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The map label for this gene is holA [H]

Identifier: 49187218

GI number: 49187218

Start: 4137443

End: 4138453

Strand: Reverse

Name: holA [H]

Synonym: BAS4222

Alternate gene names: 49187218

Gene position: 4138453-4137443 (Counterclockwise)

Preceding gene: 49187219

Following gene: 49187216

Centisome position: 79.15

GC content: 35.31

Gene sequence:

>1011_bases
ATGAGTGATATACATAAAAAGATTAAAAAAAAGCAGTTTGCTCCGTTGTATTTACTGTATGGAACGGAAGCGTTTTTTAT
AAATGAAACGATAAAGCTTATTACAACAGAAGCGCTTGAAGAGGAAGATCGCGAGTTTAATGTTGTGACATATGATTTAG
AAGAAGCGTATTTAGAAGATGTGGTTGAGGATGCACGTACACTTCCTTTTTTCGGAGAACGTAAAGTGTTATTAATAAAA
TCACCATTATTTTTAACGTCACAAAAAGAAAAGTTAGAACAAAATATAAAAATTTTAGAAGAATATATCGGGGAACCTTC
TCCATTTTCTATTCTTGTTTTTGTTGCGCCTTACGAAAAGCTTGATGAACGAAAAAAAATTACAAAACTATTAAAGAAAA
CAGCAGATATAGTAGAAGCGAATGCGATGCAAGTGCAGGATGTTCAAAAGTGGATTGTAGCTCGTGCAGAGGAAGGGCAT
GTACATATTGATAATGCAGCTGTTAGTTTATTGTTAGAGCTTGTGGGAAGTAATGTGACGATGTTGGCGAAGGAAATGGA
CAAGTTAACGTTATACGTCGGTATGGGCGGAGAGATTACGCCGAAACTTGTTGCAGAGCTTGTGCCAAAATCAGTTGAAC
AAAATGTATTTGCTTTAACAGAAAAAGTGGTAAAAAAAGATATCGCAGGTGCGATGCAAATTTTGGATGGATTATTTACG
CAGCAGGAGGAACCGATTAAATTGCTTGCGTTGTTAGTAAGTCAATTCCGCTTGCTGCATCAAGTAAAAGAGTTACAGCA
GCGTGGTTATGGACAAAATCAAATTGCTTCTCATATTGGTGTACATCCATATCGTGTAAAGTTAGCGATGAATCAAACGA
AGTTTTTCTCTTTTGAAGAACTAAAAAAAGTGATTATAGAATTGGCGGAAGCTGATTATAGTATGAAGACTGGAAAAATG
GATAAGAAACTTGTGCTTGAGTTTTTCTTAATGCGATTAAATCATATGTGA

Upstream 100 bases:

>100_bases
AAAGGGACGGGTTATACAGCCTGTTCCTTTGTACTTGTAAAACAAAAGCTAGGGCATTAGTATAAAATATATATTGCCAA
GTTAGGGAGTAGGAAAAAGT

Downstream 100 bases:

>100_bases
TGATACAAAAAGTTCACGTGCTTAGCACGTGAACTTTTTTGGATATAAAAAAACGATCCAAATGGATCGTTTTTTAAACG
CCTTACGCGTTTACTTGTTT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSDIHKKIKKKQFAPLYLLYGTEAFFINETIKLITTEALEEEDREFNVVTYDLEEAYLEDVVEDARTLPFFGERKVLLIK
SPLFLTSQKEKLEQNIKILEEYIGEPSPFSILVFVAPYEKLDERKKITKLLKKTADIVEANAMQVQDVQKWIVARAEEGH
VHIDNAAVSLLLELVGSNVTMLAKEMDKLTLYVGMGGEITPKLVAELVPKSVEQNVFALTEKVVKKDIAGAMQILDGLFT
QQEEPIKLLALLVSQFRLLHQVKELQQRGYGQNQIASHIGVHPYRVKLAMNQTKFFSFEELKKVIIELAEADYSMKTGKM
DKKLVLEFFLMRLNHM

Sequences:

>Translated_336_residues
MSDIHKKIKKKQFAPLYLLYGTEAFFINETIKLITTEALEEEDREFNVVTYDLEEAYLEDVVEDARTLPFFGERKVLLIK
SPLFLTSQKEKLEQNIKILEEYIGEPSPFSILVFVAPYEKLDERKKITKLLKKTADIVEANAMQVQDVQKWIVARAEEGH
VHIDNAAVSLLLELVGSNVTMLAKEMDKLTLYVGMGGEITPKLVAELVPKSVEQNVFALTEKVVKKDIAGAMQILDGLFT
QQEEPIKLLALLVSQFRLLHQVKELQQRGYGQNQIASHIGVHPYRVKLAMNQTKFFSFEELKKVIIELAEADYSMKTGKM
DKKLVLEFFLMRLNHM
>Mature_335_residues
SDIHKKIKKKQFAPLYLLYGTEAFFINETIKLITTEALEEEDREFNVVTYDLEEAYLEDVVEDARTLPFFGERKVLLIKS
PLFLTSQKEKLEQNIKILEEYIGEPSPFSILVFVAPYEKLDERKKITKLLKKTADIVEANAMQVQDVQKWIVARAEEGHV
HIDNAAVSLLLELVGSNVTMLAKEMDKLTLYVGMGGEITPKLVAELVPKSVEQNVFALTEKVVKKDIAGAMQILDGLFTQ
QEEPIKLLALLVSQFRLLHQVKELQQRGYGQNQIASHIGVHPYRVKLAMNQTKFFSFEELKKVIIELAEADYSMKTGKMD
KKLVLEFFLMRLNHM

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 38524; Mature: 38392

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIHKKIKKKQFAPLYLLYGTEAFFINETIKLITTEALEEEDREFNVVTYDLEEAYLED
CCHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHH
VVEDARTLPFFGERKVLLIKSPLFLTSQKEKLEQNIKILEEYIGEPSPFSILVFVAPYEK
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
LDERKKITKLLKKTADIVEANAMQVQDVQKWIVARAEEGHVHIDNAAVSLLLELVGSNVT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCHH
MLAKEMDKLTLYVGMGGEITPKLVAELVPKSVEQNVFALTEKVVKKDIAGAMQILDGLFT
HHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QQEEPIKLLALLVSQFRLLHQVKELQQRGYGQNQIASHIGVHPYRVKLAMNQTKFFSFEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCHHCCCHHH
LKKVIIELAEADYSMKTGKMDKKLVLEFFLMRLNHM
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDIHKKIKKKQFAPLYLLYGTEAFFINETIKLITTEALEEEDREFNVVTYDLEEAYLED
CHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHH
VVEDARTLPFFGERKVLLIKSPLFLTSQKEKLEQNIKILEEYIGEPSPFSILVFVAPYEK
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
LDERKKITKLLKKTADIVEANAMQVQDVQKWIVARAEEGHVHIDNAAVSLLLELVGSNVT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCHH
MLAKEMDKLTLYVGMGGEITPKLVAELVPKSVEQNVFALTEKVVKKDIAGAMQILDGLFT
HHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QQEEPIKLLALLVSQFRLLHQVKELQQRGYGQNQIASHIGVHPYRVKLAMNQTKFFSFEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCHHCCCHHH
LKKVIIELAEADYSMKTGKMDKKLVLEFFLMRLNHM
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]