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The map label for this gene is fnr [H]

Identifier: 52785834

GI number: 52785834

Start: 2021649

End: 2022362

Strand: Reverse

Name: fnr [H]

Synonym: BLi02080

Alternate gene names: 52785834

Gene position: 2022362-2021649 (Counterclockwise)

Preceding gene: 52785835

Following gene: 52785832

Centisome position: 47.89

GC content: 44.4

Gene sequence:

>714_bases
ATGAACATTTCTGTTAGAAAATCAGACACAGATTTGCTCTCAGACGATCTGCATCACTTGCTGGAATCGATCAGTACGCG
ACGAAAAATCAGGCAGGACACATTCCTTTTTCAAGAAGGGATGGATGCAGAGGAACTGTATCTTATTCAGTCAGGACTTG
TCCAGATCGGCAAATTGACGTCCGATGGCAAAGAACTGACGCTTAGAATGTGCAAAAAAAATGATATTGTCGGGGAGCTT
ACGCTTTTTACAGAAGATGCGAAATATATGCTGAGCGCAAAGATCCTCTCTGATGGCGAAGTGTTGGTCATCAATAAAGA
TAAGCTTGAAAAAGAACTCATTCAAAACGGTGCGCTGACGTTTGAGTTTATGAAATGGATGAGCACGCATTTGCGAAAGA
TTCAATCGAAGATCCGCGACCTTTTGCTGAATGGTAAAAAAGGCGCGCTCTACTCCACCTTGATCCGTCTCGCAAACAGC
TACGGCATCACAAGAAGCGACGGGATTCTCATCAATATTGTCCTGACGAACCAGGATCTGGCGAAATTTTGTGCTGCTGC
AAGAGAAAGCATCAACCGCATGCTGAGCGACCTCCGGAAGAACGGTGTCATTTCAATTGAGGACTCGGGAAAAATCGTCA
TCCACCAGATCAATTATTTAAAACGCGAAATCGACTGTGAAAACTGCCCGCTCGAAATCTGCAATATCGACTGA

Upstream 100 bases:

>100_bases
TTCGGGACTATATTCATATGTTCACAATATTGTTTATATTTAAAAGGTCACTCTGCCTTATTTAACGTTAAAATAAGAAC
TGCAAAAGGGGTGACGCTCA

Downstream 100 bases:

>100_bases
AAAAGCGAAAACAAACAAGGACATGAAGCACAGTGTCCTTGTTTTTTACGTTTGCAGCAGAAAAACGATCAACACGGCCA
TAAAGATACAGGCATTCACC

Product: Fnr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNISVRKSDTDLLSDDLHHLLESISTRRKIRQDTFLFQEGMDAEELYLIQSGLVQIGKLTSDGKELTLRMCKKNDIVGEL
TLFTEDAKYMLSAKILSDGEVLVINKDKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLNGKKGALYSTLIRLANS
YGITRSDGILINIVLTNQDLAKFCAAARESINRMLSDLRKNGVISIEDSGKIVIHQINYLKREIDCENCPLEICNID

Sequences:

>Translated_237_residues
MNISVRKSDTDLLSDDLHHLLESISTRRKIRQDTFLFQEGMDAEELYLIQSGLVQIGKLTSDGKELTLRMCKKNDIVGEL
TLFTEDAKYMLSAKILSDGEVLVINKDKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLNGKKGALYSTLIRLANS
YGITRSDGILINIVLTNQDLAKFCAAARESINRMLSDLRKNGVISIEDSGKIVIHQINYLKREIDCENCPLEICNID
>Mature_237_residues
MNISVRKSDTDLLSDDLHHLLESISTRRKIRQDTFLFQEGMDAEELYLIQSGLVQIGKLTSDGKELTLRMCKKNDIVGEL
TLFTEDAKYMLSAKILSDGEVLVINKDKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLNGKKGALYSTLIRLANS
YGITRSDGILINIVLTNQDLAKFCAAARESINRMLSDLRKNGVISIEDSGKIVIHQINYLKREIDCENCPLEICNID

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=188, Percent_Identity=28.7234042553192, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26926; Mature: 26926

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISVRKSDTDLLSDDLHHLLESISTRRKIRQDTFLFQEGMDAEELYLIQSGLVQIGKLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SDGKELTLRMCKKNDIVGELTLFTEDAKYMLSAKILSDGEVLVINKDKLEKELIQNGALT
CCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHEEECCCCEEEEEHHHHHHHHHHCCCHH
FEFMKWMSTHLRKIQSKIRDLLLNGKKGALYSTLIRLANSYGITRSDGILINIVLTNQDL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHH
AKFCAAARESINRMLSDLRKNGVISIEDSGKIVIHQINYLKREIDCENCPLEICNID
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHCCCCCCCEEEECCC
>Mature Secondary Structure
MNISVRKSDTDLLSDDLHHLLESISTRRKIRQDTFLFQEGMDAEELYLIQSGLVQIGKLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SDGKELTLRMCKKNDIVGELTLFTEDAKYMLSAKILSDGEVLVINKDKLEKELIQNGALT
CCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHEEECCCCEEEEEHHHHHHHHHHCCCHH
FEFMKWMSTHLRKIQSKIRDLLLNGKKGALYSTLIRLANSYGITRSDGILINIVLTNQDL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHH
AKFCAAARESINRMLSDLRKNGVISIEDSGKIVIHQINYLKREIDCENCPLEICNID
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]