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The map label for this gene is disA [H]

Identifier: 229259642

GI number: 229259642

Start: 362009

End: 363055

Strand: Reverse

Name: disA [H]

Synonym: PPA0311

Alternate gene names: 229259642

Gene position: 363055-362009 (Counterclockwise)

Preceding gene: 50841799

Following gene: 50841794

Centisome position: 14.18

GC content: 59.6

Gene sequence:

>1047_bases
GTGCGCCATCTAATGGCCCTCTTGGCCCCTGGCACGCCCATCCGGGAAGGACTAGATCGCATCGTTAACGGACGCACTGG
TGGTCTCATCGTGCTCGGTGATGGGCCAGAGATCAACGGGGTTTGTTCCGGCGGATTCCCCCTTGACGTCAGACTCACCC
CGCAGGCTCTGCGCGAGCTATCCAAGATGGACGGTGGGCTAGTGGTCTCGAGTGATCACGAGCGCATCAAAGCAGCTGCG
GTCCACTTCGTCCCCGACGGTAGCCTGCCCACGTTGGAGACTGGTACCCGTCACCGCACGGCAGATCGGCTCTCCCAACA
AACCGGTGTGCCGGTGGTAGTCGTCTCGGCGTCGATGTCAGTGATGTCGCTCTTCCTTAACGGCCGTCGGTACCTGATCG
AGAGGCCTGAACAGTTGCTCGCTCGAGCCAATCAGGCCCTTGCCACCCTGGCAAGCTACCGCGGGCGTCTGGTCGACGAG
GCCGAGAACCTCACCACCTTAGAGATTCGCGACCAAGTCCAGGTGCGTGACGTCGCCGCTGTCGCCCAGCGGGTCGAAAT
GTGGCGTCGTATCGATGCCGAGGTCCGTGGATATGTCTCTGCTCTGGGTGTGGAGGGACGCCTTGTCCAATTACAACGCA
ACGAACTGTCCCTAGGCGTAGAAGACCTAGGCCGGTTGCTCACTGATGACTATCGTCCCAATTCCGTCGCTCCTGGCGGG
TTTTCCCTGTCAGGATTACAGAAACTGTCCTGGGAAGATCTGCTCAATGTGACCATGGTGGCCGAGACCATCAACCTCGG
TCCTGCTGAACACCCGCTGGATTCCCCCATTCGGGCACGCGGTCATCGACAGCTGACACTCATGACGGACCTGTCGTCAC
GCACAATCCAGCGGATTATTGACCACTTCAGCGATCTGCAAAGCCTGGTGTCAGCATCCACCTCCGAGCTCGGCGATATT
AAGGGGGTCGGCCTCAGACGGGCCCGTGAAATTCGCCAAGGGTTAGAGTCGATCTTTGAAGGCGATCAGCGCACCCATCA
TCATTAG

Upstream 100 bases:

>100_bases
GGACATCTGAGGTGAGAACCGCGGCACAGCGAACTAGAGTCGACTCATGAACGACGTCCAGCCCGATCCCGAGACGTCCC
GGGAGATGCAGGCGGAACAG

Downstream 100 bases:

>100_bases
ATCCGCATATGCATTGACACGTGTGTCGACAGGGTTCAGGTACCCATCCGCATAACGAAGCGGCCGCTAGGGCCGCCACC
GAGATTTACAGTGGCGACAT

Product: DNA integrity scanning protein DisA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRHLMALLAPGTPIREGLDRIVNGRTGGLIVLGDGPEINGVCSGGFPLDVRLTPQALRELSKMDGGLVVSSDHERIKAAA
VHFVPDGSLPTLETGTRHRTADRLSQQTGVPVVVVSASMSVMSLFLNGRRYLIERPEQLLARANQALATLASYRGRLVDE
AENLTTLEIRDQVQVRDVAAVAQRVEMWRRIDAEVRGYVSALGVEGRLVQLQRNELSLGVEDLGRLLTDDYRPNSVAPGG
FSLSGLQKLSWEDLLNVTMVAETINLGPAEHPLDSPIRARGHRQLTLMTDLSSRTIQRIIDHFSDLQSLVSASTSELGDI
KGVGLRRAREIRQGLESIFEGDQRTHHH

Sequences:

>Translated_348_residues
MRHLMALLAPGTPIREGLDRIVNGRTGGLIVLGDGPEINGVCSGGFPLDVRLTPQALRELSKMDGGLVVSSDHERIKAAA
VHFVPDGSLPTLETGTRHRTADRLSQQTGVPVVVVSASMSVMSLFLNGRRYLIERPEQLLARANQALATLASYRGRLVDE
AENLTTLEIRDQVQVRDVAAVAQRVEMWRRIDAEVRGYVSALGVEGRLVQLQRNELSLGVEDLGRLLTDDYRPNSVAPGG
FSLSGLQKLSWEDLLNVTMVAETINLGPAEHPLDSPIRARGHRQLTLMTDLSSRTIQRIIDHFSDLQSLVSASTSELGDI
KGVGLRRAREIRQGLESIFEGDQRTHHH
>Mature_348_residues
MRHLMALLAPGTPIREGLDRIVNGRTGGLIVLGDGPEINGVCSGGFPLDVRLTPQALRELSKMDGGLVVSSDHERIKAAA
VHFVPDGSLPTLETGTRHRTADRLSQQTGVPVVVVSASMSVMSLFLNGRRYLIERPEQLLARANQALATLASYRGRLVDE
AENLTTLEIRDQVQVRDVAAVAQRVEMWRRIDAEVRGYVSALGVEGRLVQLQRNELSLGVEDLGRLLTDDYRPNSVAPGG
FSLSGLQKLSWEDLLNVTMVAETINLGPAEHPLDSPIRARGHRQLTLMTDLSSRTIQRIIDHFSDLQSLVSASTSELGDI
KGVGLRRAREIRQGLESIFEGDQRTHHH

Specific function: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions [H]

COG id: COG1623

COG function: function code R; Predicted nucleic-acid-binding protein (contains the HHH domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the disA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018906
- InterPro:   IPR003390
- InterPro:   IPR010994 [H]

Pfam domain/function: PF10635 DisA-linker; PF02457 DisA_N [H]

EC number: NA

Molecular weight: Translated: 38171; Mature: 38171

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLMALLAPGTPIREGLDRIVNGRTGGLIVLGDGPEINGVCSGGFPLDVRLTPQALREL
CCHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCEEEEEECHHHHHHH
SKMDGGLVVSSDHERIKAAAVHFVPDGSLPTLETGTRHRTADRLSQQTGVPVVVVSASMS
HHCCCCEEEECCHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
VMSLFLNGRRYLIERPEQLLARANQALATLASYRGRLVDEAENLTTLEIRDQVQVRDVAA
HHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCHHHHHHHHH
VAQRVEMWRRIDAEVRGYVSALGVEGRLVQLQRNELSLGVEDLGRLLTDDYRPNSVAPGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCC
FSLSGLQKLSWEDLLNVTMVAETINLGPAEHPLDSPIRARGHRQLTLMTDLSSRTIQRII
CCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEECHHHHHHHHHH
DHFSDLQSLVSASTSELGDIKGVGLRRAREIRQGLESIFEGDQRTHHH
HHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRHLMALLAPGTPIREGLDRIVNGRTGGLIVLGDGPEINGVCSGGFPLDVRLTPQALREL
CCHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCEEEEEECHHHHHHH
SKMDGGLVVSSDHERIKAAAVHFVPDGSLPTLETGTRHRTADRLSQQTGVPVVVVSASMS
HHCCCCEEEECCHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
VMSLFLNGRRYLIERPEQLLARANQALATLASYRGRLVDEAENLTTLEIRDQVQVRDVAA
HHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCHHHHHHHHH
VAQRVEMWRRIDAEVRGYVSALGVEGRLVQLQRNELSLGVEDLGRLLTDDYRPNSVAPGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCC
FSLSGLQKLSWEDLLNVTMVAETINLGPAEHPLDSPIRARGHRQLTLMTDLSSRTIQRII
CCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEECHHHHHHHHHH
DHFSDLQSLVSASTSELGDIKGVGLRRAREIRQGLESIFEGDQRTHHH
HHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA