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The map label for this gene is yfiS [H]

Identifier: 52142847

GI number: 52142847

Start: 2532012

End: 2533250

Strand: Direct

Name: yfiS [H]

Synonym: BCZK2393

Alternate gene names: 52142847

Gene position: 2532012-2533250 (Clockwise)

Preceding gene: 52142849

Following gene: 52142846

Centisome position: 47.77

GC content: 32.36

Gene sequence:

>1239_bases
ATGAAAAACTTACTTAAAGGTTGGAAATATCCTTTATTACTACTGTCCGGAGTTGGTATTGCAAATTTAGGGGCATGGAT
TTACTTAATAGCACTGAATGTACTTGTCTATCATATGGGTGGCTCAGCCTTAGCTGTTGCTACTTTATACGTAATTAAAC
CATTAGCTACTCTATTTACAAACGCTTGGTCAGGAAGTATGATTGATCGTTTAAATAAACGGAATTTAATGATTCACCTC
GATATATATCGCGCGGTATTTATCGCTATTTTACCTTTACTTCCATCACTTTGGATGGTTTATGTATTTGTATTCTTTAT
TAGTATGGCCAATGCAATTTATGAGCCAACTGCGATGACGTATATGACGAAATTAATACCAGTTGAACAAAGACAACGTT
TCAACTCATTACGTAGTTTAATAGGATCTGGTGCTTCTGTAATTGGTCCATCGATAGCGGGAGCATTGTTAATAGCAAGT
ACACCAGAGTTTGCTATATATATGAATGCTATAGCATTTCTCTTATCAGGAGTAATTACATTGCTGCTACCTAATCTTGA
TAAAAAATCTGATAGTCATACATCAAATGACACATTATCTTTAGCTGTACTAAAAAAAGATTGGAACATCGTTTTAAATT
TTAGTAAAAAATCTTTGTATATCGTTTTCGTGTACTTCTTATTCCAAGGGATGATGGTGTTAGCTGCCGCAAATGATTCA
CTTGAATTGTCATTTGCGAAAGAAGTTTTATTGTTAACAGATAGTGAATATGGCTTTTTAGTTAGTATTGCTGGAGCTGG
ATTTATTTTAGGAGCAATAACAAATGCAATTTTATCAAAAAAACTAACACCTTCATTGTTAATTGGTATAGGATCATTAT
TCATCGCAATCGGTTATATCATTTATGCTTTTTCAAATGAGTTTTTAATAGCTGCTATCGGATTTTTTATTTTATCTTTC
TCTATGGCATATGCAAATACAGGGTTTAATACCTTTTATCAAAATAATGTCCCTGTCCATATAATGGGACGGATTGGGAG
CATATATGGATTATTTATTGCAGGTATCACCATTTTAATTACGATTTTGTTCGGAGTTGCCACTCAATTTATTTCTATAC
AACTTGTGGTTATTATAGGTTCTTTAGTAATGTTATTTATTACTATCATCTTGTGTGTGTTTACTTTATTGCCATCACAT
TCTAAAGTGCATTCTTCTGAATCAATACATTCGAAATAA

Upstream 100 bases:

>100_bases
AGGGTGGCACCGCGATGATAAATCTCGTCCCTAAGACTAAAAGTCTTGGGGGTGGGATTTTTTTATTGGTTTAAAATAAT
TTGGAAAGCGGGGGCCTAAA

Downstream 100 bases:

>100_bases
TTCTCTTAGTTTTGATTTAAATCTTACGATGTTCAATAGGAGGGTTATCCCTCCTATATATGGAAATATAAGAAAGGAGA
ACAATATTGATAAACGAGGG

Product: permease; macrolide-efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKNLLKGWKYPLLLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLATLFTNAWSGSMIDRLNKRNLMIHL
DIYRAVFIAILPLLPSLWMVYVFVFFISMANAIYEPTAMTYMTKLIPVEQRQRFNSLRSLIGSGASVIGPSIAGALLIAS
TPEFAIYMNAIAFLLSGVITLLLPNLDKKSDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDS
LELSFAKEVLLLTDSEYGFLVSIAGAGFILGAITNAILSKKLTPSLLIGIGSLFIAIGYIIYAFSNEFLIAAIGFFILSF
SMAYANTGFNTFYQNNVPVHIMGRIGSIYGLFIAGITILITILFGVATQFISIQLVVIIGSLVMLFITIILCVFTLLPSH
SKVHSSESIHSK

Sequences:

>Translated_412_residues
MKNLLKGWKYPLLLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLATLFTNAWSGSMIDRLNKRNLMIHL
DIYRAVFIAILPLLPSLWMVYVFVFFISMANAIYEPTAMTYMTKLIPVEQRQRFNSLRSLIGSGASVIGPSIAGALLIAS
TPEFAIYMNAIAFLLSGVITLLLPNLDKKSDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDS
LELSFAKEVLLLTDSEYGFLVSIAGAGFILGAITNAILSKKLTPSLLIGIGSLFIAIGYIIYAFSNEFLIAAIGFFILSF
SMAYANTGFNTFYQNNVPVHIMGRIGSIYGLFIAGITILITILFGVATQFISIQLVVIIGSLVMLFITIILCVFTLLPSH
SKVHSSESIHSK
>Mature_412_residues
MKNLLKGWKYPLLLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLATLFTNAWSGSMIDRLNKRNLMIHL
DIYRAVFIAILPLLPSLWMVYVFVFFISMANAIYEPTAMTYMTKLIPVEQRQRFNSLRSLIGSGASVIGPSIAGALLIAS
TPEFAIYMNAIAFLLSGVITLLLPNLDKKSDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDS
LELSFAKEVLLLTDSEYGFLVSIAGAGFILGAITNAILSKKLTPSLLIGIGSLFIAIGYIIYAFSNEFLIAAIGFFILSF
SMAYANTGFNTFYQNNVPVHIMGRIGSIYGLFIAGITILITILFGVATQFISIQLVVIIGSLVMLFITIILCVFTLLPSH
SKVHSSESIHSK

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45096; Mature: 45096

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLLKGWKYPLLLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLATLFT
CCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NAWSGSMIDRLNKRNLMIHLDIYRAVFIAILPLLPSLWMVYVFVFFISMANAIYEPTAMT
CCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YMTKLIPVEQRQRFNSLRSLIGSGASVIGPSIAGALLIASTPEFAIYMNAIAFLLSGVIT
HHHHHCCHHHHHHHHHHHHHHCCCCHHCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
LLLPNLDKKSDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDS
HHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEECCCC
LELSFAKEVLLLTDSEYGFLVSIAGAGFILGAITNAILSKKLTPSLLIGIGSLFIAIGYI
EEHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IYAFSNEFLIAAIGFFILSFSMAYANTGFNTFYQNNVPVHIMGRIGSIYGLFIAGITILI
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHH
TILFGVATQFISIQLVVIIGSLVMLFITIILCVFTLLPSHSKVHSSESIHSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MKNLLKGWKYPLLLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLATLFT
CCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NAWSGSMIDRLNKRNLMIHLDIYRAVFIAILPLLPSLWMVYVFVFFISMANAIYEPTAMT
CCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YMTKLIPVEQRQRFNSLRSLIGSGASVIGPSIAGALLIASTPEFAIYMNAIAFLLSGVIT
HHHHHCCHHHHHHHHHHHHHHCCCCHHCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
LLLPNLDKKSDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDS
HHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEECCCC
LELSFAKEVLLLTDSEYGFLVSIAGAGFILGAITNAILSKKLTPSLLIGIGSLFIAIGYI
EEHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IYAFSNEFLIAAIGFFILSFSMAYANTGFNTFYQNNVPVHIMGRIGSIYGLFIAGITILI
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHH
TILFGVATQFISIQLVVIIGSLVMLFITIILCVFTLLPSHSKVHSSESIHSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]