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The map label for this gene is rbsK1 [H]

Identifier: 62390250

GI number: 62390250

Start: 1432123

End: 1433046

Strand: Reverse

Name: rbsK1 [H]

Synonym: cg1546

Alternate gene names: 62390250

Gene position: 1433046-1432123 (Counterclockwise)

Preceding gene: 62390251

Following gene: 62390249

Centisome position: 43.65

GC content: 57.03

Gene sequence:

>924_bases
ATGAGTAACTCAACCGGTACCGACATTGTCGTTGTCGGATCCATCAATGCCGATCTCACCGCAAAAGTTCAACGCCACCC
TGAACCTGGAGAAACCCTCCTGGGTAGCGGCGGCACAGTGAGTGCTGGTGGCAAAGGCGCCAACCAAGCTGTGGCGGCAG
CGCAATTAGGTGCCAAAGTCACCATGATCGGTGCGGTCGGAACCGATCAAATGGCTGGCGAGGCGCTGACACATTTGCGT
CAATCAGGAGCAGATATGTCCGCGATTGCCACTGTGGACGGTCCCACTGGTCTTGCCATCATCACTGTGTCTGACGATGG
GGAAAACACCATCATCGTTATCCCTGGCGCTAACGCTTCTGTCACCGCGGAATTTGTTGATAAACACTCCCAACTCATTG
AGAACGCCGGCATTGTGTTGCTTCAGGGTGAGATCCCTGCCGATGGTTTCGAGCGTGCCGTTGATCTTTCACAAGGACGT
GTGGTGATCAATCTGGCTCCAGTTGTGCCCGTGGGACATGATCAGCTGCGTCGTGCCGATCCATTGCTGGTCAACGAACA
CGAAGGCGCTCTGGTGCTGGACATGCTTGGAACTCCAGCGACCACGTCTGATCCCCAAAGTTTGGTCACTGAATTGCTGG
AGCAGGGTTTTACTTCCGTGGTGATGACACTTGGTGCCGAAGGTGCTCTGGTTGGCACGCCGGGCCAACTCACGGCAATT
CCTACCCCAAAGATCCAGGCAGTCGACACAACCGGAAGTGGAGACGCGTTTGCGGGGGCACTCGTCGCAAAGCTCTCTGA
AGGCGCTGGCCTTATTGAGGCGGCAACTTTTGCTGCGCGCGTTGGCGCTTATGCCGCCACGAGGCCGGGCGCTCAAGCCT
CCTACCCCACCCTGACCACTGACCTCCCCTCAACCACTCACTGA

Upstream 100 bases:

>100_bases
GGCACGGTACCTAGCGTGACGAAAACTACGATCCCCACTGCCCTTATTCATCGTGAATCAATCATCAACTCCACTTTAAG
GAAGAAGGATGGACTCCCCA

Downstream 100 bases:

>100_bases
AAAGAGAACACTGATGTCACTTCCTGTTCAGCCGAGTAAAACCTCGGCCGCCACAGTCATACCATTGATGATCGCCCTGC
TGGTCGCGGTATTCGCCTTC

Product: ribokinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSNSTGTDIVVVGSINADLTAKVQRHPEPGETLLGSGGTVSAGGKGANQAVAAAQLGAKVTMIGAVGTDQMAGEALTHLR
QSGADMSAIATVDGPTGLAIITVSDDGENTIIVIPGANASVTAEFVDKHSQLIENAGIVLLQGEIPADGFERAVDLSQGR
VVINLAPVVPVGHDQLRRADPLLVNEHEGALVLDMLGTPATTSDPQSLVTELLEQGFTSVVMTLGAEGALVGTPGQLTAI
PTPKIQAVDTTGSGDAFAGALVAKLSEGAGLIEAATFAARVGAYAATRPGAQASYPTLTTDLPSTTH

Sequences:

>Translated_307_residues
MSNSTGTDIVVVGSINADLTAKVQRHPEPGETLLGSGGTVSAGGKGANQAVAAAQLGAKVTMIGAVGTDQMAGEALTHLR
QSGADMSAIATVDGPTGLAIITVSDDGENTIIVIPGANASVTAEFVDKHSQLIENAGIVLLQGEIPADGFERAVDLSQGR
VVINLAPVVPVGHDQLRRADPLLVNEHEGALVLDMLGTPATTSDPQSLVTELLEQGFTSVVMTLGAEGALVGTPGQLTAI
PTPKIQAVDTTGSGDAFAGALVAKLSEGAGLIEAATFAARVGAYAATRPGAQASYPTLTTDLPSTTH
>Mature_306_residues
SNSTGTDIVVVGSINADLTAKVQRHPEPGETLLGSGGTVSAGGKGANQAVAAAQLGAKVTMIGAVGTDQMAGEALTHLRQ
SGADMSAIATVDGPTGLAIITVSDDGENTIIVIPGANASVTAEFVDKHSQLIENAGIVLLQGEIPADGFERAVDLSQGRV
VINLAPVVPVGHDQLRRADPLLVNEHEGALVLDMLGTPATTSDPQSLVTELLEQGFTSVVMTLGAEGALVGTPGQLTAIP
TPKIQAVDTTGSGDAFAGALVAKLSEGAGLIEAATFAARVGAYAATRPGAQASYPTLTTDLPSTTH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=308, Percent_Identity=35.3896103896104, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1790193, Length=293, Percent_Identity=35.4948805460751, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788484, Length=310, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081971, Length=272, Percent_Identity=25.7352941176471, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788491, Length=285, Percent_Identity=23.859649122807, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=304, Percent_Identity=36.5131578947368, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=30.030959752322, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322565, Length=261, Percent_Identity=27.5862068965517, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=34.1059602649007, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=29.2763157894737, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30770; Mature: 30639

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSTGTDIVVVGSINADLTAKVQRHPEPGETLLGSGGTVSAGGKGANQAVAAAQLGAKV
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEECCCCEECCCCCCCHHHHHHHHCCCEE
TMIGAVGTDQMAGEALTHLRQSGADMSAIATVDGPTGLAIITVSDDGENTIIVIPGANAS
EEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCE
VTAEFVDKHSQLIENAGIVLLQGEIPADGFERAVDLSQGRVVINLAPVVPVGHDQLRRAD
EEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCC
PLLVNEHEGALVLDMLGTPATTSDPQSLVTELLEQGFTSVVMTLGAEGALVGTPGQLTAI
CEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEEC
PTPKIQAVDTTGSGDAFAGALVAKLSEGAGLIEAATFAARVGAYAATRPGAQASYPTLTT
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCEEEC
DLPSTTH
CCCCCCC
>Mature Secondary Structure 
SNSTGTDIVVVGSINADLTAKVQRHPEPGETLLGSGGTVSAGGKGANQAVAAAQLGAKV
CCCCCCCEEEEECCCCCEEEEEECCCCCCCEEECCCCEECCCCCCCHHHHHHHHCCCEE
TMIGAVGTDQMAGEALTHLRQSGADMSAIATVDGPTGLAIITVSDDGENTIIVIPGANAS
EEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCE
VTAEFVDKHSQLIENAGIVLLQGEIPADGFERAVDLSQGRVVINLAPVVPVGHDQLRRAD
EEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCC
PLLVNEHEGALVLDMLGTPATTSDPQSLVTELLEQGFTSVVMTLGAEGALVGTPGQLTAI
CEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEEC
PTPKIQAVDTTGSGDAFAGALVAKLSEGAGLIEAATFAARVGAYAATRPGAQASYPTLTT
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCEEEC
DLPSTTH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]