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The map label for this gene is dapA [C]

Identifier: 62389353

GI number: 62389353

Start: 477044

End: 477994

Strand: Reverse

Name: dapA [C]

Synonym: cg0536

Alternate gene names: 62389353

Gene position: 477994-477044 (Counterclockwise)

Preceding gene: 62389354

Following gene: 62389352

Centisome position: 14.56

GC content: 55.84

Gene sequence:

>951_bases
ATGGCACGCTTTTCACCACAAGATCTCGCAGACCACCTCAAGGATGGACTGCTCTCTTTCCCGGCCACCGCTTTCCAAGA
TGACCTCGAAGTAGATGAAGCTGCTTATGTCGAGCACATTGAATGGCAGTCCAGCTACCCAGTCGCCGGCCTCTTCGCAG
CTGGCGGTACTGGCGAAGGATTCAGCCTTACCGTTGAGGAAAACCACCGTGTCACTCAACTTGCAGTTCAGGCGTCCAGC
CCGGAAGTTCCCGTGTTGGGGTCTGCTACTGGCTCAACTAAGTCTGCCATCGCAAACGCACAGGGCGCAGAGGCAGCAGG
CGCTGAAGGTGTCCTCCTGCTTCCTCCCTACCTCACCGAATGCGACGCAGAAGGCCTGTACAACCATGCAGCCGCAGTCT
GTGAATCCACTTCTCTTGGTGTCATCGTGTACAACCGTGCCAATGCCATCTACTCCCCAGAGGTTATCGCTCGACTCTCT
GAGCGCTACCCCAACTTCATTGGATTTAAAGATGGCACCGGAAACATCGAGCACCTAGCAAAGATCACCACGCTATGCGG
AGATCGCCTGTTCTACCTCGGTGGACTTCCCACCGCTGAGACCTTTGCACTACCACTGCTTCAGATGGGCATGAGCACCT
ACTCCTCTGCAATGTTCAACTTCATTCCAGATTTCGCACTGAGCTTCTACGCCGATGTTCGTGCGCAGGACAGCGCAGCA
GTAAAGCAGAAGCTGAGCGATTTTGTGCTCCCCTACTTGGATATCCGCGATCGCGCACAAGGCTACGGTGTCTCCATTGT
TAAGGGCGGACTCAAGGCTGTTGGCCGCAACGCTGGCGGCGTTCGCCCACCACTGCGTAACCTTTCCGAGCAAGATATCG
CGGACCTGTCGGATTTGCTTGCCACCTCTGGCGCAGGTTCCTACCGCCTTCCAGTTGAGGTGAAAGCATGA

Upstream 100 bases:

>100_bases
CTTTTAAGCATTTCAACATGCCAAACTAATCTTGGACAGGTATCACTGGCTCCTCTTAGACTCCAAAGTGTCTTAGAAAA
CACTCACCCAAGGAGCCCTC

Downstream 100 bases:

>100_bases
TCACCGCAACCGCACTGCATGGGTGTTCACTGATTGATGGCGAGTGGGTCGCTGGAAAAAATGGTGAGATTACAGGATTC
GATCCGCGCACCAATGCGAG

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEGFSLTVEENHRVTQLAVQASS
PEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTECDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLS
ERYPNFIGFKDGTGNIEHLAKITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAA
VKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLLATSGAGSYRLPVEVKA

Sequences:

>Translated_316_residues
MARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEGFSLTVEENHRVTQLAVQASS
PEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTECDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLS
ERYPNFIGFKDGTGNIEHLAKITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAA
VKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLLATSGAGSYRLPVEVKA
>Mature_315_residues
ARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEGFSLTVEENHRVTQLAVQASSP
EVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTECDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLSE
RYPNFIGFKDGTGNIEHLAKITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAAV
KQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLLATSGAGSYRLPVEVKA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=192, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082415, Length=304, Percent_Identity=25.9868421052632, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786463, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 33552; Mature: 33421

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEG
CCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCC
FSLTVEENHRVTQLAVQASSPEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTE
EEEEEECCCCEEEEEEECCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCEEECCCCHHH
CDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLSERYPNFIGFKDGTGNIEHLA
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHHH
KITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLL
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHH
ATSGAGSYRLPVEVKA
HHCCCCCEEECEEECC
>Mature Secondary Structure 
ARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEG
CCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCC
FSLTVEENHRVTQLAVQASSPEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTE
EEEEEECCCCEEEEEEECCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCEEECCCCHHH
CDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLSERYPNFIGFKDGTGNIEHLA
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHHH
KITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLL
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHH
ATSGAGSYRLPVEVKA
HHCCCCCEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA