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The map label for this gene is argF [H]

Identifier: 54293485

GI number: 54293485

Start: 580282

End: 581397

Strand: Direct

Name: argF [H]

Synonym: lpl0534

Alternate gene names: 54293485

Gene position: 580282-581397 (Clockwise)

Preceding gene: 54293484

Following gene: 54293487

Centisome position: 17.34

GC content: 40.05

Gene sequence:

>1116_bases
ATGTCTTTTTCCACCTCAACCAATTTGACTCCAATTGAAATGCAAGACGATGACCTTGAAAAAATTCAATCTCAGAATAA
CCCATCTGCAATTAATGAAGTAAAGACCAATACTTTTGTCATTAATTTACAACAAGCTATTTTTGGCCTGGAGACGGGTA
GTGAGGCCATTAATCTTGTTTCTCATAAGAATACAGGCTTTCCATTTCCTGCCGGTGAATACAAACCAAGACATTTTCTT
ACTGGCACAGAGTTAGCAAGGGAGGAAATTCAGTTTATTTTAAGCCAGGCTCGCTCTCTAAAACAAAACCCGGGGTTATA
TAATCAGGCACTTGCTAATAAAAGTTTGGTAATGATTTTTGAAAAACCTTCCTTTAGAACCCGTTTGAGTTTTGCTTTAG
CGATTCAGAGTATGGGGGGGCTCGTTGTTGAAAGCATCGCTAACTCAAGAAAGCAGGAGACTCCAGCTGATATGGCTAGA
GTTTTAAATGGCTATGCTGATTTTGTAATGGTCAGAACACATGAGGACAGATTTTTGCAAGAAATGGCCGAATATTCCAA
AATCCCTATTATTAATGGCCTCTCCGCATTGCATCACCCTTGTCAAACTCTTGCTGACTTGTTAAGCCTTGAAGAACAAT
TTGGTGCTTTGGAAGGATTAACCCTCACTTACATAGGGGATGGCAATAATATTTTGCATAGTTTGATGCTTTTGGCACCG
CAGTTAGGTGTCACTGTGCATTATTGTTGCCCAAAATCAAATCAGCCTAATGAGACTATTGTTAAGGAGGCCCAAAGCAA
GGCAGGGAAACAAATGATTTATTATTTTGATAAACCAGAGGAGGCCGTGAAGCAAGCGGATGCCGTTTATACTGATGTGT
GGACAAGTATGGGATTTGATAATCCTGAAGCGGGCAAGATTTTTAAAGGGTTCCAGGTTAATGAAACATTAATGTCTCAT
GCAAAACCCGATTCGGTGTTTATGCATTGTATGCCTATGGAAAGGGGAAAAGAGGTTTCTGCCACTTTACCCGACAGCGC
GTCATCTATCATTTTTAGGCAGAGTGAGAATAGGATGCATGTACAAAAGGCCTTGATGCTATTTTTGGATCAATAG

Upstream 100 bases:

>100_bases
GTATGCCTTTTCGTGATGCGCACCATCAAGTTGGGGCATGGATTGCAGAAGCGATAGAAAAACAATGTTCACTGAATGAA
TTATTAAAAGGAGGCTAAGA

Downstream 100 bases:

>100_bases
AACCTTGAGTTATGAGGCCCATATTAGTGTATAATGAAACGCTATTGCGCATTTCTCCTGATATGGGCTCATTATTTTTT
CAAATTAATTTAGTAATTCT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSFSTSTNLTPIEMQDDDLEKIQSQNNPSAINEVKTNTFVINLQQAIFGLETGSEAINLVSHKNTGFPFPAGEYKPRHFL
TGTELAREEIQFILSQARSLKQNPGLYNQALANKSLVMIFEKPSFRTRLSFALAIQSMGGLVVESIANSRKQETPADMAR
VLNGYADFVMVRTHEDRFLQEMAEYSKIPIINGLSALHHPCQTLADLLSLEEQFGALEGLTLTYIGDGNNILHSLMLLAP
QLGVTVHYCCPKSNQPNETIVKEAQSKAGKQMIYYFDKPEEAVKQADAVYTDVWTSMGFDNPEAGKIFKGFQVNETLMSH
AKPDSVFMHCMPMERGKEVSATLPDSASSIIFRQSENRMHVQKALMLFLDQ

Sequences:

>Translated_371_residues
MSFSTSTNLTPIEMQDDDLEKIQSQNNPSAINEVKTNTFVINLQQAIFGLETGSEAINLVSHKNTGFPFPAGEYKPRHFL
TGTELAREEIQFILSQARSLKQNPGLYNQALANKSLVMIFEKPSFRTRLSFALAIQSMGGLVVESIANSRKQETPADMAR
VLNGYADFVMVRTHEDRFLQEMAEYSKIPIINGLSALHHPCQTLADLLSLEEQFGALEGLTLTYIGDGNNILHSLMLLAP
QLGVTVHYCCPKSNQPNETIVKEAQSKAGKQMIYYFDKPEEAVKQADAVYTDVWTSMGFDNPEAGKIFKGFQVNETLMSH
AKPDSVFMHCMPMERGKEVSATLPDSASSIIFRQSENRMHVQKALMLFLDQ
>Mature_370_residues
SFSTSTNLTPIEMQDDDLEKIQSQNNPSAINEVKTNTFVINLQQAIFGLETGSEAINLVSHKNTGFPFPAGEYKPRHFLT
GTELAREEIQFILSQARSLKQNPGLYNQALANKSLVMIFEKPSFRTRLSFALAIQSMGGLVVESIANSRKQETPADMARV
LNGYADFVMVRTHEDRFLQEMAEYSKIPIINGLSALHHPCQTLADLLSLEEQFGALEGLTLTYIGDGNNILHSLMLLAPQ
LGVTVHYCCPKSNQPNETIVKEAQSKAGKQMIYYFDKPEEAVKQADAVYTDVWTSMGFDNPEAGKIFKGFQVNETLMSHA
KPDSVFMHCMPMERGKEVSATLPDSASSIIFRQSENRMHVQKALMLFLDQ

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=309, Percent_Identity=37.8640776699029, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI18105007, Length=263, Percent_Identity=31.1787072243346, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1786469, Length=326, Percent_Identity=33.7423312883436, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=32.6153846153846, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI2367364, Length=300, Percent_Identity=26, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI193204318, Length=336, Percent_Identity=26.7857142857143, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322373, Length=310, Percent_Identity=28.7096774193548, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322331, Length=303, Percent_Identity=26.4026402640264, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24642586, Length=280, Percent_Identity=30.3571428571429, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 41426; Mature: 41295

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSTSTNLTPIEMQDDDLEKIQSQNNPSAINEVKTNTFVINLQQAIFGLETGSEAINLV
CCCCCCCCCCEEECCCCHHHHHHCCCCCCHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHH
SHKNTGFPFPAGEYKPRHFLTGTELAREEIQFILSQARSLKQNPGLYNQALANKSLVMIF
HCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEE
EKPSFRTRLSFALAIQSMGGLVVESIANSRKQETPADMARVLNGYADFVMVRTHEDRFLQ
ECCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECHHHHHH
EMAEYSKIPIINGLSALHHPCQTLADLLSLEEQFGALEGLTLTYIGDGNNILHSLMLLAP
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
QLGVTVHYCCPKSNQPNETIVKEAQSKAGKQMIYYFDKPEEAVKQADAVYTDVWTSMGFD
HCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
NPEAGKIFKGFQVNETLMSHAKPDSVFMHCMPMERGKEVSATLPDSASSIIFRQSENRMH
CCCCCCEECCCCHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEECCCCHHH
VQKALMLFLDQ
HHHHHHHHHCC
>Mature Secondary Structure 
SFSTSTNLTPIEMQDDDLEKIQSQNNPSAINEVKTNTFVINLQQAIFGLETGSEAINLV
CCCCCCCCCEEECCCCHHHHHHCCCCCCHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHH
SHKNTGFPFPAGEYKPRHFLTGTELAREEIQFILSQARSLKQNPGLYNQALANKSLVMIF
HCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEE
EKPSFRTRLSFALAIQSMGGLVVESIANSRKQETPADMARVLNGYADFVMVRTHEDRFLQ
ECCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECHHHHHH
EMAEYSKIPIINGLSALHHPCQTLADLLSLEEQFGALEGLTLTYIGDGNNILHSLMLLAP
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
QLGVTVHYCCPKSNQPNETIVKEAQSKAGKQMIYYFDKPEEAVKQADAVYTDVWTSMGFD
HCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
NPEAGKIFKGFQVNETLMSHAKPDSVFMHCMPMERGKEVSATLPDSASSIIFRQSENRMH
CCCCCCEECCCCHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEECCCCHHH
VQKALMLFLDQ
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]