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The map label for this gene is ilvE [H]

Identifier: 51893824

GI number: 51893824

Start: 2875887

End: 2876762

Strand: Reverse

Name: ilvE [H]

Synonym: STH2686

Alternate gene names: 51893824

Gene position: 2876762-2875887 (Counterclockwise)

Preceding gene: 51893825

Following gene: 51893823

Centisome position: 80.67

GC content: 68.04

Gene sequence:

>876_bases
GTGTCCATCCAGGTCTACGTGGACGGCGAGTGGTACTCCCGGGACGAGGCCAAGGTGTCCGTGTTTGACCACGGCTTCCT
GTACGGCGACGGCGTCTTCGAGGGCATCCGGGCCTACGGCGGGCGGGTCTTCCGGCTGACCGAGCACCTGGACCGGCTGT
ACGACTCCGCCAGGGCGATCTGGCTGGAGATCCCGCTGTCGTGGCGGGAGATGGAGGGGGTCGTGCTGGAGACGCTGCGC
CGCTCGAACCTGCGCGATGCCTACATCCGGCTGGTGGTGTCCCGGGGCCGGGGCGACCTGGGGCTGGATCCCCGCAAGTG
CCCCCGGCCGACGGTGGTCTGCATCGCCGACTCCATCGCCCTCTACCCGGAGGAGGTCTACACCCGGGGGATGCAGGTGA
TCTCCGTCTCCACCCGGCGGAACCCGCCGGATACGGTCTGGCCGCAGGTGAAGAGCCTCAACTACCTGACCAGCATCATC
GCCAAGATCAGCGCCGCCACCCAGGGGTATCCCGAGGTCATCATGCTGAACAAGGAAGGCTACGTCTGCGAGGGCACCGG
CGACAACATCTTCATCGTGAAGAAGGGCCGGCTGATCACCCCGGCGGTCCATCTGGGCATCCTGCCCGGCATCACCCGGG
CGGCGGTGATGGAGTACGCCCGGGACCTGGGCTACGCGGTGGAGGAGGGCACCTTCACCCTATACGACCTGTACACCGCG
GACGAGTGCTTCCTCACGGGCACCGCGGCGGAGATCGTGCCGGTGGTGGAGTGCGATGCCCGGAAGATCGGCTCGGGCCA
GCCCGGCGAGATCACCAGGCAGCTCATCGCCGAGTTCCGCCGGCGGGTGCAGGTCGAAGGCACGCCGATCGGCTGA

Upstream 100 bases:

>100_bases
GATGAACAAGATCCTCTCCGGGGCCGCGCTGGCCGTGTCGGACGATCCGGCGCCGGGCTGGCAGATGCGGGCCTACGGGG
ACTGAGGGGGGGCGTTGGCG

Downstream 100 bases:

>100_bases
CCAAAGTCCACGCAAGCGACGATGGAGGGATCGACGGTGCGCAGCGACCTGATCAAGAAGGGGCCCGACCGGGCCCCGCA
TCGAGCGCTGCTGAAGGCGA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSIQVYVDGEWYSRDEAKVSVFDHGFLYGDGVFEGIRAYGGRVFRLTEHLDRLYDSARAIWLEIPLSWREMEGVVLETLR
RSNLRDAYIRLVVSRGRGDLGLDPRKCPRPTVVCIADSIALYPEEVYTRGMQVISVSTRRNPPDTVWPQVKSLNYLTSII
AKISAATQGYPEVIMLNKEGYVCEGTGDNIFIVKKGRLITPAVHLGILPGITRAAVMEYARDLGYAVEEGTFTLYDLYTA
DECFLTGTAAEIVPVVECDARKIGSGQPGEITRQLIAEFRRRVQVEGTPIG

Sequences:

>Translated_291_residues
MSIQVYVDGEWYSRDEAKVSVFDHGFLYGDGVFEGIRAYGGRVFRLTEHLDRLYDSARAIWLEIPLSWREMEGVVLETLR
RSNLRDAYIRLVVSRGRGDLGLDPRKCPRPTVVCIADSIALYPEEVYTRGMQVISVSTRRNPPDTVWPQVKSLNYLTSII
AKISAATQGYPEVIMLNKEGYVCEGTGDNIFIVKKGRLITPAVHLGILPGITRAAVMEYARDLGYAVEEGTFTLYDLYTA
DECFLTGTAAEIVPVVECDARKIGSGQPGEITRQLIAEFRRRVQVEGTPIG
>Mature_290_residues
SIQVYVDGEWYSRDEAKVSVFDHGFLYGDGVFEGIRAYGGRVFRLTEHLDRLYDSARAIWLEIPLSWREMEGVVLETLRR
SNLRDAYIRLVVSRGRGDLGLDPRKCPRPTVVCIADSIALYPEEVYTRGMQVISVSTRRNPPDTVWPQVKSLNYLTSIIA
KISAATQGYPEVIMLNKEGYVCEGTGDNIFIVKKGRLITPAVHLGILPGITRAAVMEYARDLGYAVEEGTFTLYDLYTAD
ECFLTGTAAEIVPVVECDARKIGSGQPGEITRQLIAEFRRRVQVEGTPIG

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=281, Percent_Identity=37.0106761565836, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787338, Length=245, Percent_Identity=23.265306122449, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32549; Mature: 32418

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQVYVDGEWYSRDEAKVSVFDHGFLYGDGVFEGIRAYGGRVFRLTEHLDRLYDSARAI
CEEEEEECCCEECCCCCEEEEEECCEEECCHHHHHHHHHCCEEEEHHHHHHHHHHCCEEE
WLEIPLSWREMEGVVLETLRRSNLRDAYIRLVVSRGRGDLGLDPRKCPRPTVVCIADSIA
EEEECCCHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCHH
LYPEEVYTRGMQVISVSTRRNPPDTVWPQVKSLNYLTSIIAKISAATQGYPEVIMLNKEG
CCCHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
YVCEGTGDNIFIVKKGRLITPAVHLGILPGITRAAVMEYARDLGYAVEEGTFTLYDLYTA
EEEECCCCEEEEEECCCEECHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEEEEEEC
DECFLTGTAAEIVPVVECDARKIGSGQPGEITRQLIAEFRRRVQVEGTPIG
CCEEEECCHHHEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure 
SIQVYVDGEWYSRDEAKVSVFDHGFLYGDGVFEGIRAYGGRVFRLTEHLDRLYDSARAI
EEEEEECCCEECCCCCEEEEEECCEEECCHHHHHHHHHCCEEEEHHHHHHHHHHCCEEE
WLEIPLSWREMEGVVLETLRRSNLRDAYIRLVVSRGRGDLGLDPRKCPRPTVVCIADSIA
EEEECCCHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCHH
LYPEEVYTRGMQVISVSTRRNPPDTVWPQVKSLNYLTSIIAKISAATQGYPEVIMLNKEG
CCCHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
YVCEGTGDNIFIVKKGRLITPAVHLGILPGITRAAVMEYARDLGYAVEEGTFTLYDLYTA
EEEECCCCEEEEEECCCEECHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEEEEEEC
DECFLTGTAAEIVPVVECDARKIGSGQPGEITRQLIAEFRRRVQVEGTPIG
CCEEEECCHHHEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]