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The map label for this gene is ahpC [H]

Identifier: 49183358

GI number: 49183358

Start: 355910

End: 356473

Strand: Reverse

Name: ahpC [H]

Synonym: BAS0330

Alternate gene names: 49183358

Gene position: 356473-355910 (Counterclockwise)

Preceding gene: 49183362

Following gene: 49183357

Centisome position: 6.82

GC content: 40.25

Gene sequence:

>564_bases
ATGTTATTAATCGGCACAGAAGTAAAACCGTTTAAAGCTAATGCTTACCATAATGGAGAATTTATCCAAGTTACTGACGA
AAGTTTAAAAGGAAAATGGAGTGTAGTTTGTTTCTACCCAGCTGACTTCACATTCGTTTGCCCAACTGAACTTGAAGACT
TACAAAACCAATATGCAACTCTTAAAGAGTTAGGCGTTGAAGTATACTCTGTATCTACAGACACTCACTTCACTCACAAA
GCATGGCATGATAGCTCAGAAACTATCGGTAAAATCGAGTACATCATGATTGGTGACCCAACTCGCACAATCACTACAAA
CTTCAACGTTTTAATGGAAGAAGAAGGTCTTGCTGCTCGTGGTACATTCATCATCGATCCAGACGGTGTTATCCAATCTA
TGGAAATCAATGCTGACGGTATCGGCCGTGACGCAAGCATTCTTGTTAACAAAATTAAAGCAGCTCAATACGTACGTAAC
AACCCAGGTGAAGTTTGCCCAGCTAAATGGCAAGAGGGTTCTGCTACACTTAAACCAAGCCTTGACCTTGTAGGCAAAAT
CTAA

Upstream 100 bases:

>100_bases
ATTAATATCGAATTAGAATTATTATAGTTAATTAAAAAATATATTTTATGAGCACACTATTTTTTGATGCTCAAAACCAA
CATTTAGGAGGAATTTTAAT

Downstream 100 bases:

>100_bases
GGAGTTCGATCAAAATGATACTAGATGCAGATATAAAAACACAACTATCCCAATACCTTCAGTTAATGGAGAACGATATT
TTACTTAAAGTAAGCGCAGG

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MLLIGTEVKPFKANAYHNGEFIQVTDESLKGKWSVVCFYPADFTFVCPTELEDLQNQYATLKELGVEVYSVSTDTHFTHK
AWHDSSETIGKIEYIMIGDPTRTITTNFNVLMEEEGLAARGTFIIDPDGVIQSMEINADGIGRDASILVNKIKAAQYVRN
NPGEVCPAKWQEGSATLKPSLDLVGKI

Sequences:

>Translated_187_residues
MLLIGTEVKPFKANAYHNGEFIQVTDESLKGKWSVVCFYPADFTFVCPTELEDLQNQYATLKELGVEVYSVSTDTHFTHK
AWHDSSETIGKIEYIMIGDPTRTITTNFNVLMEEEGLAARGTFIIDPDGVIQSMEINADGIGRDASILVNKIKAAQYVRN
NPGEVCPAKWQEGSATLKPSLDLVGKI
>Mature_187_residues
MLLIGTEVKPFKANAYHNGEFIQVTDESLKGKWSVVCFYPADFTFVCPTELEDLQNQYATLKELGVEVYSVSTDTHFTHK
AWHDSSETIGKIEYIMIGDPTRTITTNFNVLMEEEGLAARGTFIIDPDGVIQSMEINADGIGRDASILVNKIKAAQYVRN
NPGEVCPAKWQEGSATLKPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=184, Percent_Identity=41.304347826087, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=42.1965317919075, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=40.6593406593407, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=37.3626373626374, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=37.3626373626374, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=37.3626373626374, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=35, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=46.9135802469136, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=66.8449197860963, Blast_Score=277, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=38.9830508474576, Blast_Score=139, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=182, Percent_Identity=37.9120879120879, Blast_Score=133, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI193204376, Length=182, Percent_Identity=37.9120879120879, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=36.5714285714286, Blast_Score=121, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=32.5966850828729, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.9830508474576, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357347, Length=189, Percent_Identity=34.9206349206349, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24656348, Length=173, Percent_Identity=36.9942196531792, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17864676, Length=173, Percent_Identity=36.9942196531792, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=35.2941176470588, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=35.2941176470588, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=25.9493670886076, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20721; Mature: 20721

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIGTEVKPFKANAYHNGEFIQVTDESLKGKWSVVCFYPADFTFVCPTELEDLQNQYAT
CEEECCCCCCEECCCEECCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LKELGVEVYSVSTDTHFTHKAWHDSSETIGKIEYIMIGDPTRTITTNFNVLMEEEGLAAR
HHHCCEEEEEEECCCCEEECCCCCCCCCCCEEEEEEECCCCEEEEECEEEEEECCCCEEC
GTFIIDPDGVIQSMEINADGIGRDASILVNKIKAAQYVRNNPGEVCPAKWQEGSATLKPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC
>Mature Secondary Structure
MLLIGTEVKPFKANAYHNGEFIQVTDESLKGKWSVVCFYPADFTFVCPTELEDLQNQYAT
CEEECCCCCCEECCCEECCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LKELGVEVYSVSTDTHFTHKAWHDSSETIGKIEYIMIGDPTRTITTNFNVLMEEEGLAAR
HHHCCEEEEEEECCCCEEECCCCCCCCCCCEEEEEEECCCCEEEEECEEEEEECCCCEEC
GTFIIDPDGVIQSMEINADGIGRDASILVNKIKAAQYVRNNPGEVCPAKWQEGSATLKPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]