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The map label for this gene is kefA [C]

Identifier: 51893764

GI number: 51893764

Start: 2819210

End: 2820343

Strand: Reverse

Name: kefA [C]

Synonym: STH2626

Alternate gene names: 51893764

Gene position: 2820343-2819210 (Counterclockwise)

Preceding gene: 51893765

Following gene: 51893763

Centisome position: 79.09

GC content: 67.46

Gene sequence:

>1134_bases
ATGGCCTGGGCCGTCTTCGCGGCGCAACTGCTGGTGACCTGGGCCGTGGCCGGGCTGGCCAAGCGGATCCTGCGGTGGAT
CGCCCACCGCGTGGTCAGCCGGTCCGACACCACCCTGGACGACCGGTTGGTGGAGGCCGGCACCCCGGCGGTGCGGTGGG
TCATCCTCGCCCTGGGCCTGCGGCTCGCCCTGATGTCGCTGGGCAGCGCCATCCCCTCCTTCCAGGCCGGGGGACGGTAT
GCGACCCAGTTCACCGTGGCCGGCAACCTGGCCGAGGCGGTGGTGGTGATCGCGGTCACCGTCCTGGTCAACGCCCTGAT
CAACGCCGCGCTGGACTGGTATCTGCACGAGCTGGCCGGCCGGACCGACGGCACGTGGGACCGGGAGCTCATGCCGATGA
TCAAGAAGGGCGTGTCCGCGGTGGTCGGCTTTTTCGCGCTGTCCATCGTGCTGGAGCTGTTCGGGATCTCGGTGTCCGCC
CTGATCGCCACGGCCGGCGTCGCCTCCGCGGCGATCGCCCTCGCGTCCCAGGACACGCTCTCCAACATGCTGGGCGGGCT
GGCCATCCTCATCGACCGGCCGTTCCGGGTGGGCGACTGGATCGAGCTGACCGACGGCAAGGTGGGCGTGGTGGTGGAGA
TCGGGCTGCGCACCACCCGCATCCGGCAGTTTGACGGCACCGCCCTCGTGGTGCCCAACAAGGACATGGCCAACACCCGG
GTGATCAACTACGCGCTGCCCTCGCCCCAGGCCGCGATCCGGCAGACCATCCGGGTGACCTACGACACCGATGTGGAGAA
GGCGAAGAAGGTGCTGCTGGACGTGCTCCAGAGCCATCCCGAGGTGCTGAAGGACCCGGTTCCCGGGGTGTGGCTCTCCG
CCTTCAACACCTACTCCCTGGACCTCTTCTTCAGCTGCTGGGTCGACTCGTACACCAACCGGTTCCGGGTGACCGATGAG
CTGAACATGCAGATCCTGAAGGCCTTCCGGGAAAACGGCATCGCGCTGGCGATTCCTGCGCAACATATCCGCATCCAGCA
GAAGGAGGATTCCCTTGACCAGGCAGTGGAGCTCCCCGCCCCCGATGGAAATCGACCCGTCCAAGCGGTACCGGGCGACC
CTGAGAACCACTAA

Upstream 100 bases:

>100_bases
CGGGCTGAACTTCTATTATGTAAAGGATGACGTTCTGCACGGGGGAATGGTAGTGGAACAGTGGCTGTACGACCTGCGGA
CTGCGCTGGAGCAACACTGG

Downstream 100 bases:

>100_bases
GGGTGAGATCGTCATCGACCTGTTCGCGGACGAGGCCCCGCTCGCCGTCAACAACTTCGTCTTCCTGGCGCGCCAGGGGT
ATTACGACGGGGTGAAGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MAWAVFAAQLLVTWAVAGLAKRILRWIAHRVVSRSDTTLDDRLVEAGTPAVRWVILALGLRLALMSLGSAIPSFQAGGRY
ATQFTVAGNLAEAVVVIAVTVLVNALINAALDWYLHELAGRTDGTWDRELMPMIKKGVSAVVGFFALSIVLELFGISVSA
LIATAGVASAAIALASQDTLSNMLGGLAILIDRPFRVGDWIELTDGKVGVVVEIGLRTTRIRQFDGTALVVPNKDMANTR
VINYALPSPQAAIRQTIRVTYDTDVEKAKKVLLDVLQSHPEVLKDPVPGVWLSAFNTYSLDLFFSCWVDSYTNRFRVTDE
LNMQILKAFRENGIALAIPAQHIRIQQKEDSLDQAVELPAPDGNRPVQAVPGDPENH

Sequences:

>Translated_377_residues
MAWAVFAAQLLVTWAVAGLAKRILRWIAHRVVSRSDTTLDDRLVEAGTPAVRWVILALGLRLALMSLGSAIPSFQAGGRY
ATQFTVAGNLAEAVVVIAVTVLVNALINAALDWYLHELAGRTDGTWDRELMPMIKKGVSAVVGFFALSIVLELFGISVSA
LIATAGVASAAIALASQDTLSNMLGGLAILIDRPFRVGDWIELTDGKVGVVVEIGLRTTRIRQFDGTALVVPNKDMANTR
VINYALPSPQAAIRQTIRVTYDTDVEKAKKVLLDVLQSHPEVLKDPVPGVWLSAFNTYSLDLFFSCWVDSYTNRFRVTDE
LNMQILKAFRENGIALAIPAQHIRIQQKEDSLDQAVELPAPDGNRPVQAVPGDPENH
>Mature_376_residues
AWAVFAAQLLVTWAVAGLAKRILRWIAHRVVSRSDTTLDDRLVEAGTPAVRWVILALGLRLALMSLGSAIPSFQAGGRYA
TQFTVAGNLAEAVVVIAVTVLVNALINAALDWYLHELAGRTDGTWDRELMPMIKKGVSAVVGFFALSIVLELFGISVSAL
IATAGVASAAIALASQDTLSNMLGGLAILIDRPFRVGDWIELTDGKVGVVVEIGLRTTRIRQFDGTALVVPNKDMANTRV
INYALPSPQAAIRQTIRVTYDTDVEKAKKVLLDVLQSHPEVLKDPVPGVWLSAFNTYSLDLFFSCWVDSYTNRFRVTDEL
NMQILKAFRENGIALAIPAQHIRIQQKEDSLDQAVELPAPDGNRPVQAVPGDPENH

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=218, Percent_Identity=31.651376146789, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789291, Length=271, Percent_Identity=27.6752767527675, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787591, Length=199, Percent_Identity=29.6482412060301, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367355, Length=209, Percent_Identity=24.8803827751196, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 41001; Mature: 40870

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWAVFAAQLLVTWAVAGLAKRILRWIAHRVVSRSDTTLDDRLVEAGTPAVRWVILALGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHH
RLALMSLGSAIPSFQAGGRYATQFTVAGNLAEAVVVIAVTVLVNALINAALDWYLHELAG
HHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RTDGTWDRELMPMIKKGVSAVVGFFALSIVLELFGISVSALIATAGVASAAIALASQDTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SNMLGGLAILIDRPFRVGDWIELTDGKVGVVVEIGLRTTRIRQFDGTALVVPNKDMANTR
HHHHCCEEEEEECCCCCCCEEEECCCCEEEEEEECCCEEEEEEECCCEEEECCCCCCCCE
VINYALPSPQAAIRQTIRVTYDTDVEKAKKVLLDVLQSHPEVLKDPVPGVWLSAFNTYSL
EEEEECCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCHHH
DLFFSCWVDSYTNRFRVTDELNMQILKAFRENGIALAIPAQHIRIQQKEDSLDQAVELPA
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHCCCEEEECHHHHEEECHHCCHHHHEECCC
PDGNRPVQAVPGDPENH
CCCCCCEEECCCCCCCC
>Mature Secondary Structure 
AWAVFAAQLLVTWAVAGLAKRILRWIAHRVVSRSDTTLDDRLVEAGTPAVRWVILALGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHH
RLALMSLGSAIPSFQAGGRYATQFTVAGNLAEAVVVIAVTVLVNALINAALDWYLHELAG
HHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RTDGTWDRELMPMIKKGVSAVVGFFALSIVLELFGISVSALIATAGVASAAIALASQDTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SNMLGGLAILIDRPFRVGDWIELTDGKVGVVVEIGLRTTRIRQFDGTALVVPNKDMANTR
HHHHCCEEEEEECCCCCCCEEEECCCCEEEEEEECCCEEEEEEECCCEEEECCCCCCCCE
VINYALPSPQAAIRQTIRVTYDTDVEKAKKVLLDVLQSHPEVLKDPVPGVWLSAFNTYSL
EEEEECCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCHHH
DLFFSCWVDSYTNRFRVTDELNMQILKAFRENGIALAIPAQHIRIQQKEDSLDQAVELPA
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHCCCEEEECHHHHEEECHHCCHHHHEECCC
PDGNRPVQAVPGDPENH
CCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]