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The map label for this gene is cheR [H]

Identifier: 52786151

GI number: 52786151

Start: 2351075

End: 2351842

Strand: Reverse

Name: cheR [H]

Synonym: BLi02407

Alternate gene names: 52786151

Gene position: 2351842-2351075 (Counterclockwise)

Preceding gene: 52786152

Following gene: 52786150

Centisome position: 55.7

GC content: 40.49

Gene sequence:

>768_bases
ATGGACAATTACAGTTTCTTTGTTGATAAATGGAAAAAAATGACTGGTGTGGATTTGGCATTGTACAAAGAGGCGCAAAT
GAAAAGAAGACTGACGTCTCTATATGAGAAAAAAGGATACGGCGATTTCCGCGAGTTTGCGCTCGCTTTAGAAAAGAATG
AAGCTCTTCTGCAGGAAACATTGGACAGAATGACAATCAATGTTTCAGAATTTTACAGAAACTATAAGAGGTGGGAGGTT
CTCGAAAAAACGATCCTGCCGCTTTTAAAGCCTGCGAAAACGCTGAAAGTTTGGAGCGCGGCTTGTTCAACCGGGGAAGA
GCCTTATACATTATCAATGATTTTAAGCAGACAGAAAGGCCTCACAGACTATCAGATTATCGCAACAGATATCGATGACA
AAGTCCTTCAGAAAGCGAAAGAAGGCGTATATCAGGAAAGGTCCCTGCAGGAAGTGCCGAAAGAGATGAAAGAACTTTAT
TTTACGCAAGACGGAAACCGCTTTAAAGTCAAAGACGAGATCAGGAAAAACATCCGCTTTCAAAAGCACAATTTACTGGC
TGATCCGTATGAGAAAGATTTTGATATCATCGTATGCCGCAATGTGCTCATTTATTTTACGGAGGAAGCAAAAGAGAAGA
TCTATCATAAGTTCAGCGGCAGCCTGAAGAATAAGGGGATTTTGTTTGTCGGAAGCACGGAACAGATCTTCAATCCGGAA
AAATACGGTTTTCAATCGACAGATACGTTTTTCTATCAAAAAAGTTAG

Upstream 100 bases:

>100_bases
TGGCTGCCGGCGGGCGGGCTTTTTTCTTTTAAAGATACAAATTTAAAAGAAAACAAGCTATAATTGTACTCATATCAGCA
CGACGATTAGGAGAGAAAAC

Downstream 100 bases:

>100_bases
CTGACTTTTTATAAAGGGTTATGTTATAGTTTTACTTAAAAGCGTTAATGTGATGAAGGGAGAACGAAAGCATGAGGTAT
TTAACAGCCGGTGAATCTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDNYSFFVDKWKKMTGVDLALYKEAQMKRRLTSLYEKKGYGDFREFALALEKNEALLQETLDRMTINVSEFYRNYKRWEV
LEKTILPLLKPAKTLKVWSAACSTGEEPYTLSMILSRQKGLTDYQIIATDIDDKVLQKAKEGVYQERSLQEVPKEMKELY
FTQDGNRFKVKDEIRKNIRFQKHNLLADPYEKDFDIIVCRNVLIYFTEEAKEKIYHKFSGSLKNKGILFVGSTEQIFNPE
KYGFQSTDTFFYQKS

Sequences:

>Translated_255_residues
MDNYSFFVDKWKKMTGVDLALYKEAQMKRRLTSLYEKKGYGDFREFALALEKNEALLQETLDRMTINVSEFYRNYKRWEV
LEKTILPLLKPAKTLKVWSAACSTGEEPYTLSMILSRQKGLTDYQIIATDIDDKVLQKAKEGVYQERSLQEVPKEMKELY
FTQDGNRFKVKDEIRKNIRFQKHNLLADPYEKDFDIIVCRNVLIYFTEEAKEKIYHKFSGSLKNKGILFVGSTEQIFNPE
KYGFQSTDTFFYQKS
>Mature_255_residues
MDNYSFFVDKWKKMTGVDLALYKEAQMKRRLTSLYEKKGYGDFREFALALEKNEALLQETLDRMTINVSEFYRNYKRWEV
LEKTILPLLKPAKTLKVWSAACSTGEEPYTLSMILSRQKGLTDYQIIATDIDDKVLQKAKEGVYQERSLQEVPKEMKELY
FTQDGNRFKVKDEIRKNIRFQKHNLLADPYEKDFDIIVCRNVLIYFTEEAKEKIYHKFSGSLKNKGILFVGSTEQIFNPE
KYGFQSTDTFFYQKS

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=237, Percent_Identity=31.2236286919831, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 30184; Mature: 30184

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNYSFFVDKWKKMTGVDLALYKEAQMKRRLTSLYEKKGYGDFREFALALEKNEALLQET
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
LDRMTINVSEFYRNYKRWEVLEKTILPLLKPAKTLKVWSAACSTGEEPYTLSMILSRQKG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEHHHHHHHHCC
LTDYQIIATDIDDKVLQKAKEGVYQERSLQEVPKEMKELYFTQDGNRFKVKDEIRKNIRF
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCH
QKHNLLADPYEKDFDIIVCRNVLIYFTEEAKEKIYHKFSGSLKNKGILFVGSTEQIFNPE
HHHCCCCCCCCCCCCEEEECHHHHEEHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCH
KYGFQSTDTFFYQKS
HCCCCCCCCEEEECC
>Mature Secondary Structure
MDNYSFFVDKWKKMTGVDLALYKEAQMKRRLTSLYEKKGYGDFREFALALEKNEALLQET
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
LDRMTINVSEFYRNYKRWEVLEKTILPLLKPAKTLKVWSAACSTGEEPYTLSMILSRQKG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEHHHHHHHHCC
LTDYQIIATDIDDKVLQKAKEGVYQERSLQEVPKEMKELYFTQDGNRFKVKDEIRKNIRF
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCH
QKHNLLADPYEKDFDIIVCRNVLIYFTEEAKEKIYHKFSGSLKNKGILFVGSTEQIFNPE
HHHCCCCCCCCCCCCEEEECHHHHEEHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCH
KYGFQSTDTFFYQKS
HCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8244966; 9384377; 10568751 [H]