Click here to switch to the map view.

The map label for this gene is yrbE [H]

Identifier: 52784608

GI number: 52784608

Start: 827465

End: 828529

Strand: Direct

Name: yrbE [H]

Synonym: BLi00809

Alternate gene names: 52784608

Gene position: 827465-828529 (Clockwise)

Preceding gene: 52784607

Following gene: 52784609

Centisome position: 19.6

GC content: 49.58

Gene sequence:

>1065_bases
GTGACGGTTCATTTTGGTTTAATCGGCTGCGGCTATATGTCAAGAAAACATCTTCAAGCACTGGCCGAGTGCGATGATGC
AAAGTTGTCGGCCGTCAGTGATTTGCAGGAAGAAAGAATGAAGGAAGCGGAAGAATACTATGCTTCCCTCGCCGGTGAGG
AAAGCCGAATGACCCGCTATCCGCAGTATCAAGCGCTGCTTTCAGATCCTAAAATTGAAGCGGTCATTATTGCGGCGGTT
TCGGGACTGCACGCCGAAATGGCCAAACATGCGCTGCTGGCAGGCAAGCACGTCATCGTCGAAAAACCGATGACCTTGTC
ATTACGGGATGCCGATGAGCTTATAGAACTGGCGGAGCAGAACGGGCTGAAGCTCATGGTCTGCCACCAGATGCGCCACC
GGCCGATCATGAAAAAACTGAAGGAAACGATTGAGGAAGGAAAGCTGGGAAAGATCTACTTGGGCACGGTATCGCTCCGC
TTAAACAGGTCCCCCGCTTATTATGAAGCGGCATCCTGGCGGGGAAGCTGGGAAAAAGACGGCGGGATGCTGGTCAATCA
AGGGATACATCTGATCGATCTGCTGCAATGGTTTTTAGGTGATGTAAAAGGCGTTTACGGAGATATGCTGGGCGGCTCCG
GAGCTAAAGAAACGGAAGATGTTGCTGTCGGTATTCTGACGTTTGCCAGTCAGGCGAAAGGTGTAGTAGAAGCGAATATC
GTCACACAGCCAAACAATATCGGAAGCTCTCTCTCGATTTTTGGAGAAAATGGAACGATTTCATTGGAAGGTCCGGCATT
AAACCGGATCAGCCGCTGGTACATCCACGGGGAGAAGGCGGATGCTGAAGAAGCGGCAAAGCTGATTGACATCGGCGGCG
AACAAACCGCAATGTATCAAAACTTTATAAGCGCCCTCAAGCGCCAAGACACGCTATTGGTTGACGGCTATGAAGGAAAA
AAGGCGATTGAAACCATCTTTGGAATCTATCAATCTGTGCTGCAGAAGCAACCGGTGCAGCTGCCTCTTTCTTCATTTCA
AACAACTGATATGAAAAATAAATAG

Upstream 100 bases:

>100_bases
TGTCCGAAACCCTTTTCGCCATTCCGATGGATCCTTTTCTAGCCGCCGAGGAACAAGATCAGATTATTTCTGCGCTGCTG
AAAAAAGGAGGAGGGGAAAA

Downstream 100 bases:

>100_bases
GTTTTGTTTTGGTAGATCGTCCCTTTCAAAAAAAGATTTGAAACATAGTTTATTAAAGGAATGTACAGAAGGGGCGAGTT
GATAAATGAGCAAACAGGAA

Product: YrbE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTVHFGLIGCGYMSRKHLQALAECDDAKLSAVSDLQEERMKEAEEYYASLAGEESRMTRYPQYQALLSDPKIEAVIIAAV
SGLHAEMAKHALLAGKHVIVEKPMTLSLRDADELIELAEQNGLKLMVCHQMRHRPIMKKLKETIEEGKLGKIYLGTVSLR
LNRSPAYYEAASWRGSWEKDGGMLVNQGIHLIDLLQWFLGDVKGVYGDMLGGSGAKETEDVAVGILTFASQAKGVVEANI
VTQPNNIGSSLSIFGENGTISLEGPALNRISRWYIHGEKADAEEAAKLIDIGGEQTAMYQNFISALKRQDTLLVDGYEGK
KAIETIFGIYQSVLQKQPVQLPLSSFQTTDMKNK

Sequences:

>Translated_354_residues
MTVHFGLIGCGYMSRKHLQALAECDDAKLSAVSDLQEERMKEAEEYYASLAGEESRMTRYPQYQALLSDPKIEAVIIAAV
SGLHAEMAKHALLAGKHVIVEKPMTLSLRDADELIELAEQNGLKLMVCHQMRHRPIMKKLKETIEEGKLGKIYLGTVSLR
LNRSPAYYEAASWRGSWEKDGGMLVNQGIHLIDLLQWFLGDVKGVYGDMLGGSGAKETEDVAVGILTFASQAKGVVEANI
VTQPNNIGSSLSIFGENGTISLEGPALNRISRWYIHGEKADAEEAAKLIDIGGEQTAMYQNFISALKRQDTLLVDGYEGK
KAIETIFGIYQSVLQKQPVQLPLSSFQTTDMKNK
>Mature_353_residues
TVHFGLIGCGYMSRKHLQALAECDDAKLSAVSDLQEERMKEAEEYYASLAGEESRMTRYPQYQALLSDPKIEAVIIAAVS
GLHAEMAKHALLAGKHVIVEKPMTLSLRDADELIELAEQNGLKLMVCHQMRHRPIMKKLKETIEEGKLGKIYLGTVSLRL
NRSPAYYEAASWRGSWEKDGGMLVNQGIHLIDLLQWFLGDVKGVYGDMLGGSGAKETEDVAVGILTFASQAKGVVEANIV
TQPNNIGSSLSIFGENGTISLEGPALNRISRWYIHGEKADAEEAAKLIDIGGEQTAMYQNFISALKRQDTLLVDGYEGKK
AIETIFGIYQSVLQKQPVQLPLSSFQTTDMKNK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87081947, Length=203, Percent_Identity=29.5566502463054, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082405, Length=234, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789848, Length=144, Percent_Identity=31.25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787574, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=280, Percent_Identity=25, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39037; Mature: 38906

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFGLIGCGYMSRKHLQALAECDDAKLSAVSDLQEERMKEAEEYYASLAGEESRMTRY
CEEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
PQYQALLSDPKIEAVIIAAVSGLHAEMAKHALLAGKHVIVEKPMTLSLRDADELIELAEQ
CHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHC
NGLKLMVCHQMRHRPIMKKLKETIEEGKLGKIYLGTVSLRLNRSPAYYEAASWRGSWEKD
CCCEEEEHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEHHCCCCCCCCC
GGMLVNQGIHLIDLLQWFLGDVKGVYGDMLGGSGAKETEDVAVGILTFASQAKGVVEANI
CCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VTQPNNIGSSLSIFGENGTISLEGPALNRISRWYIHGEKADAEEAAKLIDIGGEQTAMYQ
EECCCCCCCCEEEEECCCEEEECCCHHHHHHHEEEECCCCCHHHHHHHHHCCCCHHHHHH
NFISALKRQDTLLVDGYEGKKAIETIFGIYQSVLQKQPVQLPLSSFQTTDMKNK
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
TVHFGLIGCGYMSRKHLQALAECDDAKLSAVSDLQEERMKEAEEYYASLAGEESRMTRY
EEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
PQYQALLSDPKIEAVIIAAVSGLHAEMAKHALLAGKHVIVEKPMTLSLRDADELIELAEQ
CHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHC
NGLKLMVCHQMRHRPIMKKLKETIEEGKLGKIYLGTVSLRLNRSPAYYEAASWRGSWEKD
CCCEEEEHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEHHCCCCCCCCC
GGMLVNQGIHLIDLLQWFLGDVKGVYGDMLGGSGAKETEDVAVGILTFASQAKGVVEANI
CCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VTQPNNIGSSLSIFGENGTISLEGPALNRISRWYIHGEKADAEEAAKLIDIGGEQTAMYQ
EECCCCCCCCEEEEECCCEEEECCCHHHHHHHEEEECCCCCHHHHHHHHHCCCCHHHHHH
NFISALKRQDTLLVDGYEGKKAIETIFGIYQSVLQKQPVQLPLSSFQTTDMKNK
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]