Click here to switch to the map view.

The map label for this gene is iolC

Identifier: 52142986

GI number: 52142986

Start: 2382324

End: 2383322

Strand: Direct

Name: iolC

Synonym: BCZK2252

Alternate gene names: 52142986

Gene position: 2382324-2383322 (Clockwise)

Preceding gene: 52142988

Following gene: 52142987

Centisome position: 44.94

GC content: 40.84

Gene sequence:

>999_bases
ATGAATCCACTTATTTTTAAAGAAAATCGTCCATTTGACTTAATTGCAGTTGGACGTTTATGCGTTGATTTAAATGCCAA
TGAAACACAACGTCCTATGGAAGAAACAAGAACGTTTACTAAGTATGTGGGAGGTTCTCCTGCGAACATTGCGATTGGTG
CGGCGCGTCTCGGCTTACAAACGGGATTTATCGGTAAAGTGTCCGATGATCAAATGGGCCGTTTTATTACAGGGTACTTA
AAGGACAATAAGATTAATACAGACCAGATACGTATCGATTGTACAGGTGCAGTGACAGGTCTAGCATTTACAGAAATTAA
AAGCCCTGAAGATTGTAGTATTTTAATGTACCGCGACAATGTCGCAGATTTAAACCTTGATCCAACAGAGGTATCCGAGG
ACTATATTAAACAATCAAAAGCACTCTTAATTTCAGGAACAGCTTTAGCGAAAAGTCCTTCTCGCGAGGCGGTATTTCTA
GCATTAGAATATGCGCGTAAGCATGATGTAGTTGTATTTTTTGATGTGGATTACCGCCCTTATACATGGCAGTCAGAAGC
TGAAACGGCTGTGTATTACAATCTAGCGGCTGAAAAATCTGATGTCATTATTGGAACGCGTGAAGAATTCGATATGATGG
AAAAACTATTAAACTACGAACAATCTAATGACCAAGTTACGGCTGAAAGATGGTTTTCTCATTATGCGAAAATCGTTGTA
ATTAAACACGGCGGGGATGGTTCAATCGCTTATACGAGAGACGGTCAATCTCACCGCGGCGGTATCTTTAAAACAAAGGT
GTTAAAGACGTTTGGCGCTGGCGACTCGTATGCTTCTGCGTTTATTTATGGCCTAATACAAGGGCTTGAGATTCCTCAAG
CGATGCGATTAGGTGGTGCTTCTGCTTCAATCGTTATTTCTAAACATAGTTGTTCTGATGCAATGCCAACAAGGGCAGAG
ATTTCTGCATTCATGGAAACGGCTGAGGAATTGGTATAG

Upstream 100 bases:

>100_bases
AAGAGAGCGCTTACTTATAGATAGATAAAGAGTAATGAATAGTATATTTATAAAAATATGAACCTTATCATTCATTCATA
AAGCATGGGAGGTAGTAACA

Downstream 100 bases:

>100_bases
AAACGCATGAATCAATAATAAAGTAAGGGCGTATCCTATTGGACGCTTCTACATTACATAAAAGGGAGAGAATGAATATG
ACAGTACAAACAGCACCACA

Product: carbohydrate kinase; myo-inositol catabolism protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase 1; DKG kinase 1

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQTGFIGKVSDDQMGRFITGYL
KDNKINTDQIRIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFL
ALEYARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVV
IKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLIQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAE
ISAFMETAEELV

Sequences:

>Translated_332_residues
MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQTGFIGKVSDDQMGRFITGYL
KDNKINTDQIRIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFL
ALEYARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVV
IKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLIQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAE
ISAFMETAEELV
>Mature_332_residues
MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQTGFIGKVSDDQMGRFITGYL
KDNKINTDQIRIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFL
ALEYARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVV
IKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLIQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAE
ISAFMETAEELV

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

Organism=Escherichia coli, GI1790193, Length=320, Percent_Identity=25.3125, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLC1_BACCZ (Q63B75)

Other databases:

- EMBL:   CP000001
- RefSeq:   YP_083842.1
- HSSP:   Q9TVW2
- ProteinModelPortal:   Q63B75
- SMR:   Q63B75
- STRING:   Q63B75
- EnsemblBacteria:   EBBACT00000042651
- GeneID:   3022810
- GenomeReviews:   CP000001_GR
- KEGG:   bcz:BCZK2252
- eggNOG:   COG0524
- GeneTree:   EBGT00050000001879
- HOGENOM:   HBG466006
- OMA:   RPMFWSS
- ProtClustDB:   CLSK873289
- BioCyc:   BCER288681:BCE33L2252-MONOMER
- HAMAP:   MF_01668
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.92

Molecular weight: Translated: 36730; Mature: 36730

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQ
CCCCEECCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
TGFIGKVSDDQMGRFITGYLKDNKINTDQIRIDCTGAVTGLAFTEIKSPEDCSILMYRDN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEEEECC
VADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYARKHDVVVFFDVDYRP
CCCCCCCHHHHHHHHHHCCCEEEEECCHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCC
YTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVV
CCCCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEE
IKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLIQGLEIPQAMRLGGA
EEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
SASIVISKHSCSDAMPTRAEISAFMETAEELV
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQ
CCCCEECCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
TGFIGKVSDDQMGRFITGYLKDNKINTDQIRIDCTGAVTGLAFTEIKSPEDCSILMYRDN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEEEECC
VADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYARKHDVVVFFDVDYRP
CCCCCCCHHHHHHHHHHCCCEEEEECCHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCC
YTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVV
CCCCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEE
IKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLIQGLEIPQAMRLGGA
EEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
SASIVISKHSCSDAMPTRAEISAFMETAEELV
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA