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The map label for this gene is fbaB

Identifier: 52787919

GI number: 52787919

Start: 4079615

End: 4080493

Strand: Reverse

Name: fbaB

Synonym: BLi04242

Alternate gene names: 52787919

Gene position: 4080493-4079615 (Counterclockwise)

Preceding gene: 52787920

Following gene: 52787918

Centisome position: 96.63

GC content: 49.03

Gene sequence:

>879_bases
GTGGCTTTCGTTTCCATGAAAGAACTTCTTCAAGAAGCAAAGGAACATCATTATGCAATCGGTCAATTTAATATTAATGG
CCTTCAATGGACAAAAGCGATTCTAGAGGCAGCGGAAGAAGAACGGTCACCTGTCATCGCAGCCGCTTCAGATCGGCTCA
TCGATTATTTGGGCGGATTTAAAACGGTTTCCGCAATGGTTGCGGCTTTGATTGAGGAAATGTCGATCTCCGTTCCCGTC
GTGCTTCACCTTGACCATGGCAAAAGTCCGGAGCGCTGCAAGCAAGCGATAGACGCGGGTTTTAGCTCAGTCATGATCGA
CGGCTCGCATTCACCAATCGATGAAAATATCGCCATGACAAAAGAGGTCGTGTCATATGCCGGGGTCCGCAATGTTTCGG
TTGAAGCAGAGGTTGGCACCGTAGGGGGCATGGAAGACGGGCTTATCGGCGGAGTGCAGTATGCCGACATCGGTGAATGC
GAGCGGATTGTCAAAGAAACCGGTATCGATGCTTTGGCAGCCGCGCTCGGCTCCGTTCATGGAAAATATCAAGGCGAGCC
TAATTTGGGATTTAAGGAAATGGAAGAAATCTCACGGGTAACGGACATTCCGCTCGTTCTCCATGGAGCTTCGGGCATCC
CGGCTGATCAAATCGCAAGAACGATCCGTCTGGGCCATGCGAAAATCAACATTAATACCGAATGCATGGTGGCCTGGACT
GAGAAAACGCGCAGCATATTTAAAGACAATCCCGATTTATATGAACCCCGCGCCTATATGACGCCAGGGATCAGCGCAGT
CAAAGAAACGGTTAAACATAAGATGAGAGAATTCGGGTCATCCGGAAAAGCGGTATGCACCCAAAAGATAGAAATATAA

Upstream 100 bases:

>100_bases
TAAGCTGAGCGCGGAAGAAACGATTCGAACGGCCAAAGAAACAACAGTTGAAGTTGTTTCAAAATACTTCAAGATTTAAT
ACGGGATAGGAGGGGTGAAC

Downstream 100 bases:

>100_bases
GCTAAACCAATATCGCCTCCACTCACTTAATCGAAGTGAGTGTTTTTTTGTTCGCAGTATTTGTAAAGATATTCTAAAGG
TTCAAAAGTATGATTGACTG

Product: hypothetical protein

Products: NA

Alternate protein names: DKGP aldolase

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAFVSMKELLQEAKEHHYAIGQFNINGLQWTKAILEAAEEERSPVIAAASDRLIDYLGGFKTVSAMVAALIEEMSISVPV
VLHLDHGKSPERCKQAIDAGFSSVMIDGSHSPIDENIAMTKEVVSYAGVRNVSVEAEVGTVGGMEDGLIGGVQYADIGEC
ERIVKETGIDALAAALGSVHGKYQGEPNLGFKEMEEISRVTDIPLVLHGASGIPADQIARTIRLGHAKININTECMVAWT
EKTRSIFKDNPDLYEPRAYMTPGISAVKETVKHKMREFGSSGKAVCTQKIEI

Sequences:

>Translated_292_residues
MAFVSMKELLQEAKEHHYAIGQFNINGLQWTKAILEAAEEERSPVIAAASDRLIDYLGGFKTVSAMVAALIEEMSISVPV
VLHLDHGKSPERCKQAIDAGFSSVMIDGSHSPIDENIAMTKEVVSYAGVRNVSVEAEVGTVGGMEDGLIGGVQYADIGEC
ERIVKETGIDALAAALGSVHGKYQGEPNLGFKEMEEISRVTDIPLVLHGASGIPADQIARTIRLGHAKININTECMVAWT
EKTRSIFKDNPDLYEPRAYMTPGISAVKETVKHKMREFGSSGKAVCTQKIEI
>Mature_291_residues
AFVSMKELLQEAKEHHYAIGQFNINGLQWTKAILEAAEEERSPVIAAASDRLIDYLGGFKTVSAMVAALIEEMSISVPVV
LHLDHGKSPERCKQAIDAGFSSVMIDGSHSPIDENIAMTKEVVSYAGVRNVSVEAEVGTVGGMEDGLIGGVQYADIGECE
RIVKETGIDALAAALGSVHGKYQGEPNLGFKEMEEISRVTDIPLVLHGASGIPADQIARTIRLGHAKININTECMVAWTE
KTRSIFKDNPDLYEPRAYMTPGISAVKETVKHKMREFGSSGKAVCTQKIEI

Specific function: Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily

Homologues:

Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=39.1608391608392, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=35.191637630662, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1788072, Length=280, Percent_Identity=37.5, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789293, Length=343, Percent_Identity=26.2390670553936, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=335, Percent_Identity=24.1791044776119, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLJ_BACLD (Q65D09)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_081314.1
- RefSeq:   YP_093748.1
- ProteinModelPortal:   Q65D09
- SMR:   Q65D09
- STRING:   Q65D09
- EnsemblBacteria:   EBBACT00000054288
- EnsemblBacteria:   EBBACT00000061434
- GeneID:   3030964
- GeneID:   3100047
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04242
- KEGG:   bli:BL00237
- NMPDR:   fig|279010.5.peg.3950
- eggNOG:   COG0191
- GeneTree:   EBGT00050000002241
- HOGENOM:   HBG327581
- OMA:   VGGMEDG
- ProtClustDB:   CLSK888173
- BioCyc:   BLIC279010-1:BLI04242-MONOMER
- BioCyc:   BLIC279010:BL00237-MONOMER
- GO:   GO:0006096
- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF001359
- TIGRFAMs:   TIGR00167
- TIGRFAMs:   TIGR01859

Pfam domain/function: PF01116 F_bP_aldolase

EC number: =4.1.2.29

Molecular weight: Translated: 31616; Mature: 31484

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00602 ALDOLASE_CLASS_II_1; PS00806 ALDOLASE_CLASS_II_2

Important sites: ACT_SITE 85-85 BINDING 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFVSMKELLQEAKEHHYAIGQFNINGLQWTKAILEAAEEERSPVIAAASDRLIDYLGGF
CCCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCH
KTVSAMVAALIEEMSISVPVVLHLDHGKSPERCKQAIDAGFSSVMIDGSHSPIDENIAMT
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
KEVVSYAGVRNVSVEAEVGTVGGMEDGLIGGVQYADIGECERIVKETGIDALAAALGSVH
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHC
GKYQGEPNLGFKEMEEISRVTDIPLVLHGASGIPADQIARTIRLGHAKININTECMVAWT
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCEEEEEEH
EKTRSIFKDNPDLYEPRAYMTPGISAVKETVKHKMREFGSSGKAVCTQKIEI
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure 
AFVSMKELLQEAKEHHYAIGQFNINGLQWTKAILEAAEEERSPVIAAASDRLIDYLGGF
CCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCH
KTVSAMVAALIEEMSISVPVVLHLDHGKSPERCKQAIDAGFSSVMIDGSHSPIDENIAMT
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
KEVVSYAGVRNVSVEAEVGTVGGMEDGLIGGVQYADIGECERIVKETGIDALAAALGSVH
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHC
GKYQGEPNLGFKEMEEISRVTDIPLVLHGASGIPADQIARTIRLGHAKININTECMVAWT
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCEEEEEEH
EKTRSIFKDNPDLYEPRAYMTPGISAVKETVKHKMREFGSSGKAVCTQKIEI
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA