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The map label for this gene is nagA [H]

Identifier: 50841967

GI number: 50841967

Start: 534270

End: 535400

Strand: Direct

Name: nagA [H]

Synonym: PPA0484

Alternate gene names: 50841967

Gene position: 534270-535400 (Clockwise)

Preceding gene: 50841965

Following gene: 50841968

Centisome position: 20.87

GC content: 61.45

Gene sequence:

>1131_bases
ATGATCACCCGCATTGCTTCTCACCACGTCGTCGATCGCGATGGTAGTGATTCACCAGCGACGATCACCGTCGAGGCTGG
ACGCATTAGTGACGTCAGCGAGGGTATTGATCCCAAGGCCGAACTCGTTGATGAGTGGATTTTGCCCGGATATGTCGACA
CTCACTGTCACGGTGGCGCCGGTGCTGACTTCACCGACCCTGACCGCGAGGCCGCTTTGCGCGCCGTCCATTACCACCGC
AGCCAGGGGTCGACGACTCTTTTCGCATCGACGGTGACCGCAGCGATTGACGACGTCGTCGCGCAGATTGGGCGACTCCG
CCAGCTTGTCGACCTTGACGAGATCGCCGGCATCCATTTAGAGGGGCCGTTCTTGGCTGAATCGCGGAAGGGGGCCCACG
CCGTCGAGCTGCTGTGTGACCCAGATCCGGTGTCCGTGGGTCGTCTCATCGAAGCTGGCGGTTCGGCTCTCAAGATGGTG
ACTATTGCGCCAGAACGTGCGCACGGCTTGGAAGCGGTGACCACCTTCACCACAGCCGGAGTGCACGCTGCTATCGGCCA
TACTGAGTGTGACACCACCACGGCTAGTGCCGCAGTCGACGCGGGAGCAGACGTCATCACCCATCTGTTCAACGCGATGC
CGTCGATCCATCATCGAAAGCCCGGTCCGGTGCCGCCAATGCTCACTGATTCGCGAGTGGTCTGCGAACTCATTTGCGAC
GGCGTCCACTTGGCCCCGGACGTCATTCGGATGGCGATGTCGAGCGCCGGCCCGAAGCGCATCGCCCTGGTGACCGATGC
CATGAGCGCGACCGGTCAGCCTGACGGCGACTACATTCTGGGCAGCCTGCCAGTGAAAGTTGTGGATGGAAGAGCCCGTT
TGTTGGCCGCTGACGGTTCGCTGGGAGCGATAGCAGGATCGACTCTGACGATGGGTCGAGCGGTCGAATTCGTCACGTCC
GTTGTGGGTATCCCGCTGGGACAGGTCGCCGTCATGGCGGCCACAACACCGGCCAAGCTCCATGGTTTGAACGAGGTTGG
CGTCATCGAAGAGGGCCACTGGGCTGACTTGTGTCTTACTGACGCGAAGGGTCATCTGGTGCGCGTCATTCACCGGGGTG
AGGCTGTCTGA

Upstream 100 bases:

>100_bases
TGAGCCATAATCCGATCCTTGCAGATCATGTCGTCTATAACGGCGGAGTTCATGCTGTGATCGTGTGGCAAGATGAGGGA
AACCCGGTTAGGAGGCATCG

Downstream 100 bases:

>100_bases
CGGCCAGAGCGGGTGATTGGGCACTAAACTTTTCATGGAGAGGGTCGCTCGGGCGTAAGCAATGGCGCCCGAAAGATTGT
TGACAGTTAGCTTGTCCAGT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MITRIASHHVVDRDGSDSPATITVEAGRISDVSEGIDPKAELVDEWILPGYVDTHCHGGAGADFTDPDREAALRAVHYHR
SQGSTTLFASTVTAAIDDVVAQIGRLRQLVDLDEIAGIHLEGPFLAESRKGAHAVELLCDPDPVSVGRLIEAGGSALKMV
TIAPERAHGLEAVTTFTTAGVHAAIGHTECDTTTASAAVDAGADVITHLFNAMPSIHHRKPGPVPPMLTDSRVVCELICD
GVHLAPDVIRMAMSSAGPKRIALVTDAMSATGQPDGDYILGSLPVKVVDGRARLLAADGSLGAIAGSTLTMGRAVEFVTS
VVGIPLGQVAVMAATTPAKLHGLNEVGVIEEGHWADLCLTDAKGHLVRVIHRGEAV

Sequences:

>Translated_376_residues
MITRIASHHVVDRDGSDSPATITVEAGRISDVSEGIDPKAELVDEWILPGYVDTHCHGGAGADFTDPDREAALRAVHYHR
SQGSTTLFASTVTAAIDDVVAQIGRLRQLVDLDEIAGIHLEGPFLAESRKGAHAVELLCDPDPVSVGRLIEAGGSALKMV
TIAPERAHGLEAVTTFTTAGVHAAIGHTECDTTTASAAVDAGADVITHLFNAMPSIHHRKPGPVPPMLTDSRVVCELICD
GVHLAPDVIRMAMSSAGPKRIALVTDAMSATGQPDGDYILGSLPVKVVDGRARLLAADGSLGAIAGSTLTMGRAVEFVTS
VVGIPLGQVAVMAATTPAKLHGLNEVGVIEEGHWADLCLTDAKGHLVRVIHRGEAV
>Mature_376_residues
MITRIASHHVVDRDGSDSPATITVEAGRISDVSEGIDPKAELVDEWILPGYVDTHCHGGAGADFTDPDREAALRAVHYHR
SQGSTTLFASTVTAAIDDVVAQIGRLRQLVDLDEIAGIHLEGPFLAESRKGAHAVELLCDPDPVSVGRLIEAGGSALKMV
TIAPERAHGLEAVTTFTTAGVHAAIGHTECDTTTASAAVDAGADVITHLFNAMPSIHHRKPGPVPPMLTDSRVVCELICD
GVHLAPDVIRMAMSSAGPKRIALVTDAMSATGQPDGDYILGSLPVKVVDGRARLLAADGSLGAIAGSTLTMGRAVEFVTS
VVGIPLGQVAVMAATTPAKLHGLNEVGVIEEGHWADLCLTDAKGHLVRVIHRGEAV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=405, Percent_Identity=29.1358024691358, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI224922791, Length=395, Percent_Identity=29.1139240506329, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786892, Length=336, Percent_Identity=29.1666666666667, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17553768, Length=383, Percent_Identity=30.8093994778068, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19920392, Length=327, Percent_Identity=32.1100917431193, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281361140, Length=340, Percent_Identity=30.8823529411765, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39124; Mature: 39124

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRIASHHVVDRDGSDSPATITVEAGRISDVSEGIDPKAELVDEWILPGYVDTHCHGGA
CCCCCCCCCEECCCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
GADFTDPDREAALRAVHYHRSQGSTTLFASTVTAAIDDVVAQIGRLRQLVDLDEIAGIHL
CCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEE
EGPFLAESRKGAHAVELLCDPDPVSVGRLIEAGGSALKMVTIAPERAHGLEAVTTFTTAG
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCHHCCCHHHHHHHHCC
VHAAIGHTECDTTTASAAVDAGADVITHLFNAMPSIHHRKPGPVPPMLTDSRVVCELICD
CEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHC
GVHLAPDVIRMAMSSAGPKRIALVTDAMSATGQPDGDYILGSLPVKVVDGRARLLAADGS
CCCCCHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCEEEECCCEEEECCCEEEEEECCC
LGAIAGSTLTMGRAVEFVTSVVGIPLGQVAVMAATTPAKLHGLNEVGVIEEGHWADLCLT
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCEECCCCEEEEEE
DAKGHLVRVIHRGEAV
CCCCCEEEEEECCCCC
>Mature Secondary Structure
MITRIASHHVVDRDGSDSPATITVEAGRISDVSEGIDPKAELVDEWILPGYVDTHCHGGA
CCCCCCCCCEECCCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
GADFTDPDREAALRAVHYHRSQGSTTLFASTVTAAIDDVVAQIGRLRQLVDLDEIAGIHL
CCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEE
EGPFLAESRKGAHAVELLCDPDPVSVGRLIEAGGSALKMVTIAPERAHGLEAVTTFTTAG
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCHHCCCHHHHHHHHCC
VHAAIGHTECDTTTASAAVDAGADVITHLFNAMPSIHHRKPGPVPPMLTDSRVVCELICD
CEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHC
GVHLAPDVIRMAMSSAGPKRIALVTDAMSATGQPDGDYILGSLPVKVVDGRARLLAADGS
CCCCCHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCCEEEECCCEEEECCCEEEEEECCC
LGAIAGSTLTMGRAVEFVTSVVGIPLGQVAVMAATTPAKLHGLNEVGVIEEGHWADLCLT
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCEECCCCEEEEEE
DAKGHLVRVIHRGEAV
CCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA