCAACGGTGCCGGCATGTCAGCGAGCGTGGTGTCCTGGTGGACACTTACCCCATAT
GCGCTGGCTGGCTTGGTATTCGGTCCAATCGCCGGAATTCTCGCCGGAAAATTTGGATACAAGATCGTCCTGCAAATTGG
TATCGCTGCCACCATCATCGGCGTTGCCGGAGCCACCTTCTTAGTCGGAAGCACCTCGCATCTCGCGTACCTCGGCATCT
CCATCTTCGTGGGTATTACCTATGCAGGTATTGCCAACATCATGCTCAACGGCCTGGGCATCGTGCTCTCCCCTGCTAAC
AACCAAGGCTATCTGCCTGGCATGAACGCAGGTGCCTTCAACCTAGGTGCAGGTATTTCCTTCGCCATCCTCTTCGCAGT
TTCCACGGCATTCAGTGACAACGGCGGAGGATACGCCGCAGGCATGTGGGCTGGCGTGATCATCTTGGTCCTAGCCTTCC
TCTGCTCCCTGCTGATCCCACGCCCAGAATCAATCACCGATACAGTGGCAGCCAAAGTCCAGGCTGAAGAAGCCGCTCAA
GCCGCCAGCTAA

Upstream 100 bases:

>100_bases
CGCGTTGGCGCTTATGCCGCCACGAGGCCGGGCGCTCAAGCCTCCTACCCCACCCTGACCACTGACCTCCCCTCAACCAC
TCACTGAAAAGAGAACACTG

Downstream 100 bases:

>100_bases
ATCCACAAACTGAACTAAGGAGTTTTACCCTATGACCACCAAGATCATCCTCGACTGCGATCCAGGACACGACGACGCTG
TAGCCATGCTGCTCGCAGCC

Product: major facilitator superfamily permease

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIG
RRKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALA
GGWLAETLGFRSIFWVMAAFCAVAALALPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLF
IIGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPY
ALAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPAN
NQGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNGGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQ
AAS

Sequences:

>Translated_483_residues
MSLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIG
RRKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALA
GGWLAETLGFRSIFWVMAAFCAVAALALPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLF
IIGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPY
ALAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPAN
NQGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNGGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQ
AAS
>Mature_482_residues
SLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTAFFTAAALFSLFLPRWGDLIGR
RKVLVGMMIVTGIGCVVAAFAPNVTILFLGRLIQGVAGPTVPLCLIILRQQVTNEKQYALLLGIVTSVNGGIGGVDALAG
GWLAETLGFRSIFWVMAAFCAVAALALPFSVKESTAEETPKMDWLGVLPLAVSIGSLLMAFNEAGKLGAANWILVVVLFI
IGIAGVIFFYNIEKRVKHPLVSVEYLGQRRTWALLLSTLLTMTGVFAVMNGLLPNLAQDAANGAGMSASVVSWWTLTPYA
LAGLVFGPIAGILAGKFGYKIVLQIGIAATIIGVAGATFLVGSTSHLAYLGISIFVGITYAGIANIMLNGLGIVLSPANN
QGYLPGMNAGAFNLGAGISFAILFAVSTAFSDNGGGYAAGMWAGVIILVLAFLCSLLIPRPESITDTVAAKVQAEEAAQA
AS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50079; Mature: 49948

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SLPVQPSKTSAATVIPLMIALLVAVFAFQLNASMLAPALATMETELNATAAQIGMTQTA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHH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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]