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The map label for this gene is yrvM [H]

Identifier: 52786613

GI number: 52786613

Start: 2769014

End: 2769778

Strand: Reverse

Name: yrvM [H]

Synonym: BLi02879

Alternate gene names: 52786613

Gene position: 2769778-2769014 (Counterclockwise)

Preceding gene: 52786614

Following gene: 52786611

Centisome position: 65.59

GC content: 46.27

Gene sequence:

>765_bases
TTGTTACATCAGTTTTCACGCAACGAATTAGCGATTGGAAAAGAAGGTTTAAATATTTTAAAAAACAGCACGGTCGCCGT
TTTGGGCGTCGGCGGGGTCGGTTCTTTCGCCGCGGAAGCGCTCGCCCGTTCAGGTGTCGGCAGAATCGTGATGGTCGATA
AAGACGATGTTGACATCACGAATGTCAACCGTCAGCTGCCTGCTTTACTTTCAACGGTCGGACAGCCGAAAGTTGACTTA
ATGAAAGCGAGAATCGCCGATATTAATCCGGAATGCGACGTCATCGCTTTAAAAATGTTCTATACCGAAGAGACGTATGA
ACAGTTTTTTGCATATGAACCGGATTATGTAATCGACGCTTCAGACACGATTCATTATAAAATCCACTTAATGAAAGAGT
GCCTGAAGCGCGGCATCAACATCATCTCAAGCATGGGAGCGGCCAATAAAACAGATCCGACAAGGTTTCAAGTGGCCGAT
ATTTCAAAAACCCACACCGATCCGATTGCAAAAGTCATCCGGACGAGGCTTCGCAAGGAAGGCATTACGAAAGGCATTAA
AGTCGTCTTTTCTGACGAAAGTCCGATCGTGATCCGTGAAGACGTACGCCAAGTCGTCGGAAATGATGAAGCGAAAATCC
GCAAAGCGCAGATGCCGCCGTCTTCAAATGCTTTTGTTCCGTCAGTCGCAGGCTTGATTATGGGCGGCCATGTGATCATG
GAGCTTTTGAAAGATATTCCGATCAAAAGGGTGAAAGATAAGTAA

Upstream 100 bases:

>100_bases
GCGAAAAAATATGACGGCAAAATGAAATAGACCGCTTGTTTAATCACCCGATTATGATAAGATACTATCGGTAACTGTTT
ATAAAGATGGAGTGAGATTC

Downstream 100 bases:

>100_bases
TACAAAAACGACAGCAGAGGTGCTGTCGTTTTTGGTTTCAAGACAAACGGCCTCCTTAATGAAAAGAAACAGGCCGTTTA
TTATTTTTGTTTCATCAGCT

Product: YrvM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLHQFSRNELAIGKEGLNILKNSTVAVLGVGGVGSFAAEALARSGVGRIVMVDKDDVDITNVNRQLPALLSTVGQPKVDL
MKARIADINPECDVIALKMFYTEETYEQFFAYEPDYVIDASDTIHYKIHLMKECLKRGINIISSMGAANKTDPTRFQVAD
ISKTHTDPIAKVIRTRLRKEGITKGIKVVFSDESPIVIREDVRQVVGNDEAKIRKAQMPPSSNAFVPSVAGLIMGGHVIM
ELLKDIPIKRVKDK

Sequences:

>Translated_254_residues
MLHQFSRNELAIGKEGLNILKNSTVAVLGVGGVGSFAAEALARSGVGRIVMVDKDDVDITNVNRQLPALLSTVGQPKVDL
MKARIADINPECDVIALKMFYTEETYEQFFAYEPDYVIDASDTIHYKIHLMKECLKRGINIISSMGAANKTDPTRFQVAD
ISKTHTDPIAKVIRTRLRKEGITKGIKVVFSDESPIVIREDVRQVVGNDEAKIRKAQMPPSSNAFVPSVAGLIMGGHVIM
ELLKDIPIKRVKDK
>Mature_254_residues
MLHQFSRNELAIGKEGLNILKNSTVAVLGVGGVGSFAAEALARSGVGRIVMVDKDDVDITNVNRQLPALLSTVGQPKVDL
MKARIADINPECDVIALKMFYTEETYEQFFAYEPDYVIDASDTIHYKIHLMKECLKRGINIISSMGAANKTDPTRFQVAD
ISKTHTDPIAKVIRTRLRKEGITKGIKVVFSDESPIVIREDVRQVVGNDEAKIRKAQMPPSSNAFVPSVAGLIMGGHVIM
ELLKDIPIKRVKDK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=206, Percent_Identity=38.8349514563107, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787048, Length=134, Percent_Identity=32.089552238806, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082356, Length=133, Percent_Identity=30.0751879699248, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321790, Length=202, Percent_Identity=36.6336633663366, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322825, Length=200, Percent_Identity=38.5, Blast_Score=128, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6321903, Length=147, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=142, Percent_Identity=30.2816901408451, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28003; Mature: 28003

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHQFSRNELAIGKEGLNILKNSTVAVLGVGGVGSFAAEALARSGVGRIVMVDKDDVDIT
CCCCCCCCCEEECHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCC
NVNRQLPALLSTVGQPKVDLMKARIADINPECDVIALKMFYTEETYEQFFAYEPDYVIDA
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEC
SDTIHYKIHLMKECLKRGINIISSMGAANKTDPTRFQVADISKTHTDPIAKVIRTRLRKE
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GITKGIKVVFSDESPIVIREDVRQVVGNDEAKIRKAQMPPSSNAFVPSVAGLIMGGHVIM
CCCCCEEEEECCCCCEEEHHHHHHHHCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
ELLKDIPIKRVKDK
HHHHHCCCHHCCCC
>Mature Secondary Structure
MLHQFSRNELAIGKEGLNILKNSTVAVLGVGGVGSFAAEALARSGVGRIVMVDKDDVDIT
CCCCCCCCCEEECHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCC
NVNRQLPALLSTVGQPKVDLMKARIADINPECDVIALKMFYTEETYEQFFAYEPDYVIDA
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEC
SDTIHYKIHLMKECLKRGINIISSMGAANKTDPTRFQVADISKTHTDPIAKVIRTRLRKE
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GITKGIKVVFSDESPIVIREDVRQVVGNDEAKIRKAQMPPSSNAFVPSVAGLIMGGHVIM
CCCCCEEEEECCCCCEEEHHHHHHHHCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
ELLKDIPIKRVKDK
HHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]