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The map label for this gene is iolI

Identifier: 52787920

GI number: 52787920

Start: 4080515

End: 4081351

Strand: Reverse

Name: iolI

Synonym: BLi04243

Alternate gene names: 52787920

Gene position: 4081351-4080515 (Counterclockwise)

Preceding gene: 52787921

Following gene: 52787919

Centisome position: 96.65

GC content: 44.09

Gene sequence:

>837_bases
ATGAAGCTATGCTTTAATGAAGCAACGACGTTGGAAAATTCAAACCTTGCAAAAGACCTCGAATACTGTGAGAAGCACGG
ATACGATTATATCGAAATCCGGACGATGGATAAGCTGCCTGAGTACTTAAAAGACCATGCTCTCTCAGAGTTAGCCGAGT
ATTTTCAAACTCATCATATTAAGCCGCTGGCCTTGAATGCCCTTGTCTTTTTCAACAACCGCGATGAAAAAGGGCACCGT
GAAATCATCGAAGAATTTAAAGGCATGATGGAAACGTGCAAAATGCTTGGTGTGAAATACGTGGTCGCGGTACCGCTTGT
CACCGAACAAAAAATCTTAAAAGAAGATATTAAAGCAAGCTCCGTCGAAGTGCTGACAGAGCTGTCAGACATCGCTGAGC
CGTACGGCGTAAAGATCGCTGTCGAGTTTGTCGGTCACCCGGAGTGTACGGTCAATACGTTCAGCCAGGCCTATGACATC
GTCATGACCGTGAACCGCGATAATGTCGGCCTTGTTTTTGACAGCTTCCATTTCCATGCAATGGGCTCAAGTCTTGAGGA
TTTAAAAAAGGCGGACGGCAAGAAAATCTTCATTTATCATATCGATGACACGGAAGACTTTCCAATCGGATTTTTAAGAG
ATGAAGACCGTGTTTGGCCGGGACAGGGAGCCATCGACTTGGATGCCCACTTATCAACTTTGAAAGACATCGGTTTTTCG
GATGTCGTATCAGTTGAATTGTTCAGACCTGAATACTATAAGCTGAGCGCGGAAGAAACGATTCGAACGGCCAAAGAAAC
AACAGTTGAAGTTGTTTCAAAATACTTCAAGATTTAA

Upstream 100 bases:

>100_bases
TTGAAAAATTGAAACAAGAATTATTAGGCTAAGCCCCCCCCTGAGTTCGGCGCCCTGCCGAACTTCTCTTCACAAGGATA
TGAGAGAAGGAGAATCGAAT

Downstream 100 bases:

>100_bases
TACGGGATAGGAGGGGTGAACGTGGCTTTCGTTTCCATGAAAGAACTTCTTCAAGAAGCAAAGGAACATCATTATGCAAT
CGGTCAATTTAATATTAATG

Product: IolI

Products: NA

Alternate protein names: 2-keto-myo-inositol isomerase; 2KMI isomerase

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLCFNEATTLENSNLAKDLEYCEKHGYDYIEIRTMDKLPEYLKDHALSELAEYFQTHHIKPLALNALVFFNNRDEKGHR
EIIEEFKGMMETCKMLGVKYVVAVPLVTEQKILKEDIKASSVEVLTELSDIAEPYGVKIAVEFVGHPECTVNTFSQAYDI
VMTVNRDNVGLVFDSFHFHAMGSSLEDLKKADGKKIFIYHIDDTEDFPIGFLRDEDRVWPGQGAIDLDAHLSTLKDIGFS
DVVSVELFRPEYYKLSAEETIRTAKETTVEVVSKYFKI

Sequences:

>Translated_278_residues
MKLCFNEATTLENSNLAKDLEYCEKHGYDYIEIRTMDKLPEYLKDHALSELAEYFQTHHIKPLALNALVFFNNRDEKGHR
EIIEEFKGMMETCKMLGVKYVVAVPLVTEQKILKEDIKASSVEVLTELSDIAEPYGVKIAVEFVGHPECTVNTFSQAYDI
VMTVNRDNVGLVFDSFHFHAMGSSLEDLKKADGKKIFIYHIDDTEDFPIGFLRDEDRVWPGQGAIDLDAHLSTLKDIGFS
DVVSVELFRPEYYKLSAEETIRTAKETTVEVVSKYFKI
>Mature_278_residues
MKLCFNEATTLENSNLAKDLEYCEKHGYDYIEIRTMDKLPEYLKDHALSELAEYFQTHHIKPLALNALVFFNNRDEKGHR
EIIEEFKGMMETCKMLGVKYVVAVPLVTEQKILKEDIKASSVEVLTELSDIAEPYGVKIAVEFVGHPECTVNTFSQAYDI
VMTVNRDNVGLVFDSFHFHAMGSSLEDLKKADGKKIFIYHIDDTEDFPIGFLRDEDRVWPGQGAIDLDAHLSTLKDIGFS
DVVSVELFRPEYYKLSAEETIRTAKETTVEVVSKYFKI

Specific function: Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5/4,6- pentahydroxycyclohexanone)

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLI_BACLD (Q65D08)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_081315.1
- RefSeq:   YP_093749.1
- HSSP:   P42419
- ProteinModelPortal:   Q65D08
- SMR:   Q65D08
- STRING:   Q65D08
- EnsemblBacteria:   EBBACT00000054642
- EnsemblBacteria:   EBBACT00000060915
- GeneID:   3030951
- GeneID:   3097835
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04243
- KEGG:   bli:BL00238
- NMPDR:   fig|279010.5.peg.3951
- eggNOG:   COG1082
- GeneTree:   EBGT00050000002031
- HOGENOM:   HBG338492
- OMA:   HEITHEL
- ProtClustDB:   CLSK873286
- BioCyc:   BLIC279010-1:BLI04243-MONOMER
- BioCyc:   BLIC279010:BL00238-MONOMER
- InterPro:   IPR013022
- InterPro:   IPR012307
- Gene3D:   G3DSA:3.20.20.150

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: NA

Molecular weight: Translated: 31828; Mature: 31828

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCFNEATTLENSNLAKDLEYCEKHGYDYIEIRTMDKLPEYLKDHALSELAEYFQTHHI
CCEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
KPLALNALVFFNNRDEKGHREIIEEFKGMMETCKMLGVKYVVAVPLVTEQKILKEDIKAS
CEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHH
SVEVLTELSDIAEPYGVKIAVEFVGHPECTVNTFSQAYDIVMTVNRDNVGLVFDSFHFHA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHEEEEEEECCCCEEEEEECCCHHH
MGSSLEDLKKADGKKIFIYHIDDTEDFPIGFLRDEDRVWPGQGAIDLDAHLSTLKDIGFS
CCCCHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCC
DVVSVELFRPEYYKLSAEETIRTAKETTVEVVSKYFKI
CEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLCFNEATTLENSNLAKDLEYCEKHGYDYIEIRTMDKLPEYLKDHALSELAEYFQTHHI
CCEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
KPLALNALVFFNNRDEKGHREIIEEFKGMMETCKMLGVKYVVAVPLVTEQKILKEDIKAS
CEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHH
SVEVLTELSDIAEPYGVKIAVEFVGHPECTVNTFSQAYDIVMTVNRDNVGLVFDSFHFHA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHEEEEEEECCCCEEEEEECCCHHH
MGSSLEDLKKADGKKIFIYHIDDTEDFPIGFLRDEDRVWPGQGAIDLDAHLSTLKDIGFS
CCCCHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCC
DVVSVELFRPEYYKLSAEETIRTAKETTVEVVSKYFKI
CEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA