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The map label for this gene is ddc [H]

Identifier: 52784786

GI number: 52784786

Start: 1017344

End: 1018972

Strand: Direct

Name: ddc [H]

Synonym: BLi01014

Alternate gene names: 52784786

Gene position: 1017344-1018972 (Clockwise)

Preceding gene: 52784785

Following gene: 52784789

Centisome position: 24.09

GC content: 49.79

Gene sequence:

>1629_bases
ATGGTGTTAGACTTTCAACAGATGTTTCCGAGCGAGGATGGCAATCACGAGGCGCGGTATCAGCTGCTGGCATTGCTTGA
AGCGGTATTGGCCGGAATGGACAGGCTGAAGGATCCCGGCCGGCTGACGCTTGGCCGCGAGTCTGAAGTTTCATCTGACT
ACTATCAAAGCGTCATTGAAGAGGCCGTCTTGCCGGAAAAAGGCTTCGGGGCGGAAAAAAGCGTTGAAGAGCTATTGAAA
TTGCTTGACGGCCACCGCTTTTTAAACAGGCATTATGTGGCCAACGCGACGCCTCTGCCGAACAACGCCAGCATCGCCGG
GAATCTTTTAATGGTTCTTTTAAACGGAAACAATTTATGGGATGTCGACGGCACGGCTGCAGCCAGGACGGAAGTGCAGA
TCACGGCGATGCTTTCTGATATTGTCGGCTATGACAGGCACAAGAGCGGCGGTTTTACAACCTGGGGCGGGCAGGGAGCC
GTTTTTCAGTCGCTCAGGCTGGCGATCGCAAACGCGTACCCTGAAGCGAATCAGCAAGGAACGCCGCATCATCTGTACGC
GTTCTGTTCAGAGCTTTCGCATTTCAGCCTTTATAAGTCGATGGAAGCTTCCGGAATCGGGACGGACCATTTGATCAAGG
TCAAGACGAATCACGATCATTCGATGGATCTGGCCGATTTGCGGGAAAAAATGCAAGCCGTGATTGAAAAAGGCGGACAT
CCGATTTATGTATTGGCAACGCTTGGCACAACCGACGCATTTGGCATCGATGATTTGGCCGGAATCAAGAACGTGACTGA
AGAAATAGAGGCCGCATACGGTTTGCCGCCTGTTTATATTCATGCCGATACGGCGATGGGCGGGATGTACAGCTTTTTTA
ACGGATACGATTTCTCCGGCAATCCGCTGCATATTGAAGATGAGGTGCTTGAGACGCTTGCCCGCTACAAACAACATTTT
CAGCATTTGCACCTGGCGGACAGCTTGGTCTTTGATTTTCATAAACTCGGACAAACGCCGTATATCACAAGCCTTTTCTT
GGTGAAAAACCGCAAGGCATTGCAGGCTGTTGATTTGGATCCGGATGAGACGCCTTATGTCGGCAACAGAGGGTTTGGCA
GCTATCATACGAGCTATACGCTAGAGTGTTCGCGAATGGGAAGCAGCATACCGATTTATGCTTCTCTGCTCGCATTTGGA
ATCGAAGGCTACCAGGAGATCTTGGCCAATTACATCAGGGTTAACCTGGCGTTTCGAAAAAAACTGCTGCAGGCTTTTCC
GAATGCAGCCGTCACCAATGATGTATCACCTGTGACGACATTCCGCTTCTATCCGGGAAATGTCCGCTATCACGAAGAAA
TCAGCGGCGCCATCACGGAGGAAGAAGTGCGGAATATTAACAAATACAATGAGAAAATCGCCGAAACATTGGGAAGGTAC
CGCAGTCACACCTATTTCGGCAGCACGAAAAAGCAAACATACGTTTATCCTGCTGACAGCCGTTTGCCAGTGCCGCTTTA
TGTCCAGAAATTCTACAGTGTCTCGCCTTACACGACGGTTGATACAACTGATCAATATATCGCCTTTTTAAAAGCGCATG
TTGAAACGTCGGATGTAGCGGCTGGATAA

Upstream 100 bases:

>100_bases
GTTTTATCTTCTTCGTTTCCTTGTTCCGCTTGCGATTGTACTTGTTTTTTTAAATTTAATCGGAGTGTTTTCATTTTAAA
AGATCAGGAGATGGGTGAAT

Downstream 100 bases:

>100_bases
AATAAAGAACAGGAGGTTTGAACCTCCCGTTCTTTATTTAGTTCTTACATGCCGTTCTTTTTTGAACCGGTATCCATATT
TCGCTTTTAAACGTTGGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MVLDFQQMFPSEDGNHEARYQLLALLEAVLAGMDRLKDPGRLTLGRESEVSSDYYQSVIEEAVLPEKGFGAEKSVEELLK
LLDGHRFLNRHYVANATPLPNNASIAGNLLMVLLNGNNLWDVDGTAAARTEVQITAMLSDIVGYDRHKSGGFTTWGGQGA
VFQSLRLAIANAYPEANQQGTPHHLYAFCSELSHFSLYKSMEASGIGTDHLIKVKTNHDHSMDLADLREKMQAVIEKGGH
PIYVLATLGTTDAFGIDDLAGIKNVTEEIEAAYGLPPVYIHADTAMGGMYSFFNGYDFSGNPLHIEDEVLETLARYKQHF
QHLHLADSLVFDFHKLGQTPYITSLFLVKNRKALQAVDLDPDETPYVGNRGFGSYHTSYTLECSRMGSSIPIYASLLAFG
IEGYQEILANYIRVNLAFRKKLLQAFPNAAVTNDVSPVTTFRFYPGNVRYHEEISGAITEEEVRNINKYNEKIAETLGRY
RSHTYFGSTKKQTYVYPADSRLPVPLYVQKFYSVSPYTTVDTTDQYIAFLKAHVETSDVAAG

Sequences:

>Translated_542_residues
MVLDFQQMFPSEDGNHEARYQLLALLEAVLAGMDRLKDPGRLTLGRESEVSSDYYQSVIEEAVLPEKGFGAEKSVEELLK
LLDGHRFLNRHYVANATPLPNNASIAGNLLMVLLNGNNLWDVDGTAAARTEVQITAMLSDIVGYDRHKSGGFTTWGGQGA
VFQSLRLAIANAYPEANQQGTPHHLYAFCSELSHFSLYKSMEASGIGTDHLIKVKTNHDHSMDLADLREKMQAVIEKGGH
PIYVLATLGTTDAFGIDDLAGIKNVTEEIEAAYGLPPVYIHADTAMGGMYSFFNGYDFSGNPLHIEDEVLETLARYKQHF
QHLHLADSLVFDFHKLGQTPYITSLFLVKNRKALQAVDLDPDETPYVGNRGFGSYHTSYTLECSRMGSSIPIYASLLAFG
IEGYQEILANYIRVNLAFRKKLLQAFPNAAVTNDVSPVTTFRFYPGNVRYHEEISGAITEEEVRNINKYNEKIAETLGRY
RSHTYFGSTKKQTYVYPADSRLPVPLYVQKFYSVSPYTTVDTTDQYIAFLKAHVETSDVAAG
>Mature_542_residues
MVLDFQQMFPSEDGNHEARYQLLALLEAVLAGMDRLKDPGRLTLGRESEVSSDYYQSVIEEAVLPEKGFGAEKSVEELLK
LLDGHRFLNRHYVANATPLPNNASIAGNLLMVLLNGNNLWDVDGTAAARTEVQITAMLSDIVGYDRHKSGGFTTWGGQGA
VFQSLRLAIANAYPEANQQGTPHHLYAFCSELSHFSLYKSMEASGIGTDHLIKVKTNHDHSMDLADLREKMQAVIEKGGH
PIYVLATLGTTDAFGIDDLAGIKNVTEEIEAAYGLPPVYIHADTAMGGMYSFFNGYDFSGNPLHIEDEVLETLARYKQHF
QHLHLADSLVFDFHKLGQTPYITSLFLVKNRKALQAVDLDPDETPYVGNRGFGSYHTSYTLECSRMGSSIPIYASLLAFG
IEGYQEILANYIRVNLAFRKKLLQAFPNAAVTNDVSPVTTFRFYPGNVRYHEEISGAITEEEVRNINKYNEKIAETLGRY
RSHTYFGSTKKQTYVYPADSRLPVPLYVQKFYSVSPYTTVDTTDQYIAFLKAHVETSDVAAG

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=272, Percent_Identity=24.6323529411765, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4503875, Length=272, Percent_Identity=24.6323529411765, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI58331246, Length=334, Percent_Identity=25.1497005988024, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136594, Length=332, Percent_Identity=25.9036144578313, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356415, Length=363, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 60386; Mature: 60386

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDFQQMFPSEDGNHEARYQLLALLEAVLAGMDRLKDPGRLTLGRESEVSSDYYQSVIE
CEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHH
EAVLPEKGFGAEKSVEELLKLLDGHRFLNRHYVANATPLPNNASIAGNLLMVLLNGNNLW
HHCCCCCCCCCHHHHHHHHHHHCCHHHHHHCEECCCCCCCCCCCCCCEEEEEEECCCEEE
DVDGTAAARTEVQITAMLSDIVGYDRHKSGGFTTWGGQGAVFQSLRLAIANAYPEANQQG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
TPHHLYAFCSELSHFSLYKSMEASGIGTDHLIKVKTNHDHSMDLADLREKMQAVIEKGGH
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
PIYVLATLGTTDAFGIDDLAGIKNVTEEIEAAYGLPPVYIHADTAMGGMYSFFNGYDFSG
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCHHHHHHCCCCCCC
NPLHIEDEVLETLARYKQHFQHLHLADSLVFDFHKLGQTPYITSLFLVKNRKALQAVDLD
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHEEECCC
PDETPYVGNRGFGSYHTSYTLECSRMGSSIPIYASLLAFGIEGYQEILANYIRVNLAFRK
CCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLQAFPNAAVTNDVSPVTTFRFYPGNVRYHEEISGAITEEEVRNINKYNEKIAETLGRY
HHHHHCCCCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RSHTYFGSTKKQTYVYPADSRLPVPLYVQKFYSVSPYTTVDTTDQYIAFLKAHVETSDVA
HCCCEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC
AG
CC
>Mature Secondary Structure
MVLDFQQMFPSEDGNHEARYQLLALLEAVLAGMDRLKDPGRLTLGRESEVSSDYYQSVIE
CEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHH
EAVLPEKGFGAEKSVEELLKLLDGHRFLNRHYVANATPLPNNASIAGNLLMVLLNGNNLW
HHCCCCCCCCCHHHHHHHHHHHCCHHHHHHCEECCCCCCCCCCCCCCEEEEEEECCCEEE
DVDGTAAARTEVQITAMLSDIVGYDRHKSGGFTTWGGQGAVFQSLRLAIANAYPEANQQG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
TPHHLYAFCSELSHFSLYKSMEASGIGTDHLIKVKTNHDHSMDLADLREKMQAVIEKGGH
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
PIYVLATLGTTDAFGIDDLAGIKNVTEEIEAAYGLPPVYIHADTAMGGMYSFFNGYDFSG
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCHHHHHHCCCCCCC
NPLHIEDEVLETLARYKQHFQHLHLADSLVFDFHKLGQTPYITSLFLVKNRKALQAVDLD
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHEEECCC
PDETPYVGNRGFGSYHTSYTLECSRMGSSIPIYASLLAFGIEGYQEILANYIRVNLAFRK
CCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLQAFPNAAVTNDVSPVTTFRFYPGNVRYHEEISGAITEEEVRNINKYNEKIAETLGRY
HHHHHCCCCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RSHTYFGSTKKQTYVYPADSRLPVPLYVQKFYSVSPYTTVDTTDQYIAFLKAHVETSDVA
HCCCEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]