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The map label for this gene is lolB [H]

Identifier: 59711373

GI number: 59711373

Start: 836284

End: 836910

Strand: Reverse

Name: lolB [H]

Synonym: VF_0766

Alternate gene names: 59711373

Gene position: 836910-836284 (Counterclockwise)

Preceding gene: 59711380

Following gene: 59711372

Centisome position: 28.88

GC content: 36.68

Gene sequence:

>627_bases
ATGAGATTATCAAGAATGTTTCCTCGCTTTGTACGTTCCCCTTTTACTATTCTCATATTCACGCTTTTTCTTAACGCCTG
TTCAACGACCCCTTTAACACCTCAACAATCGACAGATTGGGATAAACATCAAGCAAAACTCGAACAGATTACGCAATATA
AAGTAACAGGAAAAATCGGATATCAAGCACCAAACCAACGCCATAGTTTAAATTTCCAGTGGATTCAAAAACCAGAACAA
AGTCAACTATTGCTCACTTCATTTCTTGGCCAAACGGTAATGAAACTAACAATGACAGAGCAAATGACAACAATCGAGAC
TGGCGATGGGCAAAAATTTGAAGGTCGTGATCCTGGAAAATTAATGTATAGCTTAAGTGGCATCAGCATGCCTATAGGGT
ATTTACAAGATTGGATTAAAGGCTTACCGACCGCAGCAGATAATTTCCAACTCAATGAGCTTAATACTGTAGAACACTTA
TCAAAACAAATTGGTCAAACTAACTGGCATTTACGTTACAACAGCTATATTGAAAAAAGTAACCTACTTCTCCCTAATTC
AATGAAACTCACTCAACAAGATACCACCATTAAAATCATTGCTTCAAATTGGATAATTTCTCAATGA

Upstream 100 bases:

>100_bases
ATCAAGGCTTTTGTGTAAGAAATTAGTGATATTCAAATACTATTTGGCTCCAAATTCGCCATTAATTTGCTACAATTGTT
GCATTACTTCAGAATTAAAG

Downstream 100 bases:

>100_bases
TCACCAAAACAACTCGCTGGCCATCCCCAGCCAAATTAAACCTATTTCTTTATATCAATGGCCAACAAGAAAATGGCTAC
CATGAGCTTCAAACTTTATT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MRLSRMFPRFVRSPFTILIFTLFLNACSTTPLTPQQSTDWDKHQAKLEQITQYKVTGKIGYQAPNQRHSLNFQWIQKPEQ
SQLLLTSFLGQTVMKLTMTEQMTTIETGDGQKFEGRDPGKLMYSLSGISMPIGYLQDWIKGLPTAADNFQLNELNTVEHL
SKQIGQTNWHLRYNSYIEKSNLLLPNSMKLTQQDTTIKIIASNWIISQ

Sequences:

>Translated_208_residues
MRLSRMFPRFVRSPFTILIFTLFLNACSTTPLTPQQSTDWDKHQAKLEQITQYKVTGKIGYQAPNQRHSLNFQWIQKPEQ
SQLLLTSFLGQTVMKLTMTEQMTTIETGDGQKFEGRDPGKLMYSLSGISMPIGYLQDWIKGLPTAADNFQLNELNTVEHL
SKQIGQTNWHLRYNSYIEKSNLLLPNSMKLTQQDTTIKIIASNWIISQ
>Mature_208_residues
MRLSRMFPRFVRSPFTILIFTLFLNACSTTPLTPQQSTDWDKHQAKLEQITQYKVTGKIGYQAPNQRHSLNFQWIQKPEQ
SQLLLTSFLGQTVMKLTMTEQMTTIETGDGQKFEGRDPGKLMYSLSGISMPIGYLQDWIKGLPTAADNFQLNELNTVEHL
SKQIGQTNWHLRYNSYIEKSNLLLPNSMKLTQQDTTIKIIASNWIISQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=210, Percent_Identity=29.5238095238095, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 23963; Mature: 23963

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSRMFPRFVRSPFTILIFTLFLNACSTTPLTPQQSTDWDKHQAKLEQITQYKVTGKIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEC
YQAPNQRHSLNFQWIQKPEQSQLLLTSFLGQTVMKLTMTEQMTTIETGDGQKFEGRDPGK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHH
LMYSLSGISMPIGYLQDWIKGLPTAADNFQLNELNTVEHLSKQIGQTNWHLRYNSYIEKS
EEEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCCCC
NLLLPNSMKLTQQDTTIKIIASNWIISQ
CEECCCCCEECCCCCEEEEEECCCEECC
>Mature Secondary Structure
MRLSRMFPRFVRSPFTILIFTLFLNACSTTPLTPQQSTDWDKHQAKLEQITQYKVTGKIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEC
YQAPNQRHSLNFQWIQKPEQSQLLLTSFLGQTVMKLTMTEQMTTIETGDGQKFEGRDPGK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHH
LMYSLSGISMPIGYLQDWIKGLPTAADNFQLNELNTVEHLSKQIGQTNWHLRYNSYIEKS
EEEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCCCC
NLLLPNSMKLTQQDTTIKIIASNWIISQ
CEECCCCCEECCCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA