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The map label for this gene is frr [H]

Identifier: 52141664

GI number: 52141664

Start: 3720289

End: 3720846

Strand: Reverse

Name: frr [H]

Synonym: BCZK3583

Alternate gene names: 52141664

Gene position: 3720846-3720289 (Counterclockwise)

Preceding gene: 52141663

Following gene: 52141665

Centisome position: 70.19

GC content: 36.56

Gene sequence:

>558_bases
ATGGGACAACAAGTATTAAAGTCTTCAAATGAAAAAATGGAAAAAGCAGTTGCTGCTTATTCTCGTGAATTAGCAACAGT
TCGTGCTGGCCGTGCAAGCGCGTCTGTATTAGATAAAGTACAAGTTGATTACTATGGTGCACCAACACCAGTTGTGCAAT
TAGCGAACATTACAGTTCCAGAAGCACGTTTACTTGTAATTCAACCTTATGACAAAACTTCTATCGGTGATATCGAAAAA
GCAATTTTAAAAGCAGATTTAGGCTTAAACCCTTCTAATGACGGAACTGTAATTCGTATTGCATTCCCTGCATTAACAGA
AGAGCGTCGTCGTGATCTTGTAAAAGTTGTGAAAAAATATGCTGAAGAAGCAAAAGTTGCTGTTCGTAACGTACGTCGTG
ACGGTAACGACGATCTTAAAAAGCTTGAAAAAGCTGGCGAGATTACAGAAGATGATTTAAGAGGATATACTGAAGATATC
CAAAAAGAAACAGATAAATATATTGCAAAAGTTGACGAAATCGCAAAAAACAAAGAAAAAGAAATCATGGAAGTGTAA

Upstream 100 bases:

>100_bases
ATGATATTCCATTAATTGTATTCTCAGTTATGGAAAAAGGTAATATTAAACGTGCCGTTTTAGGTGAAAATATCGGAACA
GTTGTAAGGGGGAAATAAAT

Downstream 100 bases:

>100_bases
TAGCGATACCTTCGCAAATATGACCCTCTTCTTAAGGGGGTCTTTTTACACTTTTAGGCATACGTCTGCTTGCTGGAGGG
TATGAATGATGTTTAAAAAC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV

Sequences:

>Translated_185_residues
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV
>Mature_184_residues
GQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKA
ILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQ
KETDKYIAKVDEIAKNKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI291042689, Length=186, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=47.8260869565217, Blast_Score=175, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=26.2857142857143, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20620; Mature: 20489

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC
>Mature Secondary Structure 
GQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA