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The map label for this gene is nrdR [H]

Identifier: 54293710

GI number: 54293710

Start: 867861

End: 868328

Strand: Direct

Name: nrdR [H]

Synonym: lpl0763

Alternate gene names: 54293710

Gene position: 867861-868328 (Clockwise)

Preceding gene: 54293709

Following gene: 54293711

Centisome position: 25.94

GC content: 39.53

Gene sequence:

>468_bases
ATGTATTGTCCATTTTGTCATGCGGAAGAAACAAAGGTAGTGGATTCACGTCTGGTCGCGGATGGTGCTCAAGTTCGCAG
AAGGCGTGAATGTCTTGAATGTCATGAGCGCTTTACTACTTTTGAAACCGCTGAATTGATTATGCCATTGATTATAAAAC
GTGATGGAAGAAGAGAACCGTTTCATATTGATAATTTACGTTCTGGCATGTTGAGAGCCTTGGAGAAAAGACCTGTCAGC
GTTGATGATTTGGAAAAAGCTATTATTTCTATCACTGAGGAAATTCGAAGAAGAGGTGAACGCGAGATCGATTCCCAGAT
GGTTGGCGAGTTGGTAATGAAGGAATTATTCAGGCTTGATCATGTGGCCTATGTGCGTTTTGCATCAGTGTATAAACGCT
TTAAAGATGTGAGTGATTTTAGACAAACAATTGATCAAATGAAAAATGAAGATAAGGAAAAGTCTTAG

Upstream 100 bases:

>100_bases
TAGCTGATGTCCTTGATAATGTTCATGATGAAACTAATATTTCAAGAGTGAAAACCCAGGTGCTGCTACTCTGTCGTGAA
TTTCCGGTTTATGCCTAATC

Downstream 100 bases:

>100_bases
ATAAAAATGTGAAGGGCTCACTTTTCTTGTTGTTATTAGAATAATATGAGGTAATTGTGGAAAAACAATCAATTCGTGGT
AAAAGACGAGCTCGAAAATT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREPFHIDNLRSGMLRALEKRPVS
VDDLEKAIISITEEIRRRGEREIDSQMVGELVMKELFRLDHVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS

Sequences:

>Translated_155_residues
MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREPFHIDNLRSGMLRALEKRPVS
VDDLEKAIISITEEIRRRGEREIDSQMVGELVMKELFRLDHVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS
>Mature_155_residues
MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREPFHIDNLRSGMLRALEKRPVS
VDDLEKAIISITEEIRRRGEREIDSQMVGELVMKELFRLDHVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=59.0604026845638, Blast_Score=190, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18396; Mature: 18396

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FHIDNLRSGMLRALEKRPVSVDDLEKAIISITEEIRRRGEREIDSQMVGELVMKELFRLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FHIDNLRSGMLRALEKRPVSVDDLEKAIISITEEIRRRGEREIDSQMVGELVMKELFRLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA