| Definition | Bacillus anthracis str. Sterne chromosome, complete genome. |
|---|---|
| Accession | NC_005945 |
| Length | 5,228,663 |
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The map label for this gene is comEC [H]
Identifier: 49187219
GI number: 49187219
Start: 4138961
End: 4141279
Strand: Reverse
Name: comEC [H]
Synonym: BAS4223
Alternate gene names: 49187219
Gene position: 4141279-4138961 (Counterclockwise)
Preceding gene: 49187220
Following gene: 49187218
Centisome position: 79.2
GC content: 36.31
Gene sequence:
>2319_bases TTGCAAGGACAATGGGGCTACGTTGCAATCTCATTTATAATAGGGATTGCAATCGCCTTCTCCTCTTCAGTTGTATTGCT GACTTGTTGTCTCGGTCTATATGTTTTCTTTTGTTTGTATCGTACTTCGCGTAAAACCTTCCTATATTGTATGATAGTGT GTTTTAGTGGCGCTATGTACACCACGTATGTTCAAGGACAAAATAAGCCTCTGGGAGAGTCCTACGAAGCTACAAGAGGA GTGATTTATAATACACCTCTTATTAACGGGGATCGCCTATCATTTCAAGTTGAAGATCAGAATAAAAATATAGTGCAGTT AAGTTACAAAATGAAATCAGCCTCGGAAAAGAAACAAATGCGACAATTACATGCAGGAGTGTCATGTATATTTGATGGTG AGAGGAAAGAACCACAAATAGCTCGGAATTTTCATGGGTTTAATTATCGTGATTATTTATATAAGCAAAATATTCATTTC ATATTGGAAGCTACATATATTTCTGAATGCCGTAAAACATCGTTGTCACTTGTGCAATGGATTCTTCTTTTGAGGCAGCA AGCAATCTTAGGAGTTACAGAAATGTTTCCAGAGCAATCAGGCGCTTTTATGAACGCGTTACTATTTGGTGATAGACAAC AAATGACATTTGAAGTTGAAGGGCAATATCAACAATTCGGTCTTGTGCATTTGTTGGCGATTTCAGGATCGCATATCGTA TTGTTAATGGTGATTGTGTATTTTATTTTGCTAAGAAGTGGTGTGACAAGGGAGATAGCAACAGTATGTCTTATCTTCTT CATTCCTATATATATGATTTTAGCAGGAGCGTCACCGTCTGTTATAAGAGCTTCTATAACAGGAGTTTTAATGTTAATTG CTTTTATGTGTTCTATTCGTTTATCTAGCTTAGATGCTTTAAGTATAACAGCTATATGTATGCTTATATTTGATCCATAT CTCGTGTTTAATATTGGCTTTCAGTTTTCTTTTGTTGGGAGTTTTGCTTTACTTTTATCTGCCCCGCTCTTACTAGAGAG TGGTAATGGAGTAATTAGAAATTCTATTTATATTTCTCTTATTTCACAGCTCGTTAGTACTCCGATTTTGTTATATCACT TCGGTTATTATTCTCCATATAGTATTTTTCTAAATATCCTTTACGTTCCGTTTTTATCTCTCATTGTATTGCCGTGTAGT ATTATTATTTTGATATGTTTGCCGATCATCCCGTTTCTTGCAAAAAGCTTTGCGAATGTACTATCAATAGGTTTGAATCT TTCTAATGATTTTTTAAGTTATTGTGAAAGTTTACCATTTACCCGTCTTAATTTCGGGCAAACACCTATACTTCTTGTAG CCTTATATTGCGTGAGTATTATTAGTGTATTGATGGTTTGGGAAAGGCGAATATCTAAGGGAATGGTGTTTATATTTGCG GGCATATTTCTTTTTATTAGTACAGGTCATTATGTATATCCGTATTTTCGAGAAAGTGGGAGTGTTACATTTCTTGATGT TGGCCAGGGGGATGCAATATTAATTCGCCTCCCGTATGATCAAGAGATTTACCTTATTGACACTGGTGGAACAATTCGTT TAAACAAGGAAGAATGGCAACGGAAAAAACATGAATTTTCTGTTGGAAATGATGTTTTGATCCCTTATTTACAAAAGGAA GGTATTAAAAAAATTGATAAATTAATTGTAACGCATGGAGATGCAGATCATATCGGTGCTGCACAAGAATTATTATCAAA TATAACCGTAAAAGAAGTTGTATTTGGTCGAAAGGAACAAGAGGCAATATTAGAAAAAGCAGTAAAGAAACAGGCGTTAG AAAAGGAAGTGAAAATAAGTGAAGTGGGGGAAGGAGAGAGTTGGCGCGTAAATGAAGCGGAATTTTTTGTGCTAGCACCA ACAGGGAAAGAAAGAAGTGAAAATAACGCTTCAATTGTACTGTGGGCAAAATTAGGAGGGATAACGTGGCTGTTTACAGG TGATTTAGAAGAAGGAGAGAAGGGTTTAGTAGCTACATATCCAGATTTACGGGCGGATGTTTTAAAGGTTGCTCATCATG GAAGTAATACGTCATCTATAACGCCTTTTTTGAGCGCCGTACAGCCTAATATAGCGATTATTTCTGTCGGTGAACGGAAT AGGTATGGGCACCCTCATAAGGAAGGTATAGAGCGTTTTGAGAAGATGGCGATTGAAATATGGCGCACGGATAAGCAAGG TGCTATTTCCTATGTTTTTAAAGAGGAACGCGGAACGTTTCGTAGCAAAATCACATATGATGAAACACGGAATAGATAA
Upstream 100 bases:
>100_bases AAGAACTATTTGCATCTTTAGAAAAAGAGAACTTATCAATGGAAGAATTACAGCATGTATTCACGAAAGCAAAAATGATG CTATAAGGAGTGAGTATGAG
Downstream 100 bases:
>100_bases AAAAGACTGCTAGTAAGCAGCAGTCTTTAAGAACCGATAAATTTAATAACAGTTGCAATGATGAAAAGTGTTGCGAAAAA ACCAAATGAGACGATAAATC
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 772; Mature: 772
Protein sequence:
>772_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLGLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDVLIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGERN RYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR
Sequences:
>Translated_772_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLGLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDVLIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGERN RYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR >Mature_772_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLGLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDVLIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGERN RYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 87084; Mature: 87084
Theoretical pI: Translated: 7.80; Mature: 7.80
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLGLYVFFCLYRTSRKTFLYCMIVCFSGAMY CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE TTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQM EEEEECCCCCCCCCHHHCCCEEEECCEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHH RQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQW HHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH ILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVHLLAISGSHIV HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEEECCCHHH LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIR HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISL HHCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCEEECCCCEEHHHHHHHH ISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANV HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA HHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQ HHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECHHHHH RKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQ HHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHCCCHH EAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGG HHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEEECC ITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGERN EEEEEECCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCC RYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR CCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHCEECHHCCCC >Mature Secondary Structure MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLGLYVFFCLYRTSRKTFLYCMIVCFSGAMY CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE TTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQM EEEEECCCCCCCCCHHHCCCEEEECCEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHH RQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQW HHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH ILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVHLLAISGSHIV HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEEECCCHHH LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIR HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISL HHCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCEEECCCCEEHHHHHHHH ISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANV HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA HHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQ HHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECHHHHH RKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQ HHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHCCCHH EAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGG HHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEEECC ITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGERN EEEEEECCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCC RYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR CCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHCEECHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]