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The map label for this gene is yrbE [H]

Identifier: 52142988

GI number: 52142988

Start: 2381199

End: 2382224

Strand: Direct

Name: yrbE [H]

Synonym: BCZK2251

Alternate gene names: 52142988

Gene position: 2381199-2382224 (Clockwise)

Preceding gene: 52142990

Following gene: 52142986

Centisome position: 44.92

GC content: 37.82

Gene sequence:

>1026_bases
ATGAACGTTTTAACAATTGGGATTATTGGTGCTGGACGAATTGGGAAACTACATGTTGATAATTTGCAGCTTATGCCACA
AGTAAAAATTAAAGCGGTTTCAGATGTAGTAATTGGTCATCTAGAAAAGTGGGCTCAAGATAAAGGAATTTCCACTCTGA
CTACAAACTATCAGGATTTATTAGCAGATCCAGAAATTGATGCTGTCTTTATTTGTTCACCAACAAATACACATGCGCAA
ATTATTAAAGAAGCGGCTCTTGCGAAAAAACATATTTTCTGTGAAAAGCCTGTTAGTTTCTCAGTAGAAGAAACATTAGA
AGCATTAGAAGTGGTGAAAGAACAGGGGGTATCTCTTCAAGTAGGTTTTAATCGTCGTTTTGATCCGAACTTCAGGAAAG
TCTATGATCTTATTCAACAAGGAGAAGTGGGACAGCTGCATATTTTAAAAATTACGTCACGCGATCCACAACCGCCAAGT
ATAGAATATGTTCGCTCTTCAGGCGGATTGTTTATGGATATGATGATTCATGATTTTGATATGGCTCGTTATGTGATGAA
TAGTGAAGTCGTTGAAGTATTTGCATATGGAACAACATTAATTGATCCATCCATTCAGGAAGTAAATGATGTTGATACTG
CAATTGTCACATTAAAATTTGCGAATGGAGCTTTAGGTGTAATTGATAATAGCCGCCAAGCTGTTTATGGATATGACCAG
CGTGTGGAAGTGTTTGGTGAAAAAGGCGCGGTTGCTGCGGATAATTGCTGCCCGACAACAGTTCAAGTGTCAAAAACAGA
AGGTATTGTAAAAGATAAGCCGCTTTATTTCTTCTTAGAGCGTTACACGCAGGCTTACATTGAGGAAGTAACACAATTTA
CAAAGTCAATTATAGAAGGGCAAGCTGTTATTTGCAGTGGTAATAATGGGTTACAAGCGGAGCGAATTGCGAAAGCTGCG
AAGGAATCCTTACTAACAGGAAAACCCGTACAAATTCAACATAAACAGCCTGCATTAAATCAATAA

Upstream 100 bases:

>100_bases
AATGAAGAAAAATAGGGAAAGCGCTTAACTTAATTTAATACGCTAAACCCTATAGACTTTCATTTCGTTTCTTAAATTTT
AATATAGAGGGAGAAATCAT

Downstream 100 bases:

>100_bases
AGAGAGCGCTTACTTATAGATAGATAAAGAGTAATGAATAGTATATTTATAAAAATATGAACCTTATCATTCATTCATAA
AGCATGGGAGGTAGTAACAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNVLTIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLTTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQLHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVNDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTQAYIEEVTQFTKSIIEGQAVICSGNNGLQAERIAKAA
KESLLTGKPVQIQHKQPALNQ

Sequences:

>Translated_341_residues
MNVLTIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLTTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQLHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVNDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTQAYIEEVTQFTKSIIEGQAVICSGNNGLQAERIAKAA
KESLLTGKPVQIQHKQPALNQ
>Mature_341_residues
MNVLTIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLTTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQLHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVNDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTQAYIEEVTQFTKSIIEGQAVICSGNNGLQAERIAKAA
KESLLTGKPVQIQHKQPALNQ

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=257, Percent_Identity=24.124513618677, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787574, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081947, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24581117, Length=200, Percent_Identity=22.5, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37722; Mature: 37722

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLTIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLTTNYQDL
CCEEEEEEECCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
LADPEIDAVFICSPTNTHAQIIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQ
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEE
VGFNRRFDPNFRKVYDLIQQGEVGQLHILKITSRDPQPPSIEYVRSSGGLFMDMMIHDFD
ECCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHEEECCCCEEEEHHHHHHH
MARYVMNSEVVEVFAYGTTLIDPSIQEVNDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
HHHHHHHHHHHHHHHHCCEEECCCHHHHHCCCEEEEEEEECCCEEEEEECCCCEEECCCC
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTQAYIEEVTQFTKSIIEG
EEEEECCCCCEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QAVICSGNNGLQAERIAKAAKESLLTGKPVQIQHKQPALNQ
CEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MNVLTIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLTTNYQDL
CCEEEEEEECCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
LADPEIDAVFICSPTNTHAQIIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQ
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEE
VGFNRRFDPNFRKVYDLIQQGEVGQLHILKITSRDPQPPSIEYVRSSGGLFMDMMIHDFD
ECCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHEEECCCCEEEEHHHHHHH
MARYVMNSEVVEVFAYGTTLIDPSIQEVNDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
HHHHHHHHHHHHHHHHCCEEECCCHHHHHCCCEEEEEEEECCCEEEEEECCCCEEECCCC
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTQAYIEEVTQFTKSIIEG
EEEEECCCCCEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QAVICSGNNGLQAERIAKAAKESLLTGKPVQIQHKQPALNQ
CEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]