Click here to switch to the map view.

The map label for this gene is yhdH [H]

Identifier: 52784785

GI number: 52784785

Start: 1015964

End: 1017322

Strand: Direct

Name: yhdH [H]

Synonym: BLi01013

Alternate gene names: 52784785

Gene position: 1015964-1017322 (Clockwise)

Preceding gene: 52784784

Following gene: 52784786

Centisome position: 24.06

GC content: 49.23

Gene sequence:

>1359_bases
ATGAGCGACCGCAGAATGACAGCAAAGTGGGCATCCAAACTTGGATTTGTTCTCGCCGCCGCGGGGTCCGCCATCGGTCT
GGGAGCGATTTGGAAGTTTCCCTATGTGGCGGGAACGAGCGGGGGAGGCGCATTTTTCCTTGTGTTTGTCCTATTTACGA
TACTGCTGGGATACCCCCTGCTTTTGGGGGAATTTGTATTAGGCCGAAAAAGCCAATCGGACGCTATCGGCACCTATCAA
AAAATAGCGCCAGGGACGCCTTGGGTGATCACAGGCTGGATCGGAATCGCCGCCTGCTTCCTTGTCCTGTCGTTTTACAG
CGTGATCGGCGGCTGGATTTTGCTTTATATCATTAAAGCAGTAACCGGTTCATTGTCGGGTCTCACGCAGGCCGGATACG
GGGAGCTATTCGGTTCGATCATCCAAGATCCGCTGCAGACACTGGCAGCGCAGCTTGCGTTTATCATCATGACGATCCTC
GTCGTGGCGAAAGGTGTGCAAAAAGGAATCGAGCGCGTCAGTTCGATTATGATGCCGCTATTATTTATTTTATTTATTGC
GCTCGTTTTAAGGGCTCTGACGCTTGAGCATGCGATCGACGGCGTGCGTTTTCTGCTTGTGCCCGATTTTGGCAGCCTGA
CGCCGCAGGCGATTCTTTTTGCGCTCGGACAAGCTTTCTTTACACTGACGCTTGGCGTATCTGTGATGGTGACGTACAGC
TCCTATTTGTCAAAGTCACAAAACCTTCCGAAGTCGGCGCTGTCGATCGTGATCATGAACCTTGCCGTCACGCTGCTTGC
CGGCTTGGCGATTTTTCCGGCCGTCTTTTCATTCGGCCTTCAGCCGGATCAGGGGCCGACTTTATTATTTGCGGTTCTGC
CGGCAGTTTTTGACCGGCTTCCATTCGGGATGCTGTTTTTTATCGGATTTTTGACGGCCTTTTTATTCGCCGCCTTGACT
TCGGCTTTTTCGATGATCGAGATCATTGTTGCGGCCATTACAAAAGGCGACCAAACGAAAAGGGGAAAATGGACGTGGAC
GATCGGCCTTTTGATTTTTGCCGTCGGCATTCCTTCCTGCTTGTCTTACGGGATGCTTGATGAGCCGTTCATTTTTAAGA
AGACGTTTTTTGATGCGGCGGATTATGTCGTCAGCAATATTTTGATGCCGCTTGGCGCGCTCTTTATCTCCATTTTTATT
CCGCTGAAATTGTCCAAACACGATCTATATGAAGAGATGAAAAGCGGATCAAAAGCGGGGAAAGGCTTTTTTATCGTGTG
GTTTTATCTTCTTCGTTTCCTTGTTCCGCTTGCGATTGTACTTGTTTTTTTAAATTTAATCGGAGTGTTTTCATTTTAA

Upstream 100 bases:

>100_bases
TCTGTTTGTTTTTTCGGAAAAATAAGAATTTGAAAGACCACTTTCAAAAAAGCTGCCCCGTAAGAGATAATAGAAACAGA
AAGAGAAAGGATGTGTATGA

Downstream 100 bases:

>100_bases
AAGATCAGGAGATGGGTGAATATGGTGTTAGACTTTCAACAGATGTTTCCGAGCGAGGATGGCAATCACGAGGCGCGGTA
TCAGCTGCTGGCATTGCTTG

Product: YhdH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSDRRMTAKWASKLGFVLAAAGSAIGLGAIWKFPYVAGTSGGGAFFLVFVLFTILLGYPLLLGEFVLGRKSQSDAIGTYQ
KIAPGTPWVITGWIGIAACFLVLSFYSVIGGWILLYIIKAVTGSLSGLTQAGYGELFGSIIQDPLQTLAAQLAFIIMTIL
VVAKGVQKGIERVSSIMMPLLFILFIALVLRALTLEHAIDGVRFLLVPDFGSLTPQAILFALGQAFFTLTLGVSVMVTYS
SYLSKSQNLPKSALSIVIMNLAVTLLAGLAIFPAVFSFGLQPDQGPTLLFAVLPAVFDRLPFGMLFFIGFLTAFLFAALT
SAFSMIEIIVAAITKGDQTKRGKWTWTIGLLIFAVGIPSCLSYGMLDEPFIFKKTFFDAADYVVSNILMPLGALFISIFI
PLKLSKHDLYEEMKSGSKAGKGFFIVWFYLLRFLVPLAIVLVFLNLIGVFSF

Sequences:

>Translated_452_residues
MSDRRMTAKWASKLGFVLAAAGSAIGLGAIWKFPYVAGTSGGGAFFLVFVLFTILLGYPLLLGEFVLGRKSQSDAIGTYQ
KIAPGTPWVITGWIGIAACFLVLSFYSVIGGWILLYIIKAVTGSLSGLTQAGYGELFGSIIQDPLQTLAAQLAFIIMTIL
VVAKGVQKGIERVSSIMMPLLFILFIALVLRALTLEHAIDGVRFLLVPDFGSLTPQAILFALGQAFFTLTLGVSVMVTYS
SYLSKSQNLPKSALSIVIMNLAVTLLAGLAIFPAVFSFGLQPDQGPTLLFAVLPAVFDRLPFGMLFFIGFLTAFLFAALT
SAFSMIEIIVAAITKGDQTKRGKWTWTIGLLIFAVGIPSCLSYGMLDEPFIFKKTFFDAADYVVSNILMPLGALFISIFI
PLKLSKHDLYEEMKSGSKAGKGFFIVWFYLLRFLVPLAIVLVFLNLIGVFSF
>Mature_451_residues
SDRRMTAKWASKLGFVLAAAGSAIGLGAIWKFPYVAGTSGGGAFFLVFVLFTILLGYPLLLGEFVLGRKSQSDAIGTYQK
IAPGTPWVITGWIGIAACFLVLSFYSVIGGWILLYIIKAVTGSLSGLTQAGYGELFGSIIQDPLQTLAAQLAFIIMTILV
VAKGVQKGIERVSSIMMPLLFILFIALVLRALTLEHAIDGVRFLLVPDFGSLTPQAILFALGQAFFTLTLGVSVMVTYSS
YLSKSQNLPKSALSIVIMNLAVTLLAGLAIFPAVFSFGLQPDQGPTLLFAVLPAVFDRLPFGMLFFIGFLTAFLFAALTS
AFSMIEIIVAAITKGDQTKRGKWTWTIGLLIFAVGIPSCLSYGMLDEPFIFKKTFFDAADYVVSNILMPLGALFISIFIP
LKLSKHDLYEEMKSGSKAGKGFFIVWFYLLRFLVPLAIVLVFLNLIGVFSF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=376, Percent_Identity=27.1276595744681, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4507043, Length=374, Percent_Identity=27.5401069518717, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI33354281, Length=312, Percent_Identity=28.2051282051282, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI194018524, Length=334, Percent_Identity=28.1437125748503, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI58219014, Length=312, Percent_Identity=27.8846153846154, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184408, Length=384, Percent_Identity=26.3020833333333, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184406, Length=384, Percent_Identity=26.3020833333333, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184404, Length=384, Percent_Identity=26.3020833333333, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI188528618, Length=391, Percent_Identity=25.8312020460358, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI7657587, Length=461, Percent_Identity=24.0780911062907, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI51468073, Length=282, Percent_Identity=26.9503546099291, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4507041, Length=387, Percent_Identity=26.3565891472868, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI11181770, Length=290, Percent_Identity=26.2068965517241, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI134304856, Length=383, Percent_Identity=27.6762402088773, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI92859670, Length=441, Percent_Identity=24.9433106575964, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI197276623, Length=348, Percent_Identity=24.1379310344828, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI54607094, Length=348, Percent_Identity=24.1379310344828, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI12408638, Length=265, Percent_Identity=24.5283018867925, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI289191351, Length=403, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4557046, Length=403, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI289191377, Length=403, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI21361693, Length=119, Percent_Identity=36.1344537815126, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI5032097, Length=356, Percent_Identity=22.752808988764, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI197276625, Length=123, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI55749589, Length=292, Percent_Identity=22.6027397260274, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI300360519, Length=239, Percent_Identity=25.5230125523013, Blast_Score=66, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=391, Percent_Identity=23.7851662404092, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554804, Length=465, Percent_Identity=24.0860215053763, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25146584, Length=415, Percent_Identity=24.578313253012, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71995588, Length=402, Percent_Identity=24.1293532338308, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI133952791, Length=274, Percent_Identity=29.5620437956204, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=142, Percent_Identity=33.8028169014084, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71998244, Length=292, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115534083, Length=439, Percent_Identity=23.4624145785877, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17136952, Length=389, Percent_Identity=25.1928020565553, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281364394, Length=389, Percent_Identity=25.1928020565553, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574704, Length=389, Percent_Identity=25.1928020565553, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136950, Length=389, Percent_Identity=25.1928020565553, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574702, Length=389, Percent_Identity=25.1928020565553, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45550877, Length=414, Percent_Identity=26.0869565217391, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI45551183, Length=414, Percent_Identity=26.3285024154589, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24762620, Length=388, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24639514, Length=506, Percent_Identity=23.3201581027668, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639516, Length=300, Percent_Identity=27, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221329674, Length=506, Percent_Identity=23.3201581027668, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281364136, Length=396, Percent_Identity=25.5050505050505, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24661428, Length=365, Percent_Identity=25.2054794520548, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655079, Length=296, Percent_Identity=26.6891891891892, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24582567, Length=385, Percent_Identity=26.4935064935065, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45551088, Length=349, Percent_Identity=25.214899713467, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652942, Length=349, Percent_Identity=25.214899713467, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639853, Length=328, Percent_Identity=22.2560975609756, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654186, Length=285, Percent_Identity=25.6140350877193, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48973; Mature: 48842

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDRRMTAKWASKLGFVLAAAGSAIGLGAIWKFPYVAGTSGGGAFFLVFVLFTILLGYPL
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]