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The map label for this gene is panD

Identifier: 52786120

GI number: 52786120

Start: 2323193

End: 2323576

Strand: Reverse

Name: panD

Synonym: BLi02376

Alternate gene names: 52786120

Gene position: 2323576-2323193 (Counterclockwise)

Preceding gene: 52786121

Following gene: 52786119

Centisome position: 55.03

GC content: 49.22

Gene sequence:

>384_bases
ATGTACCGTACGTTAATGAGCGCAAAACTTCACAGAGCGAGAGTGACGGAAGCCAATTTGAACTACGTCGGCAGCGTGAC
AATTGATGAAGATTTGCTGGATGCTGTCGGAATGATGGCAAATGAAAAAGTGCAAATTGTGAATAATAATAACGGGGCCC
GGCTGGAAACGTACATTATTCCCGGTGAAAGGGGCAGCGGCGTCGTTTGTTTAAACGGAGCTGCCGCCCGCCTTGTCCAG
GTTGGAGATGTCGTCATCATCGTGTCTTATGCGATGATGTCTGAAGAGGAAGCAAAGACCCATAAGCCGAAGGTTGCCGT
TTTGAACGAGAGAAACGAAATCGAGGAAATGCTGGGTCAGGAGCCAGCCCGTACCATTCTGTAG

Upstream 100 bases:

>100_bases
CTGGAAAAGTCATCATAGCGGTTGCCGTTCAGTTTTCCAAAGCCCGCTTAATTGACAATATCATCGTCGATATCCCGGCA
GATCAAAAGGAGGATTTGTG

Downstream 100 bases:

>100_bases
CCCCCTTGCCTTTAGGGGGCTTTCATATCGTTTGGAAAGAGCGAAAGAGAAGAAGCCGGTTTTGAAGCTTTTCCCCCGCG
CCTTTTTAAAACGTGTTACA

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MYRTLMSAKLHRARVTEANLNYVGSVTIDEDLLDAVGMMANEKVQIVNNNNGARLETYIIPGERGSGVVCLNGAAARLVQ
VGDVVIIVSYAMMSEEEAKTHKPKVAVLNERNEIEEMLGQEPARTIL

Sequences:

>Translated_127_residues
MYRTLMSAKLHRARVTEANLNYVGSVTIDEDLLDAVGMMANEKVQIVNNNNGARLETYIIPGERGSGVVCLNGAAARLVQ
VGDVVIIVSYAMMSEEEAKTHKPKVAVLNERNEIEEMLGQEPARTIL
>Mature_127_residues
MYRTLMSAKLHRARVTEANLNYVGSVTIDEDLLDAVGMMANEKVQIVNNNNGARLETYIIPGERGSGVVCLNGAAARLVQ
VGDVVIIVSYAMMSEEEAKTHKPKVAVLNERNEIEEMLGQEPARTIL

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=122, Percent_Identity=47.5409836065574, Blast_Score=124, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_BACLD (Q65I58)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079540.1
- RefSeq:   YP_091949.1
- ProteinModelPortal:   Q65I58
- SMR:   Q65I58
- STRING:   Q65I58
- EnsemblBacteria:   EBBACT00000054328
- EnsemblBacteria:   EBBACT00000061243
- GeneID:   3029434
- GeneID:   3100408
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02376
- KEGG:   bli:BL02750
- NMPDR:   fig|279010.5.peg.226
- eggNOG:   COG0853
- GeneTree:   EBGT00050000002424
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- BioCyc:   BLIC279010-1:BLI02376-MONOMER
- BioCyc:   BLIC279010:BL02750-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 13929; Mature: 13929

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRTLMSAKLHRARVTEANLNYVGSVTIDEDLLDAVGMMANEKVQIVNNNNGARLETYII
CCCHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
PGERGSGVVCLNGAAARLVQVGDVVIIVSYAMMSEEEAKTHKPKVAVLNERNEIEEMLGQ
CCCCCCCEEEECCHHHHHHHHCCEEEEEHHHHHCCHHHHHCCCEEEEECCHHHHHHHHCC
EPARTIL
CCCCCCC
>Mature Secondary Structure
MYRTLMSAKLHRARVTEANLNYVGSVTIDEDLLDAVGMMANEKVQIVNNNNGARLETYII
CCCHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
PGERGSGVVCLNGAAARLVQVGDVVIIVSYAMMSEEEAKTHKPKVAVLNERNEIEEMLGQ
CCCCCCCEEEECCHHHHHHHHCCEEEEEHHHHHCCHHHHHCCCEEEEECCHHHHHHHHCC
EPARTIL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA