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The map label for this gene is crh [H]

Identifier: 49187987

GI number: 49187987

Start: 4873894

End: 4874142

Strand: Reverse

Name: crh [H]

Synonym: BAS5001

Alternate gene names: 49187987

Gene position: 4874142-4873894 (Counterclockwise)

Preceding gene: 49187988

Following gene: 49187978

Centisome position: 93.22

GC content: 40.16

Gene sequence:

>249_bases
GTGGTTCAAAAAAGAGTTCAGGTTTCATTAAAAAACGGTTTACAAGCACGTCCGGCTGCGTTGTTTGTACAAGAGGCCAA
TCGCTTTCATGCAGATATCTTCATCGAGAAAGATGGAAAGACAGTAAATGCAAAGAGCATAATGGGGATTATGAGCTTAG
CAATTGGAACTGGTAGCATGATAACAATTACAACAGAAGGTTCAGATGCAGAAGAGGCTTTAGAGGCATTAGCTGCATAT
GTACAGTAA

Upstream 100 bases:

>100_bases
GTATTAATCATCGTTTGCGTAAAATCGATGATATTGCAGAGAAATTACGCGCGGGGGAAACGGTAGCAAAAAAATAAGAG
GTTAAAGGGGAAATGGAGCT

Downstream 100 bases:

>100_bases
GAAAGCTATCGCGTATGTGCGATAGCTTTTTGTTTTGTTATTTGCGCGGATTGGTGGGGAGGGTATGTGGAGTGTGCATG
CTTGTCGAGGATTGTCGGTA

Product: phosphocarrier protein Chr

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate; alpha,alpha-trehalose 6-phosphate [Cytoplasm]; mannitol-1-phosphate [Cytoplasm]; D-glucosamine-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; galactitol-1-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm]; fructose-1-phosphate [Cytoplasm]; glucose-6-phosphate [Cytoplasm]; mannitol-1-phosphate [Cytoplasm]; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm]; salicin-6-phosphate [Cytoplasm]; arbutin-6-phosphate [Cytoplasm] [C]

Alternate protein names: Catabolite repression HPr [H]

Number of amino acids: Translated: 82; Mature: 82

Protein sequence:

>82_residues
MVQKRVQVSLKNGLQARPAALFVQEANRFHADIFIEKDGKTVNAKSIMGIMSLAIGTGSMITITTEGSDAEEALEALAAY
VQ

Sequences:

>Translated_82_residues
MVQKRVQVSLKNGLQARPAALFVQEANRFHADIFIEKDGKTVNAKSIMGIMSLAIGTGSMITITTEGSDAEEALEALAAY
VQ
>Mature_82_residues
MVQKRVQVSLKNGLQARPAALFVQEANRFHADIFIEKDGKTVNAKSIMGIMSLAIGTGSMITITTEGSDAEEALEALAAY
VQ

Specific function: Involved in carbon catabolite repression (CCR) [H]

COG id: COG1925

COG function: function code G; Phosphotransferase system, HPr-related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPr domain [H]

Homologues:

Organism=Escherichia coli, GI1788755, Length=77, Percent_Identity=40.2597402597403, Blast_Score=69, Evalue=6e-14,

Paralogues:

None

Copy number: 4180 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 2100 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 3235 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005698
- InterPro:   IPR000032
- InterPro:   IPR002114 [H]

Pfam domain/function: PF00381 PTS-HPr [H]

EC number: NA

Molecular weight: Translated: 8796; Mature: 8796

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKRVQVSLKNGLQARPAALFVQEANRFHADIFIEKDGKTVNAKSIMGIMSLAIGTGSM
CCCCCEEEEECCCCCCCCHHEEEECCCCEEEEEEEECCCCEECHHHHHHHHHHHCCCCCE
ITITTEGSDAEEALEALAAYVQ
EEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVQKRVQVSLKNGLQARPAALFVQEANRFHADIFIEKDGKTVNAKSIMGIMSLAIGTGSM
CCCCCEEEEECCCCCCCCHHEEEECCCCEEEEEEEECCCCEECHHHHHHHHHHHCCCCCE
ITITTEGSDAEEALEALAAYVQ
EEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sorbitol [Periplasm]; phosphoenolpyruvate; trehalose [Periplasm]; mannitol [Periplasm]; glucosamine [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; galactitol [Periplasm]; fructose [Periplasm]; beta-D-glucose [Periplasm]; diacetylchitobiose [Periplasm]; cellobiose [Periplasm]; salicin [Periplasm]; arbutin [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + trehalose [Periplasm] = alpha,alpha-trehalose 6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + mannitol [Periplasm] = mannitol-1-phosp

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]